Chicago Cubs vs Milwaukee Brewers Prediction 6/26/2026 Today’s MLB Picks

The Chicago Cubs and Milwaukee Brewers meet Friday in MLB action at American Family Field. Here’s a Chicago Cubs vs Milwaukee Brewers Prediction. This article will include a Chicago Cubs vs Milwaukee Brewers Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 44-37 on the year and play the Padres and Cardinals next. The Chicago Cubs are batting .243 on the season and have a .337 OBP and a .403 slugging percentage. The Chicago Cubs’ pitching staff has a 4.27 ERA and a 1.24 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 88 hits and 45 RBI, while Alex Bregman and Nico Hoerner have combined for 152 hits and 61 RBI.

Colin Rea gets the ball for the Chicago Cubs, and he is 5-5 with a 4.99 ERA and 59 strikeouts this season. Rea is 1-1 with a 6.23 ERA and 5 strikeouts in his career against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 49-29 on the year and play the Diamondbacks and Reds next. The Milwaukee Brewers are batting. 254 on the season, have a .338 OBP, and have a .391 slugging percentage. The Milwaukee Brewers’ pitching staff has a 3.38 ERA and a 1.18 WHIP. William Contreras leads the Milwaukee Brewers with 87 hits and 48 RBI, while Brice Turang and Jake Bauers have combined for 139 hits and 95 RBI.

Jacob Misiorowski gets the ball for the Milwaukee Brewers, and he is 8-3 with a 1.45 ERA and 138 strikeouts this season. Misiorowski is 1-1 with a 3.21 ERA and 20 strikeouts in his career against the Chicago Cubs.

Why the Milwaukee Brewers will win

• The Brewers have won each of their last nine games against National League opponents following a road win.
• The Cubs have lost each of their last four road games against the Brewers following a win.
• The Cubs have failed to cover the run line in each of their last five games as road underdogs against the Brewers following a win.
• The Brewers have covered the run line in each of their last five games against the Cubs following a win.
• The Cubs have trailed after 5 innings in each of their last four night games at American Family Field against National League opponents.

Why the Chicago Cubs will win

• The Cubs have won seven of their last eight road games against National League opponents.
• The Brewers have lost three of their last four games as home favorites against NL Central opponents following a road win.
• The underdogs have covered the run line in 10 of the Brewers’ last 11 games.
• The Brewers have failed to cover the run line in each of their last four games as favorites.

Total Runs Facts

• Each of the Brewers’ last four home games against NL Central opponents has gone UNDER the total runs line.
• Four of the Cubs’ last five games against National League opponents have gone OVER the total runs line.
• There has been at least one run scored in the first inning in eight of the Cubs’ last nine games as underdogs against NL Central opponents.
• There has been no run scored during the first inning in each of the Brewers’ last five games against NL Central opponents.

Milwaukee Brewers Player Prop Facts

• William Contreras has hit at least one home run in three of the Brewers’ last four games against the Cubs at American Family Field.
• Jacob Misiorowski has recorded a win in five of his last six appearances with the Brewers as favorites.
• Jacob Misiorowski has recorded nine or more strikeouts in each of his last five appearances at American Family Field.
• Garrett Mitchell has recorded at least one hit in each of his last nine appearances after not playing the previous day.
• Jacob Misiorowski ranks 1st amongst qualified players for Earned Run Average (1.45) this season.

Chicago Cubs Player Prop Facts

• Seiya Suzuki has hit a home run in each of the Cubs’ last two games at American Family Field.
• Alex Bregman has recorded at least one hit in each of the Cubs’ last 14 road games against opponents that held a winning record.
• Pete Crow-Armstrong ranks T7th in the league in Hits (88) this season.

Matchup/League Facts

• The Brewers rank 2nd in the league for ERA this season (3.38).
• The Brewers rank 2nd in the league for strikeouts this season (769).
• The Cubs rank 3rd in the league for on-base percentage this season (.337).
• The Cubs rank 6th in the league for runs scored this season (399).

Chicago Cubs vs Milwaukee Brewers Prediction

The Cubs and the big plus money are worth a look when you consider how good they are, but I can’t do it. Rea has been hittable with a 4.99 ERA and 1.40 WHIP, and he has a 7.19 ERA and .293 allowed batting average on the road. Misiorowski is one of the best young pitchers in baseball, and through 93 innings, he has a 1.45 ERA and 0.75 WHIP. Misiorowski has allowed 13 hits and 2 earned runs in his last 29 innings. At home, Misiorowski has a 1.58 ERA and a .147 allowed batting average. CY Young caliber stuff folks. I’m not betting against that. Give me the Brewers and the RL for max betting value.

Randy Chambers's Pick: Milwaukee Brewers -1.5