Sep 2, 2025; Minneapolis, Minnesota, USA; Chicago White Sox left fielder Andrew Benintendi (23) slides into third base safely after a fly ball against the Minnesota Twins in the sixth inning at Target Field. Mandatory Credit: Jesse Johnson-Imagn Images

Chicago White Sox vs Minnesota Twins Prediction 9/3/2025 Today’s MLB Picks

Pick details

Chicago (51-88) vs Minnesota (62-76)

September 3, 2025 at 07:40 PM EDT

The Line: Betting Odds: Minnesota -1.5 — Over/Under: +8.5

(Get latest betting odds)

The Chicago White Sox and Minnesota Twins meet Wednesday in MLB action at Target Field. Here’s a Chicago White Sox vs Minnesota Twins Prediction. This article will include a Chicago White Sox vs Minnesota Twins Pick.

Chicago White Sox Betting Preview


The Chicago White Sox are 51-88 on the year and play the Tigers, Rays, and Guardians next. The Chicago White Sox are batting .234 on the season, have a .304 OBP, and a .376 slugging percentage. The Chicago White Sox pitching staff has a 4.22 ERA and a 1.37 WHIP. Lenyn Sosa leads the Chicago White Sox with 118 hits and 62 RBI, while Miguel Vargas and Andrew Benintendi have combined for 198 hits and 106 RBI.

Yoendrys Gomez gets the ball for the Chicago White Sox, and he is 3-2 with a 5.20 ERA and 35 strikeouts this season. This will be Gomez’s second career game against the Minnesota Twins.

Minnesota Twins Betting Preview


The Minnesota Twins are 62-76 on the year and play the Royals, Angels, and Diamondbacks next. The Minnesota Twins are batting .238 on the season, have a .311 OBP, and a .397 slugging percentage. The Minnesota Twins pitching staff has a 4.51 ERA and a 1.32 WHIP. Trevor Larnach leads the Minnesota Twins with 111 hits and 55 RBI while Byron Buxton and Brooks Lee have combined for 211 hits and 129 RBI.

Zebby Matthews gets the ball for the Minnesota Twins, and he is 4-4 with a 5.06 ERA and 70 strikeouts this season. This will be Matthews’ second career game against the Chicago White Sox.

Chicago White Sox vs Minnesota Twins Prediction


As I’ve said many times this year and a couple of times in this series. I’ve made nice coin blindly fading the White Sox over the years. However, I’m not laying juice with the Twins just because they’re playing the White Sox. The Twins suck too. In fact, maybe more than the White Sox based off the first two games of this series. I don’t want to back the White Sox, but I’m not laying juice with the Twins. I’ll pinch my nose and grab the White Sox at a more favorable price if forced to pick.

Randy Chambers's Pick: Chicago White Sox

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