Jun 19, 2025; Los Angeles, California, USA;  Los Angeles Dodgers pitcher Yoshinobu Yamamoto (18) delivers a pitch during the first inning against the San Diego Padres at Dodger Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

Dodgers vs Orioles Prediction 9/6/2025 Today’s MLB Picks

Pick details

Baltimore Orioles (65-76) vs Los Angeles Dodgers (78-63)

September 6, 2025 at 07:05 PM EDT

The Line: Betting Odds: Dodgers -150 — Over/Under: +8.5

(Get latest betting odds)

In this article we will formulate a Dodgers vs Orioles prediction for this MLB game on Saturday, September 6th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 78-63 this year after they lost game one by a score of 2-1 on Friday night. Los Angeles tied the game at one in the sixth inning, but they couldn’t find anymore offense in the low scoring loss. The Dodgers recorded five hits in the game and they were led by Freeman, who went 2-4 with one home run and one RBI in the loss. Los Angeles started Ohtani, who allowed three hits and zero earned runs over 3.2 innings, while Scott picked up the loss in relief. 

Prior to this series, the Dodgers lost all three against the Pirates and two out of three against the Diamondbacks. Los Angeles has lost six of their last seven games and they are currently first in the NL West standings. The Los Angeles pitching staff has a 4.11 ERA with a 1.29 WHIP and a .241 opponent batting average, while their offense has scored 711 runs with a .251 batting average and a .328 on base percentage this season. Shohei Ohtani has led LA with 46 home runs and 87 RBIs, while Andy Pages has added 24 home runs and 79 RBIs this year. The projected starting pitcher for Los Angeles is Yoshinobu Yamamoto, who is 11-8 with a 2.82 ERA and a 1.05 WHIP over 146.2 innings pitched this year. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 65-76 this season after they won game one by a score of 2-1 last night. Baltimore blew an early 1-0 lead, but they scored in the bottom of the ninth to walk-off with the victory. The Orioles recorded five hits and they committed one error in the game, while they were led by Basallo, who went 1-4 with one home run and one RBI in the win. Baltimore started Kremer, who allowed zero hits and zero earned runs over 3.0 innings, while Cano picked up the win. 

Prior to this series, the Orioles swept the Padres in three games, but lost two out of three against the Giants before that. Baltimore has won four games in a row and they are currently last in the AL East standings. The Baltimore pitching staff has a 4.67 ERA with a 1.38 WHIP and a .261 opponent batting average, while their offense has scored 614 runs with a .241 batting average and a .308 on base percentage this season. Jackson Holliday has led Baltimore with 16 home runs and 52 RBIs, while Gunnar Henderson has added 16 home runs and 61 RBIs this year. The projected starting pitcher for Baltimore is Trevor Rogers, who is 8-2 with a 1.39 ERA and a 0.82 WHIP over 90.1 innings pitched this season. 

Why the Orioles will beat the Dodgers 

The Dodgers have lost each of their last four games as favorites.
The underdogs have won each of the Orioles’ last four games.
The Dodgers have failed to cover the run line in each of their last seven games as favorites.
The Orioles have covered the run line each of their last six games against teams that held a winning record.
The Orioles have led after 5 innings in five of their last six games as home underdogs against National League opponents.
The Orioles have led after 3 innings in three of their last four home games against NL West opponents.

Why the Dodgers will beat the Orioles 

The Orioles have lost six of their last seven home games after playing the previous day.
The Dodgers have won 10 of their last 12 games against AL East opponents following a loss.
The Orioles have failed to cover the run line in nine of their last 10 home games against NL West opponents following a home win.
The Dodgers have covered the run line in nine of their last 11 games against AL East opponents following a loss.

Total Runs Facts

Nine of the Orioles’ last 10 games as home underdogs have gone UNDER the total runs line.
Five of the Dodgers’ last six night games against AL East opponents have gone UNDER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Dodgers’ last five games as favorites against American League opponents.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the last five night games between the Dodgers and Orioles.

Dodgers vs Orioles Prediction 

Los Angeles comes into this matchup favored to win yet again, but they continue to play very poorly and have lost six of their last seven. The Dodgers are just 33-37 on the road this year, while the Orioles are 32-37 at home. Baltimore has won four in a row and they are starting Rogers, who has been one of the top pitchers in the AL over the last few weeks. LA is going with Yamamoto, who has allowed two earned runs or fewer in two straight outings. Take the under in this contest.

David Racey's Pick: Under 8.5

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