Minnesota Twins vs Chicago White Sox Prediction 9/5/2026 Today’s MLB Picks

The Minnesota Twins and the Chicago White Sox will meet on Saturday night in the second game of a three‑game American League Central series at Guaranteed Rate Field in Chicago, Illinois.

Minnesota Twins Betting Preview

The Minnesota Twins enter Saturday’s contest with a 67–74 overall record (3rd in the American League Central) and a 29–40 mark on the road. The Twins offense has been competitive at times this season. Minnesota has compiled 659 runs scored (7th in MLB), 232 doubles, 166 home runs, and a .246 team batting average which ranks 15th in Major League Baseball.

The Twins arrive at tonight’s game in below average form. Minnesota has lost two consecutive games, including an 11–6 loss to the Detroit Tigers two days ago.

The Minnesota Twins will turn to right hander Taj Bradley in this game. In 27 starts made this season, Bradley has compiled a 10–6 win loss record, a 3.85 ERA, a 1.26 WHIP and 178 strikeouts which ranks ninth in Major League Baseball. Taj Bradley performed at a high level in his most recent outing, allowing one earned run while scattering four hits and three walks in the Minnesota Twins dominant 11-1 victory over the Detroit Tigers last month. Bradley will look to continue his strong pitching performances in this evening’s matchup with the Chicago White Sox.

The Twins lineup features outfielder Byron Buxton and designated hitter Josh Bell. Byron Buxton arrives at this contest with a .254 batting average, 25 home runs, 46 RBIs, 30 walks, 7 stolen bases and an .829 OPS. Josh Bell has tallied a .253 batting average, 18 home runs, 84 RBIs (11th in MLB) and a .746 OPS.                                                           

Chicago White Sox Betting Preview

The Chicago White Sox enter Saturday night’s matchup with a 73–67 overall record (1st in the American League Central) and a 42–27 mark at home. Chicago has played subpar baseball recently, losing four of the team’s last six games, including a 2-0 shutout loss to the Houston Astros three days ago.

The White Sox will start left hander Anthony Kay in today’s game. In 26 starts made in 2026, Kay has compiled a 9–7 win loss record, a 4.28 ERA, a 1.35 WHIP and 113 strikeouts in 137.0 innings pitched. Kay arrives at this contest in below average form, allowing four earned runs or more in two of his last three starts made this season.

The Chicago White Sox lineup features Miguel Vargas, who has tallied 30 home runs, 77 RBIs, 30 doubles, and an .851 OPS, and Tristan Peters, who has amassed 12 home runs, 52 RBIs, 24 doubles, and an .813 OPS.             

Why the Minnesota Twins will win.

• Offensive balance. Byron Buxton and Josh Bell have been key contributors for the Minnesota Twins lineup.

• Starting pitching. In 2026, Taj Bradley has compiled a 10–6 win‑loss record, a 3.85 ERA, a 1.26 WHIP and 178 strikeouts.

Why the Chicago White Sox will win.

• Home field edge. The Chicago White Sox have played competitive baseball at Guaranteed Rate Field this season.

• Offensive balance. Miguel Vargas and Tristan Peters provide a strong core to the White Sox lineup.

• Motivation factor. The White Sox have lost four of the team’s last six games.

Minnesota Twins vs. Chicago White Sox Prediction

In my opinion, this matchup favors the Minnesota Twins. Why? Minnesota hurler Taj Bradley has performed at a high level this season, compiling a 10–6 win loss record, a 3.85 ERA, a 1.26 WHIP and 178 strikeouts which ranks ninth in Major League Baseball. Conversely, Chicago starting pitcher Anthony Kay arrives at this contest in below average form, allowing four earned runs or more in two of his last three starts made this season. With that said, the Twins are the clear side to be on in this one. I am backing the Minnesota Twins on the moneyline in this game.

Hans Geevers's Pick: Minnesota Twins ML