Aug 20, 2025; Denver, Colorado, USA; Los Angeles Dodgers two-way player Shohei Ohtani (17) at the plate the third inning against the Colorado Rockies at Coors Field. Mandatory Credit: Ron Chenoy-Imagn Images

Los Angeles Dodgers vs San Diego Padres Prediction 8/24/2025 Today’s MLB Picks

Pick details

Los Angeles (73-57) vs San Diego (74-56)

August 24, 2025 at 04:10 PM EDT

The Line: Betting Odds: San Diego -115 — Over/Under: +7.5

(Get latest betting odds)

The San Diego Padres and the Los Angeles Dodgers meet Sunday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego Padres vs. Los Angeles Dodgers prediction.

Starting Pitching Matchup

The San Diego Padres send out Nick Pivetta for the start here and Pivetta is 13-4 with a 2.81 ERA and 154 strikeouts this season. In his last five starts against the Dodgers, Pivetta is 1-0 with a 2.59 ERA and 32 strikeouts. Yoshinobu Yamamoto will get the start for the Dodgers in this one and is 10-8 with a 2.90 ERA and 151 strikeouts this season. In his career, Yamamoto is 0-2 with an 8.03 ERA and 13 strikeouts against the Padres.

San Diego Padres Recap

The San Diego Padres come into this one looking to add on to their win over the Dodgers from Saturday’s matchup by a final score of 5-1 to climb to 74-56 this season. After this series, the Padres will take to the road for an interleague series against the Seattle Mariners.

Padres Pick Up 5th Straight Victory

Manny Machado has 145 hits including a team-high 32 doubles, 21 home runs, 77 RBIs and 12 stolen bases while Fernando Tatis Jr. has 128 hits with 17 home runs and 52 RBIs along with 25 stolen bases of his own this season. Luis Arraez has added 144 hits with 27 doubles, 4 triples, 6 home runs and 47 RBIs while Jackson Merrill’s added 91 hits with 9 home runs and 51 RBIs as well. Xander Bogaerts also has 28 doubles and 19 stolen bases as well this season. Gavin Sheets also has 18 doubles, 17 home runs and 58 RBIs as well this season.

Why the San Diego Padres will win

  • The Padres have won eight of their last nine home games after playing the previous day.
  • The Dodgers have lost each of their last three road games against teams that held a winning record.
  • The Padres have covered the run line each of their last 11 day games against teams that held a winning record.
  • The Dodgers have failed to cover the run line in nine of their last 10 day games against teams that held a winning record.

San Diego Padres Player Prop Facts

  • Nick Pivetta has recorded six or more strikeouts in each of his last four appearances in day games against teams that held a winning record.
  • Fernando Tatis Jr. has recorded at least one hit in each of the Padres’ last 11 day games against opponents that held a winning record.
  • Nick Pivetta has recorded a win in six of his last seven appearances with the Padres as home favorites against NL opponents.
  • Luis Arraez has recorded at least one Double in three of the Padres’ last four games against opponents that held a winning record.
  • Luis Campusano has hit at least one home run in two of his last three appearances with the Padres as favorites against the Dodgers.
  • Nick Pivetta ranks T2nd in the league for Wins (13) this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to bounce back after a tough showing against the Padres to fall to 73-57 this season. After this set, the Dodgers will take on the Cincinnati Reds in a series at home.

Dodgers Looking To Avoid Sweep

Shohei Ohtani has 138 hits including 17 doubles, 44 home runs, 83 RBIs and 8 triples while Tommy Edman has 69 hits with 12 home runs and 44 RBIs. Michael Conforto has 63 hits with 18 doubles while Teoscar Hernandez has 101 hits with 21 home runs, 24 doubles and 76 RBIs as well this season. Ohtani has a team-high 17 stolen bases while Max Muncy has 10 doubles but also has 73 strikeouts so far this season. Mookie Betts has also chipped in 13 home runs and 57 RBIs as well on the year. Freddie Freeman has also logged 131 hits with a team-high 32 doubles, 16 home runs and 72 RBIs. Andy Pages also has 127 hits with 21 doubles, 21 home runs and 71 RBIs as well this season.

Why the Los Angeles Dodgers will win

  • The Dodgers have won each of their last 11 day games against NL West opponents following a loss.
  • The Padres have lost 10 of their last 11 day games against the Dodgers at Petco Park following a home win.
  • The Dodgers have covered the run line in eight of their last nine day games against NL West opponents following a road loss.
  • The Padres have failed to cover the run line in six of their last seven day games against the Dodgers at Petco Park following a home win.

Los Angeles Dodgers Player Prop Facts

  • Mookie Betts has hit a home run in four of his last five appearances with the Dodgers as road underdogs against the Padres.
  • Miguel Rojas has recorded at least one hit in each of his last 12 road appearances against NL West opponents.
  • Teoscar Hernandez has recorded a Double in each of the Dodgers’ last five games as underdogs against NL opponents.
  • Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.621) this season.

Total Runs Facts

  • Eight of the Dodgers’ last nine games as underdogs against NL West opponents have gone OVER the total runs line.
  • Eight of the Padres’ last nine games as favorites against the Dodgers have gone OVER the total runs line.

Los Angeles Dodgers vs. San Diego Padres Prediction

I’m siding with the under in this game. I think this is going to feel like a playoff type atmosphere, with the Dodgers trying to avoid the sweep at the hands of a rival and the Padres trying to get it done with two decent starting options on the mound and two quality bullpens as well. I think this could easily be a pitchers duel into the 7th and 8th innings so give me the under here.

Chris Ruffolo's Pick: Under 7.5

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