Guardians vs Red Sox Prediction 9/1/2025 Today’s MLB Picks

In this article we will formulate a Guardians vs Red Sox prediction for this MLB game on Monday, September 1st at Fenway Park in Boston, Massachusetts. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 68-67 this year after they won two out of three against Seattle by scores of 5-4, 4-3, and 2-4. In their game three loss, Cleveland led 2-0 in the third inning, but failed to score over the last six innings for the loss. The Guardians recorded just two hits in the game and they were led by Schneemann, who went 1-3 with one home run and two RBIs in the loss. Cleveland started Bibee, who allowed six hits and four earned runs over 6.1 innings for the loss, while Festa and Allard closed out the game. 

Prior to that series, the Guardians won two out of three against the Rays, but did lose all three against the Rangers before that. Cleveland has won four of their last five games and they are currently third in the AL Central standings. The Cleveland pitching staff has a 3.92 ERA with a 1.31 WHIP and a .243 opponent batting average, while the offense has scored 519 runs with a .223 batting average and a .294 on base percentage this season. Jose Ramirez has led Cleveland with 26 home runs and 68 RBIs, while Kyle Manzardo has added 23 home runs and 60 RBIs this year. The projected starting pitcher for Cleveland is Parker Messick, who is 1-0 with a 0.66 ERA and a 0.88 WHIP over 13.2 innings pitched this year. 

Boston Red Sox Betting Preview

The Boston Red Sox are 76-62 this season after they lost two out of three against Pittsburgh by scores of 2-4, 3-10, and 5-2. In their game three win, Boston trailed 1-0 in the fourth inning, but they scored the next five runs to pull away in the victory. The Red Sox recorded eight hits in the game and they were led by Duran, who went 2-2 with one home run and three RBIs in the win. Boston started Giolito, who allowed three hits and one earned run over 6.0 innings for the win, while Slaten allowed one earned run in relief. 

Prior to that series, the Red Sox swept the Orioles in four games and won three out of four against the Yankees. Boston has won five of their last seven games and they are currently third in the AL East standings. The Boston pitching staff has a 3.68 ERA with a 1.29 WHIP and a .243 opponent batting average, while their offense has scored 678 runs with a .252 batting average and a .323 on base percentage this season. Wilyer Abreu (IL) has led Boston with 22 home runs and 69 RBIs, while Trevor Story has added 22 home runs and 84 RBIs this year. The projected starting pitcher for Boston is Brayan Bello, who is 10-6 with a 2.99 ERA and a 1.21 WHIP over 141.2 innings pitched this year. 

Why the Red Sox will beat the Guardians 

The Red Sox have won each of their last seven day games against American League opponents following a win.
The Guardians have lost each of their last five road games.
The Red Sox have covered the run line each of their last five home games against teams that held a winning record.
The Guardians have failed to cover the run line each of their last four day games against American League opponents that held a winning record.
The Guardians have trailed after 3 innings in each of their last three day games against AL East opponents.
The Guardians have trailed after 5 innings in six of their last seven road games against AL East opponents that held a winning record.

Why the Guardians will beat the Red Sox

The Red Sox have lost five of their last six games as home favorites after playing the previous day.
The Guardians have won each of their last six road games against teams that held a winning record.
The Guardians have covered the run line in 11 of their last 12 road games against teams that held a winning record.
The Red Sox have failed to cover the run line in five of their last six games as home favorites against the Guardians following a home win.
The Red Sox have trailed after 5 innings in each of their last three games as home favorites against American League opponents.

Total Runs Facts

Each of the Red Sox’s last five games against AL Central opponents have gone OVER the total runs line.
Each of the Guardians’ last three road games against AL East opponents have gone UNDER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Guardians’ last seven games as underdogs.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Red Sox’s last six games at Fenway Park.

Boston Red Sox Player Prop Facts

Trevor Story has recorded at least one hit in each of the Red Sox’s last 11 home games against AL opponents.
Connor Wong has hit a home run in each of his last three appearances with the Red Sox as home favorites against the Guardians.

Cleveland Guardians Player Prop Facts

Austin Hedges has hit a home run in two of his three previous appearances at Fenway Park against AL East opponents that held a winning record.
Steven Kwan has recorded a Double in each of the Guardians’ last three day games against AL opponents that held a winning record.
Steven Kwan has recorded at least one hit in 15 of his last 16 appearances in day games against AL teams that held a winning record.

Matchup/League Facts

The Red Sox rank 27th in the league for strikeouts against this season (1218).
The Red Sox are one of only four teams in the league to rank top 10 in both steals and batting average this season.
The Guardians rank 30th in the league for on-base percentage this season (.294).
The Guardians rank 29th in the league for RBIs this season (500).

David Racey is 16-7 (70%) overall in the last two days. Click here for his premium plays for this today!

Guardians vs Red Sox Prediction 

Cleveland had their four game winning streak snapped on Sunday afternoon, but each game is very important for them, as they are trying to stay in the wild card race. The Guardians are 33-34 on the road this year, while the Red Sox are 42-27 at home. Boston is now trailing the Blue Jays and the Yankees in the East, and they are starting Bello, who has allowed two earned runs or fewer in four of his last five outings. The Guardians are going with Messick, who has allowed one earned run and 11 hits in 13.2 innings this year. I think we are going to see a lower scoring battle here, so I like the under in this game.