Chicago Cubs vs Arizona Diamondbacks Prediction 3/30/25 MLB Picks

The Chicago Cubs and Arizona Diamondbacks meet Sunday in MLB action at Chase Field. Here’s a Chicago Cubs vs Arizona Diamondbacks Prediction. This article will include a Chicago Cubs vs Arizona Diamondbacks Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 2-3 on the year and play the Athletics, Padres, and Rangers next. The Cubs look for back-to-back wins for the first time this season as the offense continues to come and go. The Cubs have scored 14 runs in their two wins and five runs in their three losses. The Cubs have won seven of their last eight games when scoring more than three runs. Kyle Tucker leads the Chicago Cubs with 5 hits and 4 RBI, while Ian Happ and Jon Berti have combined for 8 hits and 4 RBI.

Matthew Boyd gets the ball for the Cubs, and he was 2-2 with a 2.72 ERA and 46 strikeouts last season. Matz is 0-2 with a 6.55 ERA and 9 strikeouts in his career against the Arizona Diamondbacks.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 1-2 on the year and play the Yankees, Nationals, and Orioles next. The Diamondbacks look to get back to a .500 record after coming up just short in Saturday’s loss. The Diamondbacks are letting the Cubs off the hook in these games and need a feel-good win before leaving for the Bronx on Tuesday. Ketel Marte leads the Arizona Diamondbacks with 5 hits and 0 RBI, while Eugenio Suarez and Josh Naylor have combined for 8 hits and 9 RBI.

Eduardo Rodriguez gets the ball for the Arizona Diamondbacks, and he was 3-4 with a 5.04 ERA and 47 strikeouts last season. This will be Rodriguez’s second career game against the Chicago Cubs.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won 14 of their last 15 games against NL Central opponents following a home loss.
• The Cubs have lost each of their last four road games against National League opponents following a win.
• The Cubs have failed to cover the run line in each of their last five games as underdogs against National League opponents following a win.
• The Diamondbacks have covered the run line in five of their last six day games against National League opponents following a loss.
• The Cubs have trailed after 5 innings in each of their last four games at Chase Field against NL West opponents that held a losing record.
• The Cubs have trailed after 3 innings in three of their last four games at Chase Field against NL West opponents that held a losing record.

Why the Chicago Cubs will win

• The underdogs have won nine of the last 11 games between the Cubs and Diamondbacks at Chase Field.
• The Diamondbacks have lost eight of their last 12 games as home favorites.
• The underdogs have covered the run line in 12 of the last 13 games between the Cubs and Diamondbacks at Chase Field.
• The Diamondbacks have failed to cover the run line in 13 of their last 15 home games against NL Central opponents.
• The Cubs have led after 5 innings in each of their last three road day games.

Chicago Cubs vs Arizona Diamondbacks Prediction

I’m not excited with a pitching matchup of Matthew Boyd and Eduardo Rodriguez, but I’m going to lean toward the Diamondbacks and the cheap price. The Diamondbacks are simply the better team no matter how you slice it and it’s only a matter of time before they put together a complete performance. I’d need more plus money to look in the Cubs direction and we’re just not getting it in this spot. Rodriguez is better than what he showed last season and Boyd has just never moved the needle for me. Give me the Diamondbacks and the soft line.