Sep 25, 2026; Chicago, Illinois, USA;  Chicago White Sox first baseman Munetaka Murakami (5) high fives manager Will Venable (1), right, after he hit a home run during the seventh inning against the Colorado Rockies at Rate Field.  Mandatory Credit: Matt Marton-Imagn Images
IMAGN IMAGES via Reuters Connect

Colorado Rockies vs Chicago White Sox Prediction 9/27/2026 Today’s MLB Picks

Pick details

MATCHUP Colorado Rockies Chicago White Sox
Team Records 58-103 83-78
Spread +1.5 -119 -1.5 -102
Moneyline +170 -208
Total Over 8.5 (-105) Under 8.5 (-115)
Where Rate Field, Chicago, Illinois
When Sunday, September 27, 2026
Time 03:10 PM EDT
TV MLB.TV

The Colorado Rockies and Chicago White Sox meet Sunday in MLB action at Rate Field. Here’s a Colorado Rockies vs. Chicago White Sox Prediction. This article will include a Colorado Rockies vs. Chicago White Sox Pick.

Colorado Rockies Betting Preview 


The Colorado Rockies are 58-103 on the year. The Colorado Rockies are batting .254 on the season and have a .323 OBP and a .417 slugging percentage. The Colorado Rockies’ pitching staff has a 5.59 ERA and a 1.53 WHIP. TJ Rumfield leads the Colorado Rockies with 161 hits and 71 RBI, while Jake McCarthy and Hunter Goodman have combined for 282 hits and 167 RBI.

Kyle Freeland gets the ball for the Colorado Rockies, and he is 4-11 with a 6.58 ERA and 106 strikeouts this season. Freeland is 3-0 with a 2.03 ERA and 23 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview 


The Chicago White Sox are 83-78 on the season. The Chicago White Sox are batting .236 on the season, have a .321 OBP, and have a .404 slugging percentage. The Chicago White Sox pitching staff has a 4.13 ERA and a 1.32 WHIP. Chase Meidroth leads the Chicago White Sox with 155 hits and 63 RBI, while Sam Antonacci and Miguel Vargas have combined for 274 hits and 140 RBI.

Anthony Kay gets the ball for the Chicago White Sox, and he is 9-9 with a 4.53 ERA and 125 strikeouts this season. This will be Kay’s first career game against the Colorado Rockies.

Why the Chicago White Sox will win

  • The Rockies have lost each of their last seven day games against AL opponents following a road win.
  • The White Sox have won each of their last six Sunday home games.
  • The Rockies have failed to cover the run line in seven of their last eight games as road underdogs.
  • The White Sox have covered the run line in seven of their last eight day games against NL West opponents following a home loss.
  • The White Sox have led after 3 innings in five of their last six home games.
  • The White Sox have led after 5 innings in each of their last four day games against opponents that held a losing record.

Why the Colorado Rockies will win

  • The White Sox have lost five of their last seven games as favorites against NL opponents.
  • The road team has won five of the Rockies’ last six games.
  • The White Sox have failed to cover the run line in nine of their last 10 games against NL opponents.
  • The underdogs have covered the run line in five of the last six games between the Rockies and White Sox.
  • The Rockies have led after 3 innings in three of their last four games against the White Sox at Rate Field.
  • The Rockies have led after 5 innings in three of their last four games at Rate Field.

Total Runs Facts

  • Five of the White Sox’s last six games have gone OVER the total runs line.
  • Four of the Rockies’ last five games as underdogs against AL opponents have gone UNDER the total runs line.
  • There has been at least one run scored in the first inning in 12 of the Rockies’ last 13 games as underdogs.
  • There has been at least one run scored in the first inning in eight of the White Sox’s last nine games.

Chicago White Sox Player Prop Facts

  • Brenton Doyle has hit a home run in two of his last three appearances with the White Sox as favorites.
  • Anthony Kay has recorded four or more strikeouts in five of his last six appearances at Rate Field.
  • Brenton Doyle has recorded at least one hit in each of his last seven appearances after playing the previous day.

Colorado Rockies Player Prop Facts

  • Hunter Goodman has hit at least one home run in two of his last three road appearances.
  • Kyle Freeland has recorded five or more strikeouts in each of his last three appearances against AL opponents that held a winning record.
  • TJ Rumfield has recorded at least one hit in each of his seven previous appearances with the Rockies as road underdogs against AL Central opponents.
  • Hunter Goodman ranks 4th amongst qualified players for Slugging Percentage (.532) this season.

Matchup/League Facts

  • The White Sox rank 5th in the league for home runs this season (209).
  • The White Sox rank 5th in the league for RBIs this season (736).
  • The Rockies rank 30th in the league for opponent batting average this season (.289).
  • The Rockies rank 30th in the league for hits allowed this season (1627).

Colorado Rockies vs Chicago White Sox Prediction


The White Sox don’t have anything to play for, but they should still win at home. The Rockies suck, and Freeland is rocking a 6.58 ERA and 1.52 WHIP through 131.1 innings. I’ve been on the White Sox all season, and they’re the third most profitable team in baseball. Only the Rays and Brewers have earned more money this season than the White Sox. I’ll back the White Sox again and lay the RL to shave down the price.

Randy Chambers's Pick: Chicago White Sox -1.5

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