Miami Marlins vs St. Louis Cardinals Prediction 07/30/2025 Picks

In this article, we will formulate a Marlins vs Cardinals prediction for this MLB game on Wednesday, July 30, at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Betting Preview

The Miami Marlins (51-55, 27-26 Away) beat the Kansas City Royals, San Diego Padres, and Milwaukee Brewers to open the second half of the season brightly. Following last night’s 5-0 victory over the Cardinals in Game 2 of the current series, the Marlins have a chance to add another series win in the rubber match today. Graham Pauley led the offense with two RBI, while Sandy Alcantara got the win after allowing no runs on three hits with four strikeouts and three walks across 5.0 innings of work.

This season, the Marlins average 4.25 runs per game (20th in the MLB) on a .252/.315/.393 triple-slash. When it comes to pitching, the Marlins’ staff has a 4.44 ERA (24th) and 1.31 WHIP (21st). Kyle Stowers leads the Marlins with a .302 batting average, 23 home runs, and 63 RBI this season.

Cal Quantrill will take the mound for the Marlins on Wednesday. The 30-year-old right-hander has a 3-8 record in 20 starts this year with a 5.05 ERA and 1.33 WHIP in 92.2 innings.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals (55-54, 32-23 Home) were swept by the Arizona Diamondbacks, lost to the Colorado Rockies, and split a series with the San Diego Padres. St. Louis played well in Game 1 against the Marlins, when it secured a 7-1 win, but then failed to get on the scoreboard in a 5-0 defeat on Tuesday. The Cards were outhit 12-4, while Sonny Gray took the loss after allowing three runs on eight hits with five strikeouts and one walk in 5.0 innings.

This year, the Cardinals average 4.47 runs per game (13th in the MLB) on a .251/.321/.393 triple-slash. When it comes to pitching, the Cardinals’ staff has a 4.19 ERA (21st) and 1.29 WHIP (18th). Willson Contreras leads the Cardinals with a .259 batting average, 14 home runs, and 61 RBI this season.

The projected starting pitcher for the Cardinals is Miles Mikolas, who is 6-7 in 20 starts this season, with a 4.94 ERA and 1.30 WHIP in 102.0 innings.

Why the Marlins will cover

• The underdogs have won four of the Cardinals’ last five games at Busch Stadium.
• The Cardinals have lost three of their last four games as favorites.
• The Marlins have covered the run line in 13 of their last 14 road games following a win.
• The Cardinals have failed to cover the run line in eight of their last nine Wednesday games as favorites against NL East opponents.
• The Marlins have led after 5 innings in three of their last four games against National League opponents that held a winning record.

Matchup/League Facts

• The Cardinals rank 29th in the league for strikeouts this season (793).
• The Cardinals rank 3rd in the league for walks allowed this season (288).
• The Marlins rank 25th in the league for walks this season (315).
• The Marlins rank T7th in the league for triples this season (18).

Marlins vs Cardinals Prediction

The Cardinals won six of the previous ten H2H encounters, but the Marlins were better in three of the last four. I expect a tight affair that could go either way, but I am backing the Marlins to put up a fight, stay close, and cover a +1.5 run line. Cal Quantrill is having a solid month, posting a 3.66 ERA. He allowed more than two runs only once in his previous six starts and should keep the Cardinals in bay here. Miles Mikolas, on the other hand, is playing in a hot-and-cold form; he surrendered 5+ runs in three of his last five starts, and he usually allows a lot of runs following a shutout game. Mikolas had a shutout in his latest start, so I expect him to struggle this time around. Back the Marlins to cover the run line.