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Kansas City Royals vs Minnesota Twins Prediction 5/23/25 MLB Picks

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Minnesota Twins (27-22) vs Kansas City Royals (28-23)

May 23, 2025 at 08:10 PM EDT

The Line: Betting Odds: Minnesota Twins -162 / Kansas City Royals +136 — Over/Under: 7.5

(Get latest betting odds)

The Kansas City Royals and Minnesota Twins meet Friday in MLB action at Target Field. Here’s a Kansas City Royals vs Minnesota Twins Prediction. This article will include a Kansas City Royals vs Minnesota Twins Pick.

Kansas City Royals Betting Preview

The Kansas City Royals are 28-23 on the year and play the Reds, Tigers, and Cardinals next. The Kansas City Royals are batting .245 on the season, have a .300 OBP, and a .366 slugging percentage. The Kansas City Royals pitching staff has a 3.03 ERA and a 1.18 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 60 hits and 28 RBI, while Maikel Garcia and Vinnie Pasquantino have combined for 101 hits and 51 RBI. 

Noah Cameron gets the ball for the Kansas City Royals, and he is 1-1 with a 0.71 ERA and 6 strikeouts this season. This will be Cameron’s first career game against the Minnesota Twins.

Minnesota Twins Betting Preview

The Minnesota Twins are 27-22 on the year and play the Rays, Mariners, and Athletics next. The Minnesota Twins are batting .242 on the season, have a .312 OBP, and a .384 slugging percentage. The Minnesota Twins pitching staff has a 3.28 ERA and a 1.15 WHIP. Trevor Larnach leads the Minnesota Twins with 44 hits and 23 RBI, while Ty France and Byron Buxton have combined for 84 hits and 51 RBI.

Pablo Lopez gets the ball for the Minnesota Twins, and he is 4-2 with a 2.40 ERA and 49 strikeouts this season. Lopez is 5-1 with a 2.23 ERA and 51 strikeouts in his career against the Kansas City Royals.

Why the Minnesota Twins will win

  • The Twins have won each of their last 10 games against the Royals at Target Field following a loss.
  • The Royals have lost 22 of their last 23 road games against the Twins following a win.
  • The Royals have failed to cover the run line in each of their last six night games at Target Field following a win.
  • The Twins have covered the run line in 10 of their last 11 night games against the Royals at Target Field following a home loss.
  • The Royals have trailed after 5 innings in each of their last four night games against AL Central opponents that held a winning record.

Why the Kansas City Royals will win

  • The Royals have won seven of their last eight games against the Twins.
  • The Twins have lost four of their last five night games against American League opponents that held a winning record.
  • The Royals have covered the run line in each of their last nine games as underdogs.
  • The Twins have failed to cover the run line in eight of their last nine games at Target Field against American League opponents that held a winning record.

Minnesota Twins Player Prop Facts

  • Ryan Jeffers has hit a home run in three of his last five appearances in night games against AL teams that held a winning record.
  • Ty France has recorded at least one RBI in six of his last seven appearances at Target Field against AL opponents that held a winning record.
  • Trevor Larnach has scored at least one run in 10 of his last 11 appearances after not playing the previous day.
  • Pablo Lopez has recorded a win in five of his last six appearances against the Royals.
  • Pablo Lopez has recorded six or more strikeouts in each of his last six appearances in night games.
  • Ty France has recorded at least one Single in eight of his last nine appearances against AL Central opponents that held a winning record.
  • Trevor Larnach has recorded at least one hit in each of his last nine appearances with the Twins as home favorites against the Royals.

Kansas City Royals Player Prop Facts

  • Bobby Witt Jr. has hit a home run in two of the Royals’ last three games against the Twins at Target Field.
  • Bobby Witt Jr. has recorded a Double in each of the Royals’ last three games against the Twins.
  • Cavan Biggio has scored a run in five of his last six appearances with the Royals as underdogs against AL opponents.
  • Bobby Witt Jr. has recorded at least one RBI in four of the Royals’ last five road games against the Twins.
  • Michael Massey has recorded at least one Single in eight of the Royals’ last nine night games against AL Central opponents that held a winning record.
  • Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 17 road games against AL Central opponents that held a winning record.
  • Bobby Witt Jr. ranks T7th in the league in Hits (60) this season.

Kansas City Royals vs Minnesota Twins Prediction

The Royals and the plus money always have value given their consistency with their pitching staff and their above-average offense. The Royals are a good team. However, Cameron has just 12.2 innings in his big league career, so the jury is still out. I need a larger sample size to trust. The Twins have lost two games in the last 20 days, and Lopez looks like his all-star self. Lopez has a 2.40 ERA and 0.93 WHIP on the season, and the Twins have won five of his last seven games. The price isn’t too steep. I’ll lay the juice with the Twins on Friday night. 

Randy Chambers's Pick: Minnesota Twins -162

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