Athletics vs Cincinnati Reds Prediction 8/5/2026 Today’s MLB Picks

The Athletics and the Cincinnati Reds meet Wednesday in MLB action from Great American Ballpark. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Athletics vs. Cincinnati Reds prediction.

Starting Pitching Matchup

The Athletics will start Jacob Lopez here and Lopez is 5-4 with a 5.79 ERA and 61 strikeouts this season. Rhett Lowder will start for the Reds and is 3-7 with a 5.42 ERA and 70 strikeouts this season.

Athletics Recap

The Athletics come into this game looking to bounce back from a 5-4 loss at the hands of the Reds on Tuesday to sit at 45-68 this season. After this series, the Athletics will head on the road for a series against the Boston Red Sox.

Athletics Lose 6 Straight & 9 Of Last 10

Going into Tuesday, Shea Langeliers has 99 hits with 19 doubles, 23 home runs and 51 RBIs while Tyler Soderstrom’s added 88 hits with 24 doubles, 2 triples, 17 home runs and 50 RBIs. Jacob Wilson also has 79 hits with 12 doubles, 7 home runs and 34 RBIs and Nick Kurtz has 90 hits with 15 doubles, 21 home runs and 69 RBIs this season.

Cincinnati Reds Recap

The Cincinnati Reds come into this game looking to add on to their win over the A’s from Tuesday to sit at 54-58 this season. After this series, the Reds will head on the road for a series against the Washington Nationals.

Reds Win 4 Of Last 5

Entering Tuesday, Elly De La Cruz has 101 hits with 18 doubles, 4 triples, 18 home runs and 50 RBIs while Sal Stewart has 107 hits with 23 doubles, 24 home runs and 85 RBIs. Spencer Steer has 81 hits with 14 doubles, 16 home runs and 40 RBIs and Matt McLain has 53 hits with 13 doubles, 8 home runs and 26 RBIs. JJ Bleday’s added 67 hits with 11 doubles, 19 home runs and 46 RBIs as well on the year.

Athletics @ Cincinnati Reds Betting Trends: August 5, 2026

• Probable Starting Pitcher: Rhett Lowder      Record this season: 3-7      ERA: 5.42
• Home Record: 1-1
• Last 5 against Athletics: –

Why the Cincinnati Reds will win

• The Athletics have lost each of their last six games.
• The home team has won each of the last five games between the Athletics and Reds.
• The Athletics have failed to cover the run line in seven of their last eight night games against NL Central opponents that held a losing record.
• The Reds have covered the run line in five of their last six games as favorites against AL West opponents following a win.
• The Athletics have trailed after 3 innings in four of their last five road games against NL Central opponents that held a losing record.
• The Athletics have trailed after 5 innings in four of their last five games against opponents that held a losing record.

• Probable Starting Pitcher: Jacob Lopez      Record this season: 5-4      ERA: 5.79
• Road Record: 5-1
• Last 5 against Reds: –

Why the Athletics will win

• The Reds have lost six of their last seven games as home favorites following a win.
• The Athletics have won each of their last five Wednesday games as road underdogs against NL Central opponents.
• The Reds have failed to cover the run line each of their last 10 night games against American League opponents that held a losing record.
• The Athletics have covered the run line in each of their last nine games against the Reds.
• The Reds have lost the first inning in three of their last four games as favorites against American League opponents.
• The Athletics have led after 3 innings in four of their last five night games against the Reds.
• The Reds have trailed after 5 innings in six of their last eight night games against American League opponents that held a losing record.

Total Runs Facts

• Five of the Reds’ last six night games after playing the previous day have gone UNDER the total runs line.
• Four of the Athletics’ last five games as underdogs against the Reds have gone OVER the total runs line.
• There has been no run scored during the first inning in seven of the Athletics’ last eight road games against National League opponents.
• There has been no run scored during the first inning in each of the Reds’ last four home games against AL West opponents.

Cincinnati Reds Player Prop Facts

• Elly De La Cruz has recorded at least one hit in each of the Reds’ last nine games as favorites.
• Jose Trevino has hit at least one home run in each of his last two appearances against opponents that held a losing record.
• Elly De La Cruz is one of only 10 players to record 10+ Home Runs and 4+ Triples this season.

Athletics Player Prop Facts

• Lawrence Butler has hit at least one home run in three of the Athletics’ last four road games against the Reds.
• Jacob Lopez has recorded a win in six of his last eight road appearances against opponents that held a losing record.
• Tyler Soderstrom has recorded at least one hit in each of the Athletics’ last 13 games as road underdogs against NL opponents.

Matchup/League Facts

• The Reds rank 30th in the league for hits this season (860).
• The Reds rank 30th in the league for batting average this season (.230).
• The Athletics rank 30th in the league for home runs allowed this season (176).
• The Athletics rank 29th in the league for ERA this season (5.42).

Athletics vs. Cincinnati Reds Prediction

I’m backing Cincinnati here. Rhett Lowder isn’t the best starting option for the Reds to put out, but there’s a significant edge that the Reds have in bullpen pitching right now as the Athletics have the worst bullpen ERA over the last month. Even if Lopez pitches well, this Athletics bullpen is more than prone to giving it up so give me the Reds.

Chris Ruffolo's Pick: Cincinnati -145