Brewers vs Pirates Prediction 9/17/2026 Today’s MLB Picks

In this article we will formulate a Brewers vs Pirates prediction for this MLB game on Thursday, September 17th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 95-57 this season after they won the first two games by scores of 5-1 and 5-4. In game two, Milwaukee blew a 3-1 lead, but they scored twice in the seventh to get the win. The Brewers recorded 10 hits in the game and they were led by Yelich, who went 1-5 with two RBIs. Henderson allowed six hits and three earned runs over 5.0 innings, while Senzatela got the win and Megill picked up the save. Prior to this series, Milwaukee won two out of three against the Reds and all three against the Cubs. 

This season, Milwaukee has a 3.56 ERA with a 1.19 WHIP and a .224 opponent batting average, while they have scored 788 runs with a .259 batting average and a .341 on base percentage. Jake Bauers has led the Brewers with 26 home runs and 83 RBIs, while Brice Turang has added 19 home runs and 93 RBIs. The projected starting pitcher for Milwaukee is Kyle Harrison, who is 10-4 with a 3.98 ERA and a 1.31 WHIP over 110.2 innings pitched this season. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 75-77 this year after they lost game two by a score of 4-5 on Wednesday night. Pittsburgh took the 4-3 lead in the sixth inning, but the bullpen fell apart for another late loss. The Pirates recorded 12 hits in the game and they were led by Lowe, who went 2-3 with one home run and two RBIs. Jones allowed seven hits and three earned runs over 5.0 innings, while Mlodzinski picked up the loss in relief. Prior to this series, Pittsburgh lost two out of three against the Cubs, but did sweep the White Sox in three games before that. 

This season, Pittsburgh has a 4.19 ERA with a 1.30 WHIP and a .237 opponent batting average, while they have scored 723 runs with a .253 batting average and a .330 on base percentage. Brandon Lowe has led the Pirates with 31 home runs and 88 RBIs, while Ryan O’Hearn has added 18 home runs and 72 RBIs. The projected starting pitcher for Pittsburgh is Wilber Dotel, who is 1-5 with a 4.84 ERA and a 1.36 WHIP over 35.1 innings pitched this year. 

Why the Pittsburgh Pirates will win

• The Brewers have lost 10 of their last 18 games as road favorites against NL opponents.
• The Pirates have won five of their last six games at PNC Park following a loss.
• The Brewers have failed to cover the run line in eight of their last nine games as road favorites against NL Central opponents following a road win.
• The Pirates have covered the run line in each of their last five games as underdogs following a loss.

Why the Milwaukee Brewers will win

• The Brewers have won seven of their last eight games against NL Central opponents.
• The Pirates have lost each of their last four home games against NL opponents that held a winning record.
• The Brewers have covered the run line in nine of their last 10 games against the Pirates following a win.
• The Pirates have failed to cover the run line in six of their last seven games at PNC Park against NL opponents that held a winning record.
• The Pirates have trailed after 3 innings in five of their last six games against NL opponents that held a winning record.
• The Brewers have led after 5 innings in five of their last six games as favorites.

Total Runs Facts

• Five of the Pirates’ last six home games have gone UNDER the total runs line.
• Nine of the Brewers’ last 11 road games after playing the previous day have gone OVER the total runs line.
• There has been no run scored during the first inning in eight of the Pirates’ last nine home games against NL Central opponents.
• There has been at least one run scored in the first inning in each of the Brewers’ last six Thursday day games against NL opponents.

Pittsburgh Pirates Player Prop Facts

• Rafael Flores has recorded at least one hit in each of the Pirates’ last nine games as underdogs.
• Brandon Lowe has hit a home run in each of the Pirates’ last three games as underdogs against the Brewers.
• Nick Gonzales is one of only six players to hit over .300 and have 45+ RBIs this season.

Milwaukee Brewers Player Prop Facts

• William Contreras has hit a home run in three of his last four appearances against NL Central opponents that held a losing record.
• Kyle Harrison has recorded seven or more strikeouts in each of his three previous appearances against the Pirates.
• Jake Bauers has recorded at least one hit in each of his last eight appearances against the Pirates after playing the previous day.

Matchup/League Facts

• The Pirates rank 4th in the league for on-base percentage this season (.330).
• The Pirates rank 27th in the league for strikeouts against this season (1418).
• The Brewers rank 2nd in the league for runs scored this season (788).
• The Brewers rank T29th in the league for home runs this season (146).

Brewers vs Pirates Prediction 

Milwaukee comes into this matchup looking for the series sweep and they have won four of their last five games. The Brewers are 43-31 on the road this year, while the Pirates are 38-36 at home. Pittsburgh has dropped four of their last five games and they have allowed 5+ in three of those five. The Pirates are starting Dotel, who will be an opener, while Harrison has allowed 4, 4, and 9 earned runs in his last three starts. Take the Pirates to win here.

David Racey's Pick: Pirates ML