Colorado Rockies vs San Diego Padres Prediction 9/12/2025 Today’s MLB Picks

The Colorado Rockies and San Diego Padres meet Friday in MLB action at Petco Park. Here’s a Colorado Rockies vs San Diego Padres Prediction. This article will include a Colorado Rockies vs San Diego Padres Pick.

Colorado Rockies Betting Preview

The Colorado Rockies are 40-107 on the year and play the Marlins, Angels, and Mariners next. The Colorado Rockies are batting .238 on the season, have a .295 OBP, and a .388 slugging percentage. The Colorado Rockies pitching staff has a 5.98 ERA and a 1.60 WHIP. Hunter Goodman leads the Colorado Rockies with 135 hits and 87 RBI, while Jordan Beck and Brenton Doyle have combined for 241 hits and 105 RBI.

Tanner Gordon gets the ball for the Colorado Rockies, and he is 5-6 with a 6.60 ERA and 46 strikeouts this season. Gordon is 0-1 with a 6.52 ERA and 9 strikeouts in his career against the San Diego Padres.

San Diego Padres Betting Preview

The San Diego Padres are 80-67 on the year and play the Mets, White Sox, and Brewers next. The San Diego Padres are batting .251 on the season, have a .320 OBP, and a .385 slugging percentage. The San Diego Padres pitching staff has a 3.62 ERA and a 1.20 WHIP. Luis Arraez leads the San Diego Padres with 162 hits and 55 RBI while Manny Machado and Fernando Tatis Jr. have combined for 298 hits and 147 RBI.

JP Sears gets the ball for the San Diego Padres, and he is 8-10 with a 5.01 ERA and 105 strikeouts this season. Sears is 2-0 with a 3.18 ERA and 7 strikeouts in his career against the Colorado Rockies.

Colorado Rockies @ San Diego Padres Betting Trends: September 12, 2025

• Probable Starting Pitcher: JP Sears      Record this season: 8-10      ERA: 5.01
• Home Record: 4-5
• Last 5 against Rockies: 2-0

Why the San Diego Padres will win

• The Rockies have lost each of their last nine games after playing the previous day.
• The Padres have won each of their last eight Friday home games against National League opponents.
• The Rockies have failed to cover the run line in each of their last nine games as underdogs after playing the previous day.
• The favorites have covered the run line in nine of the Rockies’ last 10 games.
• The Padres have led after 5 innings in nine of their last 10 games against NL West opponents.
• The Padres have led after 3 innings in four of their last five games against the Rockies at Petco Park.

• Probable Starting Pitcher: Tanner Gordon      Record this season: 5-6      ERA: 6.60
• Road Record: 1-3
• Last 5 against Padres: 0-1

Why the Colorado Rockies will win

• The Padres have lost five of their last seven games as home favorites after playing the previous day.
• The Padres have failed to cover the run line in seven of their last eight games at Petco Park.
• The road team has covered the run line in five of the Padres’ last six games.

Total Runs Facts

• Each of the Padres’ last five games have gone UNDER the total runs line.
• Seven of the Rockies’ last nine games as road underdogs have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rockies’ last seven night games against NL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last nine Friday night games.

San Diego Padres Player Prop Facts

• Jackson Merrill has hit a home run in each of the Padres’ last two games as favorites against the Rockies.
• JP Sears has recorded six or more strikeouts in three of his last four home appearances against NL opponents.
• JP Sears has recorded a win in three of his last four appearances in night games against NL West teams that held a losing record.
• Xander Bogaerts has recorded a Double in three of his last four appearances in night games against NL West teams that held a losing record.
• Jose Iglesias has recorded two or more hits in four of his last five appearances with his team as a home favorite against the Rockies.
• Jake Cronenworth ranks 10th amongst qualified players for On Base Percentage (.370) this season.

Colorado Rockies Player Prop Facts

• Brenton Doyle has hit a home run in six of the Rockies’ last 22 games as underdogs against NL West opponents.
• Thairo Estrada has recorded at least one hit in each of his last nine appearances against the Padres at Petco Park.

Matchup/League Facts

• The Padres rank 29th in the league for home runs this season (129).
• The Padres rank 2nd in the league for ERA this season (3.62).
• The Rockies rank 30th in the league for walks this season (366).
• The Rockies rank 30th in the league for ERA this season (5.98).

Colorado Rockies vs San Diego Padres Prediction

Another Rockies game, another chance to fade one of the worst teams in baseball history. I keep saying that, and the Rockies keep losing. In fact, the Rockies haven’t scored in their last two games. The Rockies have scored a combined four runs in their last five games. The Padres have been shaky over the last couple of weeks and Sears isn’t having a great season, but it’s the Rockies. You’ve stacked up a mountain of profit just blindly fading the Rockies this season. Don’t stop now. Give me the Padres and the RL for max betting value.