Houston Astros vs Toronto Blue Jays Prediction 6/22/2026 Today’s MLB Picks

The Houston Astros and the Toronto Blue Jays meet Monday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

The Houston Astros will send out Hunter Brown here and Brown is 1-0 with a 1.10 ERA and 24 strikeouts this season. The Toronto Blue Jays did not have a starting pitcher announced at the time that this article was posted.

Houston Astros Recap

The Houston Astros come into this game looking to add on to their 2-1 win over the Cleveland Guardians last time out to sit at 37-42 this season. After this series, the Astros will head on the road for a series against the Detroit Tigers.

Astros Win 4 Of Last 5

Yordan Alvarez has 91 hits with 15 doubles, 25 home runs and 56 RBIs while Christian Walker has 70 hits with 14 doubles, 18 home runs and 52 RBIs on the year. Jose Altuve’s chipped in 50 hits with 11 doubles, 8 home runs and 20 RBIs and Isaac Paredes has 63 hits with 14 doubles, 10 home runs and 37 RBIs. Cam Smith also has 57 hits with 12 doubles, 7 home runs and 26 RBIs.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to add on to their win over the Cubs by a final score of 8-6 on Saturday to improve to 38-39 this season before Sunday’s postponement. After this series, the Blue Jays will take on the Texas Rangers in a series at home.

Blue Jays Win 4 Of Last 5

Andres Gimenez has 56 hits with 11 doubles, a triple, 7 home runs and 33 RBIs while Ernie Clement has 85 hits with 20 doubles, 7 home runs and 28 RBIs. Kazuma Okamoto has 62 hits with 10 doubles, 16 home runs, 45 RBIs and a team-high 99 strikeouts while George Springer also has 11 doubles and 8 homers with 21 RBIs. Vladimir Guerrero Jr. has 74 hits with 12 doubles, 4 home runs and 31 RBIs as well. Jesus Sanchez also has 58 hits with 14 doubles, 7 home runs and 29 RBIs.

Houston Astros @ Toronto Blue Jays Betting Trends: June 22, 2026

• Probable Starting Pitcher: Shane Bieber      Record this season: –      ERA: –
• Home Record: –
• Last 5 against Astros: 1-1

Why the Toronto Blue Jays will win

• The Blue Jays have won each of their last eight night games against AL West opponents.
• The Astros have lost each of their last six road games against American League opponents following a home win.
• The Blue Jays have covered the run line in nine of their last 10 night games against American League opponents.
• The Astros have failed to cover the run line in each of their last five road games following a home win.
• The Blue Jays have led after 5 innings in seven of their last eight games as favorites against American League opponents.
• The Astros have trailed after 3 innings in eight of their last nine night games.

• Probable Starting Pitcher: Hunter Brown      Record this season: 1-0      ERA: 1.10
• Road Record: 0-0
• Last 5 against Blue Jays: 2-1

Why the Houston Astros will win

• The Blue Jays have lost eight of their last nine games as home favorites against American League opponents following a road win.
• The Astros have won each of their last eight Monday games against AL East opponents.
• The Blue Jays have failed to cover the run line in each of their last eight Monday home games.
• The Astros have covered the run line in 10 of their last 11 games against the Blue Jays.
• The Astros have led after 3 innings in each of their last four night games against the Blue Jays.
• The Blue Jays have trailed after 5 innings in each of their last eight Monday home games.

Total Runs Facts

• Each of the last seven games between the Astros and Blue Jays have gone UNDER the total runs line.
• Each of the Astros’ last four games as underdogs against the Blue Jays have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in seven of the Astros’ last eight games as road underdogs.
• There has been at least one run scored in the first inning in five of the last six games between the Astros and Blue Jays at Rogers Centre.

Toronto Blue Jays Player Prop Facts

• Alejandro Kirk has hit at least one home run in each of his last three home appearances against AL opponents that held a losing record.
• George Springer has recorded at least one hit in 12 of his last 13 home appearances against AL West opponents that held a losing record.
• Shane Bieber has recorded five or more strikeouts in 16 of his 17 previous appearances with his team as a favorite against AL West opponents.
• Shane Bieber has recorded a win in seven of his last eight home appearances against opponents that held a losing record.

Houston Astros Player Prop Facts

• Yordan Alvarez has hit a home run in three of the Astros’ last four games at Rogers Centre against opponents that held a losing record.
• Yainer Diaz has recorded at least one hit in each of his last nine appearances in night games.
• Yordan Alvarez ranks 1st amongst qualified players for Slugging Percentage (.640) this season.

Matchup/League Facts

• The Blue Jays rank 30th in the league for triples this season (4).
• The Blue Jays rank 2nd in the league for strikeouts against this season (562).
• The Astros rank 30th in the league for steals this season (24).
• The Astros rank 29th in the league for triples this season (5).

Houston Astros vs. Toronto Blue Jays Prediction

I’m on the Blue Jays here. I know Hunter Brown has looked solid in his limited action so far this season, but the Blue Jays have started to pick up their play once again and I think Toronto can get to Brown here. It’ll be interesting to see who Toronto throws out, as this was supposed to be the return of Shane Bieber but with Sunday’s postponement we could see Dylan Cease. Either way I think Toronto gets the better of the opener and gets the win here.

Chris Ruffolo's Pick: Toronto -110