Chicago Cubs vs Cincinnati Reds Prediction 7/10/2026 Today’s MLB Picks

In this article, we will formulate a Cubs vs Reds Prediction for this MLB matchup on Friday, July 10th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Preview

The Cincinnati Reds have a 42-50 record this season and are sitting in the 5th place of the NL Central. They have a 21-26 home record and are coming off a 0-1 home loss against the Phillies. They will face the Rockies and the Mariners next.

The Cincinnati Reds have a .227 batting average this season, .309 OBP and .389 Slugging percentage. Cincinnati’s pitching staff has a 4.53 ERA and 1.45 WHIP. Elly De La Cruz is the team’s best hitter with a .270 batting average. Sal Stewart leads the team in RBI with 64, adding a team-high 19 home runs.

Hunter Greene (R) is the projected starting pitcher for the Cincinnati Reds, and he has a 0-1 record, 21.60 ERA and 3.30 WHIP.

Chicago Cubs Preview

The Chicago Cubs have a 52-41 record this season and are sitting in the 2nd place of the NL Central. They have a 25-22 away record and are coming off a 9-7 road win against the Orioles. They will face the Twins and the Tigers next.

The Chicago Cubs have a .244 batting average this season, .337 OBP and .412 Slugging percentage. Chicago’s pitching staff has a 4.35 ERA and 1.27 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .296 batting average. He also adds a team-high 21 home runs, while Dansby Swanson leads the team in RBI with 58.

Shota Imanaga (L) is the projected starting pitcher for the Chicago Cubs, and he has a 5-7 record, 4.28 ERA and 1.10 WHIP.

The Chicago Cubs @ Cincinnati Reds Betting Trends: July 10, 2026

• Probable Starting Pitcher: Hunter Greene      Record this season: 0-1      ERA: 21.60
• Home Record: 0-1
• Last 5 against Cubs: 2-0

Why the Cincinnati Reds will win

• The home team has won each of the last nine games between the Cubs and Reds.
• The Cubs have lost six of their last eight games as favorites against NL Central opponents.
• The Reds have covered the run line in each of their last six games as home underdogs against the Cubs following a home loss.
• The Cubs have failed to cover the run line in 13 of their last 16 games as favorites against NL Central opponents.
• The Cubs have trailed after 3 innings in five of their last six games at Great American Ball Park against opponents that held a losing record.
• The Reds have won the first inning in each of their last five games as underdogs against the Cubs at Great American Ball Park.
• The Cubs have trailed after 5 innings in six of their last seven games at Great American Ball Park.

• Probable Starting Pitcher: Shota Imanaga      Record this season: 5-7      ERA: 4.28
• Road Record: 2-3
• Last 5 against Reds: 2-0

Why the Chicago Cubs will win

• The Cubs have won each of their last eight games against NL Central opponents that held a losing record.
• The Reds have lost nine of their last 10 night games after playing the previous day.
• The Cubs have covered the run line each of their last six games against NL Central opponents that held a losing record.
• The Reds have failed to cover the run line in four of their last five games against NL Central opponents.
• The Cubs have led after 5 innings in seven of their last eight night games against NL Central opponents that held a losing record.
• The Reds have trailed after 3 innings in four of their last five games as home underdogs against NL Central opponents.
• The Cubs have won the first inning in four of their last five games against NL Central opponents that held a losing record.

Total Runs Facts

• Each of the Reds’ last six night games as underdogs have gone UNDER the total runs line.
• Four of the Cubs’ last five games against National League opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in each of the Reds’ last seven home games against National League opponents.
• There has been no run scored during the first inning in 10 of the Cubs’ last 11 road games.

Cincinnati Reds Player Prop Facts

• Eugenio Suarez has hit at least one home run in three of his last four home appearances against the Cubs.
• Hunter Greene has recorded seven or more strikeouts in each of his last five home appearances.
• Elly De La Cruz has recorded at least one hit in each of his last 10 appearances with the Reds as home underdogs against NL Central opponents.
• Hunter Greene has recorded a win in four of his five previous home appearances against the Cubs.

Chicago Cubs Player Prop Facts

• Pete Crow-Armstrong has hit at least one home run in four of the Cubs’ last five night games against NL Central opponents that held a losing record.
• Shota Imanaga has recorded seven or more strikeouts in three of his four previous appearances against the Reds.
• Pete Crow-Armstrong has recorded at least one hit in each of the Cubs’ last 18 games as favorites.
• Pete Crow-Armstrong is one of only two players to record 10+ Home Runs and 4+ Triples this season.

Matchup/League Facts

• The Reds rank 29th in the league for hits this season (698).
• The Reds rank 29th in the league for batting average this season (.227).
• The Cubs rank 1st in the league for walks this season (406).
• The Cubs rank 29th in the league for home runs allowed this season (142).

Cubs vs Reds Prediction

The Cubs have won their last four meetings against the Reds but have lost all of their last four visits in Cincinnati.

In this Cubs vs Reds Prediction, both teams are coming at a pickem price. I like the Cubs in this one at a pickem price as they have every advantage you can think of. They have the pitching edge with Imanaga on the mound, who has been better on the road and a better expected ERA, while Greene was torched in his first start of the season for the Reds. The Cubs also have a better bullpen and are 8th against right-handed pitching in the month of July, while the Reds are just 24th against lefties. Take the Cubs to win this one on the road.

Nikos Lagouretos's Pick: Chicago Cubs ML