Athletics vs Chicago White Sox Prediction 7/10/2026 Today’s MLB Picks

The Athletics and the Chicago White Sox meet Friday in MLB action from Rate Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Athletics vs. Chicago White Sox prediction.

Starting Pitching Matchup

The Athletics will send out Jacob Lopez for the start here and Lopez is 4-3 with a 7.04 ERA and 42 strikeouts this season. Sean Burke will start for Chicago and is 5-4 with a 3.56 ERA and 106 strikeouts this season.

Athletics Recap

The Athletics come into this game looking to bounce back from a 4-1 loss at the hands of the Detroit Tigers last time out to sit at 41-52 this season. After this series, the Athletics will head home for a series against the Washington Nationals.

Athletics Lose 6 In A Row

Shea Langeliers has 89 hits with 16 doubles, 20 home runs and 45 RBIs while Tyler Soderstrom’s added 71 hits with 21 doubles, 2 triples, 13 home runs and 41 RBIs. Brent Rooker has 36 hits with 10 home runs and 29 RBIs. Jacob Wilson also has 58 hits with 10 doubles, 4 home runs and 26 RBIs and Nick Kurtz has 89 hits with 15 doubles, 20 home runs and 66 RBIs this season.

Chicago White Sox Recap

The Chicago White Sox come into this game looking to bounce back from a 2-1 loss at the hands of the Boston Red Sox last time out to sit at 47-45 this season. After this series, the White Sox will head on the road for a series against the Toronto Blue Jays.

White Sox Lose 3 In A Row

Munetaka Murakami has 48 hits with 20 home runs and 41 RBIs while Miguel Vargas has 79 hits with 17 doubles, a triple, 20 home runs and 56 RBIs and Colson Montgomery has 73 hits with 16 doubles, 23 home runs and 53 RBIs. Luisangel Acuna has 34 hits and Tristan Peters has 70 hits with 19 doubles and 31 RBIs so far this season. Chase Meidroth also has 89 hits with 15 doubles, 7 home runs and 29 RBIs this year.

Athletics @ the Chicago White Sox Betting Trends: July 10, 2026

• Probable Starting Pitcher: Sean Burke      Record this season: 5-4      ERA: 3.56
• Home Record: 1-3
• Last 5 against Athletics: 1-2

Why the Chicago White Sox will win

• The White Sox have won each of their last seven games against AL West opponents following a home loss.
• The Athletics have lost 12 of their last 13 road games against AL Central opponents that held a winning record.
• The Athletics have failed to cover the run line in each of their last seven games as underdogs against American League opponents.
• The White Sox have covered the run line in each of their last six games against the Athletics.
• The Athletics have lost the first inning in three of their last four games.
• The Athletics have trailed after 5 innings in each of their last seven games as underdogs against American League opponents.
• The Athletics have trailed after 3 innings in each of their last six games.

• Probable Starting Pitcher: Jacob Lopez      Record this season: 4-3      ERA: 7.04
• Road Record: 4-1
• Last 5 against White Sox: –

Why the Athletics will win

• The Athletics have won each of their last three games as underdogs against the White Sox following a loss.
• The White Sox have lost three of their last four games as favorites after playing the previous day.
• The road team has covered the run line in each of the last nine games between the Athletics and White Sox.
• The White Sox have failed to cover the run line in each of their last six games as favorites after playing the previous day.
• The Athletics have won the first inning in six of their last eight games against American League opponents that held a winning record.
• The White Sox have trailed after 5 innings in each of their last four home games.
• The White Sox have trailed after 3 innings in four of their last five night games.

Total Runs Facts

• Seven of the Athletics’ last eight games as underdogs against the White Sox have gone OVER the total runs line.
• Five of the last six games between the Athletics and White Sox have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of the White Sox’s last six night games against AL West opponents.
• There has been no run scored during the first inning in eight of the Athletics’ last 10 road games.

Chicago White Sox Player Prop Facts

• Colson Montgomery has hit a home run in each of the White Sox’s last two games against the Athletics.
• Sean Burke has recorded six or more strikeouts in each of his last eight appearances.
• Miguel Vargas has recorded at least one hit in each of the White Sox’s last eight home games against AL West opponents.
• Colson Montgomery ranks 9th in the league in Home Runs (23) this season.

Athletics Player Prop Facts

• Nick Kurtz has hit a home run in each of the Athletics’ last three night games against AL opponents that held a winning record.
• Zack Gelof has recorded at least one hit in each of his last 11 appearances against opponents that held a winning record.
• Jacob Lopez has recorded five or more strikeouts in five of his six previous appearances against AL Central opponents.
• Jacob Lopez has recorded a win in three of his four previous road appearances against AL Central opponents.
• Nick Kurtz ranks 3rd amongst qualified players for On Base Percentage (.405) this season.

Matchup/League Facts

• The White Sox rank 4th in the league for home runs this season (125).
• The White Sox rank T25th in the league for triples this season (7).
• The Athletics rank 30th in the league for home runs allowed this season (146).
• The Athletics rank 29th in the league for ERA this season (5.12).

Athletics vs. Chicago White Sox Prediction

I’m on the White Sox in this one. I do have concerns about the form of both teams in this game, but the White Sox are supposed to get Murakami back for this game and I feel like I can trust Sean Burke as one of the more reliable options in this White Sox rotation. The Athletics are talented but just look lost right now at the plate and I think the White Sox draw first blood here. Give me Chicago.

Chris Ruffolo's Pick: Chicago -125