Minnesota Twins vs New York Mets Prediction 4/21/2026 Today's MLB Picks

MATCHUP	Minnesota Twins	New York Mets
Team Records	11-11	7-15
Where	Citi Field, Queens, New York
When	Tuesday, April 21, 2026
Time	07:10 PM EDT
TV	MLB.TV

The Minnesota Twins and New York Mets meet Tuesday in MLB action at Citi Field. Here’s a Minnesota Twins vs. New York Mets Prediction. This article will include a Minnesota Twins vs. New York Mets Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 11-11 on the year and play the Rays and Mariners next. The Minnesota Twins are batting .230 on the season and have a .332 OBP, and a .381 slugging percentage. The Minnesota Twins pitching staff has a 4.06 ERA and a 1.37 WHIP. Josh Bell leads the Minnesota Twins with 20 hits and 15 RBI, while Luke Keaschall and Byron Buxton have combined for 37 hits and 14 RBI.

Simeon Woods Richardson gets the ball for the Minnesota Twins, and he is 0-3 with a 6.10 ERA and 11 strikeouts this season. This will be Woods Richardson’s second career game against the New York Mets.

New York Mets Betting Preview

The New York Mets are 7-15 on the year and play the Rockies and Nationals next. The New York Mets are batting. 226 on the season, have a .288 OBP, and have a .336 slugging percentage. The New York Mets pitching staff has a 4.06 ERA and a 1.28 WHIP. Bo Bichette leads the New York Mets with 20 hits and 9 RBI, while Francisco Lindor and Luis Robert Jr. have combined for 36 hits and 8 RBI.

Nolan McLean gets the ball for the New York Mets, and he is 1-1 with a 2.28 ERA and 28 strikeouts this season. This will be McLean’s first career game against the Minnesota Twins.

Why the New York Mets will win

The Twins have lost each of their last seven road games following an extra innings loss.
The Mets have won seven of their last eight night games at Citi Field after going to extra innings.
The Twins have failed to cover the run line each of their last seven games against NL East opponents that held a losing record.
The favorites have covered the run line in each of the Twins’ last four games at Citi Field.
The Mets have led after 5 innings in three of their last four games against the Twins at Citi Field.

Why the Minnesota Twins will win

The Mets have lost each of their last 10 games following a loss.
The underdogs have won each of the Mets’ last five games at Citi Field.
The Mets have failed to cover the run line in each of their last seven games at Citi Field.
The underdogs have covered the run line in seven of the Twins’ last eight games.
The Mets have trailed after 3 innings in four of their last five games at Citi Field.
The Twins have led after 5 innings in eight of their last 10 games against opponents that held a losing record.

Total Runs Facts

Eight of the Twins’ last nine games against NL East opponents have gone UNDER the total runs line.
Five of the Mets’ last six night games against AL Central opponents have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in eight of the Twins’ last nine games.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the last six night games between the Twins and Mets at Citi Field.

New York Mets Player Prop Facts

Bo Bichette has recorded at least one hit in each of his last 14 home appearances against AL Central opponents.
Juan Soto has hit a home run in three of the Mets’ last four games as favorites against AL Central opponents.

Minnesota Twins Player Prop Facts

Byron Buxton has recorded at least one hit in 10 of his last 11 appearances in night games against teams that held a losing record.
Ryan Jeffers has hit a home run in each of his last two appearances in night games against teams that held a losing record.

Matchup/League Facts

The Mets rank 30th in the league for on-base percentage this season (.288).
The Mets rank 29th in the league for slugging percentage this season (.336).
The Twins rank 25th in the league for hits this season (166).
The Twins rank T6th in the league for home runs this season (26).