Los Angeles Dodgers vs San Diego Padres Prediction 6/27/2026 Today’s MLB Picks

The Los Angeles Dodgers and the San Diego Padres meet Saturday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. San Diego Padres prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Yoshinobu Yamamoto for the start here and Yamamoto is 7-5 with a 2.65 ERA and 86 strikeouts this season. Randy Vasquez will get the start for San Diego and is 6-5 with a 4.17 ERA and 59 strikeouts this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to shake off a 7-1 loss at the hands of the Padres last time out to sit at 52-30 this season. After this series, the Dodgers will head on the road for a game against the Athletics.

Dodgers Have Three-Game Win Streak Snapped

Andy Pages has 84 hits with 18 doubles, 15 home runs and 58 RBIs while Teoscar Hernandez has 50 hits with 8 doubles, 7 home runs and 31 RBIs. Shohei Ohtani has 82 hits with 15 doubles, 17 home runs and 46 RBIs and Freddie Freeman has 85 hits with 20 doubles, a triple, 13 home runs and 43 RBIs this season. Will Smith has 6 home runs and 23 RBIs as well this season. Max Muncy’s added 65 hits with 11 doubles, 16 home runs and 34 RBIs and Kyle Tucker has 64 hits with 16 doubles, 6 home runs and 40 RBIs this season.

San Diego Padres Recap

The San Diego Padres come into this game looking to build on their win over the Dodgers from Saturday to improve to 43-37 this season. After this series, the Padres will head on the road for a series against the Chicago Cubs.

Padres Win 4 Straight

Jackson Merrill has 62 hits with 15 doubles, 8 home runs and 31 RBIs while Ramon Laureano has 37 hits with 6 doubles, 2 triples, 7 home runs and 21 RBIs as well on the year. Fernando Tatis Jr. has 87 hits with 15 doubles and 29 RBIs and Xander Bogaerts has 60 hits with 4 doubles, 8 home runs and 30 RBIs. Manny Machado also has 53 hits with 14 doubles, 14 home runs and 43 RBIs as well on the year.

Los Angeles Dodgers @ San Diego Padres Betting Trends: June 27, 2026

• Probable Starting Pitcher: Randy Vasquez      Record this season: 6-5      ERA: 4.17
• Home Record: 3-3
• Last 5 against Dodgers: 0-2

Why the San Diego Padres will win

• The Padres have won each of their last eight Saturday games as underdogs.
• The Dodgers have lost three of their last four games as favorites against National League opponents.
• The Padres have covered the run line in each of their last seven home games against NL West opponents following a win.
• The Dodgers have failed to cover the run line in 10 of their last 11 games.
• The Padres have led after 3 innings in four of their last five games against the Dodgers.
• The Padres have led after 5 innings in seven of their last eight home games against NL West opponents that held a winning record.

• Probable Starting Pitcher: Yoshinobu Yamamoto      Record this season: 7-5      ERA: 2.65
• Road Record: 4-2
• Last 5 against Padres: 2-2

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last nine road games following a loss.
• The Dodgers have covered the run line in four of their last five games against National League opponents following a loss.
• The Padres have failed to cover the run line in four of their last five home games after playing the previous day.
• The Dodgers have led after 3 innings in four of their last five road games against opponents that held a winning record.
• The Dodgers have led after 5 innings in 11 of their last 12 games as favorites against National League opponents.

Total Runs Facts

• Each of the Dodgers’ last four games against National League opponents have gone OVER the total runs line.
• Four of the Padres’ last five games as underdogs against National League opponents have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of the Padres’ last 12 night games against National League opponents.
• There has been no run scored during the first inning in eight of the Dodgers’ last nine games as favorites against National League opponents.

San Diego Padres Player Prop Facts

• Ty France has hit a home run in each of the Padres’ last two games.
• Randy Vasquez has recorded a win in four of his last five home appearances against opponents that held a winning record.
• Randy Vasquez has recorded four or more strikeouts in three of his last four home appearances against opponents that held a winning record.
• Miguel Andujar has recorded at least one hit in each of his last 11 Saturday appearances against NL teams that held a winning record.
• Fernando Tatis Jr. ranks T6th in the league in Steals (19) this season.

Los Angeles Dodgers Player Prop Facts

• Mookie Betts has hit a home run in each of the Dodgers’ last two games.
• Yoshinobu Yamamoto has recorded seven or more strikeouts in seven of his last eight appearances against NL West opponents.
• Yoshinobu Yamamoto has recorded a win in seven of his last eight appearances against opponents that held a winning record.
• Tommy Edman has recorded at least one hit in each of his last eight appearances against the Padres after playing the previous day.
• Shohei Ohtani ranks 4th amongst qualified players for On Base Percentage (.412) this season.

Matchup/League Facts

• The Padres rank 30th in the league for runs scored this season (316).
• The Padres rank 30th in the league for hits this season (574).
• The Dodgers rank 1st in the league for batting average this season (.261).
• The Dodgers rank 1st in the league for slugging percentage this season (.437).

Los Angeles Dodgers vs. San Diego Padres Prediction

I’m on the Dodgers here. San Diego broke out the bats against Roki Sasaki on Friday but I think they’re in much tougher here against who I feel is the ace of this Dodger rotation in Yamamoto. The Padres will have plenty of spots to provide value against the Dodgers, but Randy Vasquez is headed for regression and this could be a spot where that regression rears it’s ugly head. Give me the Dodgers.

Chris Ruffolo's Pick: LA Dodgers -195