San Francisco Giants vs Los Angeles Angels Prediction 4/18/25 MLB Picks

Los Angeles Angels (9-9) vs San Francisco Giants (13-6)

Game Info: Friday, April 18, 2025 at 9:38 pm (Angel Stadium)

L. Webb (R) vs T. Anderson (L)

Betting Odds: Los Angeles Angels +130 / San Francisco Giants -155 --- Over/Under: 8 Click Here for the Latest Odds

Where to Watch: MLBN

The San Francisco Giants and Los Angeles Angels meet Friday in MLB action at Angel Stadium. Here’s a San Francisco Giants vs Los Angeles Angels Prediction. This article will include a San Francisco Giants vs Los Angeles Angels Pick.

San Francisco Giants Betting Preview

The San Francisco Giants are 13-6 on the year and play the Brewers, Rangers, and Padres next. The San Francisco Giants are batting .231 on the season, have a .308 OBP, and a .415 slugging percentage. The San Francisco Giants pitching staff has a 3.63 ERA and a 1.28 WHIP. Jung Hoo Lee leads the San Francisco Giants with 24 hits and 14 RBI, while Heliot Ramos and Tyler Fitzgerald have combined for 35 hits and 15 RBI. 

Logan Webb gets the ball for the San Francisco Giants, and he is 2-0 with a 2.63 ERA and 26 strikeouts this season. This will be Webb’s second career game against the Los Angeles Angels.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 9-9 on the year and play the Pirates, Twins, and Mariners next. The Los Angeles Angels are batting .230 on the season, have a .292 OBP, and a .419 slugging percentage. The Los Angeles Angels pitching staff has a 4.76 ERA and a 1.40 WHIP. Nolan Schanuel leads the Los Angeles Angels with 19 hits and 7 RBI while Taylor Ward and Jorge Soler have combined for 36 hits and 17 RBI.

Tyler Anderson gets the ball for the Los Angeles Angels, and he is 1-0 with a 2.87 ERA and 15 strikeouts this season. Anderson is 4-3 with a 4.09 ERA and 55 strikeouts in his career against the San Francisco Giants.

Why the Los Angeles Angels will win

  • The Angels have won each of their last five games as underdogs against NL West opponents following a loss.
  • The Giants have lost four of their last five Friday night games as favorites against AL West opponents.
  • The Angels have covered the run line in each of their last five games as underdogs against NL West opponents following a loss.
  • The Giants have failed to cover the run line in seven of their last eight Friday night games as favorites against American League opponents.

Why the San Francisco Giants will win

  • The Giants have won each of their last seven night games against American League opponents.
  • The Angels have lost each of their last four games.
  • The Giants have covered the run line in each of their last eight road games against American League opponents following a loss.
  • The Angels have failed to cover the run line each of their last four games against teams that held a winning record.
  • The Angels have trailed after 5 innings in each of their last six Friday night games against NL West opponents that held a winning record.
  • The Angels have trailed after 3 innings in five of their last six night games against NL West opponents.

Matchup/League Facts

  • The Angels rank 28th in the league for ERA this season (4.76).
  • The Angels rank 28th in the league for strikeouts this season (131).
  • The Giants rank T3rd in the league for triples this season (4).
  • The Giants rank 28th in the league for strikeouts against this season (186).

San Francisco Giants vs Los Angeles Angels Prediction

Right when it looked like the Angels were playing good ball and possibly turning the corner, they lose four straight games and get outscored 7-19 during that span. Looks like we’re back to fading the Angels. The Giants have been a solid team through 19 games and even recent losses to the Phillies were competitive. Webb is one of the more underrated pitchers in baseball and he’s dealing right now, allowing 20 hits and seven runs through 24 innings while striking out 26. Through 59 at bats against current Angels, Webb is allowing a .169 batting average with 24 strikeouts. Give me the Giants and the somewhat reasonable price. 

Randy’s Pick San Francisco Giants -155

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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