Colorado Rockies vs Arizona Diamondbacks Prediction 5/24/2026 Today’s MLB Picks

The Colorado Rockies and the Arizona Diamondbacks meet Sunday in MLB action from Chase Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Colorado Rockies vs. Arizona Diamondbacks prediction.

Starting Pitching Matchup

The Colorado Rockies will send out Jose Quintana for the start here and Quintana is 2-2 with a 4.08 ERA and 20 strikeouts this season. In his last five starts against Arizona, Quintana is 1-1 with a 5.24 ERA and 12 strikeouts. Arizona will start Ryne Nelson here and Nelson is 1-3 with a 5.19 ERA and 46 strikeouts this season. In his career, Nelson is 1-1 with an 8.80 ERA and 7 strikeouts against Colorado.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their 5-4 loss at the hands of the Diamondbacks on Saturday to fall to 20-33 this season. After this series, the Rockies will head on the road for a series against the Los Angeles Dodgers.

Rockies Drop 4 Of Last 5

TJ Rumfield has 50 hits with 8 doubles, a triple, 6 home runs and 25 RBIs while Ezequiel Tovar has 34 hits with 11 doubles, a home run and 13 RBIs. Hunter Goodman’s added 41 hits with 8 doubles, 11 home runs and 19 RBIs and Jordan Beck has 10 RBIs as well on the year. Troy Johnston has 48 hits with 13 doubles, 2 home runs and 22 RBIs. Willi Castro also has 33 hits with 8 doubles, 2 home runs and 16 RBIs.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to bounce back from add on to their win over Colorado from Saturday to improve to 27-24 this season. After this series, the Diamondbacks will head on the road for a series against the San Francisco Giants.

Diamondbacks Win 7 Of Last 9

Corbin Carroll has 46 hits including 11 doubles, 6 triples, 7 home runs and 26 RBIs while Alek Thomas has logged 9 doubles with 2 home runs and 10 RBIs as well this season. Ketel Marte has 44 hits with 7 doubles, 7 home runs and 22 RBIs and Geraldo Perdomo has 35 hits, with 8 doubles, 3 triples, 2 home runs and 15 RBIs as well this season. Nolan Arenado also has 42 hits with 9 doubles, 7 home runs and 25 RBIs and Jose Fernandez has 36 hits with 3 home runs and 14 RBIs this season. Ildemaro Vargas also has 55 hits with 8 doubles, 2 triples, 7 home runs and 32 RBIs.

Colorado Rockies @ Arizona Diamondbacks Betting Trends: May 24, 2026

• Probable Starting Pitcher: Ryne Nelson      Record this season: 1-3      ERA: 5.19
• Home Record: 0-2
• Last 5 against Rockies: 1-1

Why the Arizona Diamondbacks will win

• The Rockies have lost each of their last 15 day games against NL West opponents following a road loss.
• The Diamondbacks have won seven of their last eight home games.
• The Rockies have failed to cover the run line in nine of their last 10 day games against NL West opponents following a road loss.
• The Diamondbacks have covered the run line in each of their last five day games against National League opponents following a home win.
• The Diamondbacks have led after 3 innings in each of their last six day games against the Rockies at Chase Field.
• The Diamondbacks have led after 5 innings in each of their last six day games against the Rockies at Chase Field.
• The Rockies have lost the first inning in each of their last seven Sunday road games against NL West opponents.

• Probable Starting Pitcher: Jose Quintana      Record this season: 2-2      ERA: 4.08
• Road Record: 1-1
• Last 5 against Diamondbacks: 1-1

Why the Colorado Rockies will win

• The Diamondbacks have lost three of their last four games as favorites against the Rockies following a win.
• The Rockies have won four of their last six games as road underdogs following a road loss.
• The underdogs have covered the run line in each of the Rockies’ last six games.
• The Diamondbacks have failed to cover the run line in each of their last four games against the Rockies following a win.
• The Rockies have won the first inning in three of their last four day games against opponents that held a winning record.

Total Runs Facts

• Four of the Rockies’ last five day games against NL West opponents have gone OVER the total runs line.
• Fifteen of the Diamondbacks’ last 19 day games as favorites have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rockies’ last five day games at Chase Field.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last four games between the Rockies and Diamondbacks.

Arizona Diamondbacks Player Prop Facts

• Ryne Nelson has recorded a win in three of his last four appearances in day games against NL teams that held a losing record.
• Lourdes Gurriel Jr. has hit a home run in three of his last nine appearances against the Rockies.
• Corbin Carroll has recorded at least one hit in each of his last 16 appearances against NL West opponents that held a losing record.
• Ildemaro Vargas ranks T7th amongst qualified players for Batting Average (.312) this season.

Colorado Rockies Player Prop Facts

• Jose Quintana has recorded three or more strikeouts in 15 of his 18 previous appearances in day games against NL West teams that held a winning record.
• TJ Rumfield has recorded at least one hit in each of his last 10 road appearances after playing the previous day.
• Brenton Doyle has hit a home run in each of his last two road appearances against the Diamondbacks.
• Jose Quintana has recorded a win in three of his last four road appearances against NL West opponents.
• Troy Johnston ranks 4th amongst qualified players for Batting Average (.323) this season.

Matchup/League Facts

• The Diamondbacks rank 1st in the league for triples this season (14).
• The Diamondbacks rank 30th in the league for strikeouts this season (368).
• The Rockies rank 30th in the league for opponent batting average this season (.275).
• The Rockies rank 30th in the league for hits allowed this season (501).

Colorado Rockies vs. Arizona Diamondbacks Prediction

I’m on the over in this game. I just think that while Quintana is one of the better starting options the Rockies have, he’s still a lefty going against an Arizona team that’s raking against southpaws right now. On the other side, Ryne Nelson’s really struggled at home this season and I think that he gets tagged here as well so I’m rolling with the over in this one.

Chris Ruffolo's Pick: Over 9