Boston Red Sox vs Chicago White Sox Prediction 4/11/25 MLB Picks

Chicago White Sox (2-10) vs Boston Red Sox (7-7)

Game Info: Friday, April 11, 2025 at 7:40 pm (Rate Field)

S. Newcomb (L) vs D. Martin (R)

Betting Odds: Chicago White Sox +145 / Boston Red Sox -175 --- Over/Under: 8 Click Here for the Latest Odds

Where to Watch: MLB.TV

In this article, we will formulate a Red Sox vs White Sox prediction for this MLB game on Friday, April 11, at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup.

Boston Red Sox Betting Preview

The Boston Red Sox (7-7, 3-4 Away) were on a positive run of five wins, but then they lost three in a row to the Toronto Blue Jays. The Red Sox managed to salvage the series with a 4-3 extra-inning victory and now will spend the next two series on the road. Walker Buehler was solid in 6.1 innings of work, as he allowed one run on four hits with seven strikeouts and one walk. Brennan Bernardino was credited with a win.

This year, the Red Sox average 5.15 runs per game (6th in the MLB) on a .257/.330/.397 triple-slash. When it comes to pitching, the Red Sox’s staff has a 4.03 ERA (16th) and 1.36 WHIP (24th). Wilyer Abreu leads the Red Sox with a .350 batting average, three home runs, and 12 RBI this season.

Sean Newcomb will take the mound for the Red Sox on Friday. The 31-year-old left-hander has a 0-1 record in two starts this year with a 5.19 ERA and 2.19 WHIP over 8.2 innings of work.

Chicago White Sox Betting Preview

The Chicago White Sox (2-10, 2-4 Home) won two of the opening four games this season and then lost each of the following eight. The White Sox lost the series to the Angels and Twins and have been swept by the Tigers and Guardians. In the latest 6-1 defeat to Cleveland, Jonathan Cannon took a loss after allowing six runs on seven hits with six strikeouts and three walks in 5.1 innings.

This season, the White Sox average 3.09 runs per game (29th in the MLB) on a .202/.276/.315 slash line. Regarding pitching, the White Sox’ staff has a 3.72 ERA (13th) and 1.26 WHIP (14th). Andrew Benintendi leads the White Sox with a .290 batting average, two home runs, and six RBI this season.

The projected starting pitcher for the White Sox is Davis Martin, who has a 0-1 record in two starts this year with a 5.73 ERA and 1.55 WHIP in 11.0 innings.

Total Runs Facts

  • Each of the Red Sox's last eight night games against American League opponents have gone UNDER the total runs line.
  • Four of the White Sox's last five night games against AL East opponents have gone OVER the total runs line.
  • The 'Inning 1 UNDER 0.5 runs' market has hit in seven of the White Sox's last eight night games.
  • The 'Inning 1 UNDER 0.5 runs' market has hit in seven of the Red Sox's last eight games as favorites against American League opponents.

Matchup/League Facts

  • The White Sox rank 29th in the league for RBIs this season (33).
  • The White Sox rank 29th in the league for batting average this season (.199).
  • The Red Sox rank 2nd in the league for doubles this season (29).
  • The Red Sox rank 29th in the league for hits allowed this season (129).

Red Sox vs White Sox Prediction

The teams have traded wins in the past few years, as each recorded five in the previous ten H2H duels. Boston was better in three of the last four. Just like last season, the White Sox are struggling against southpaws, with a .186 BA and only four RBI in 59 at-bats. Newcomb and Martin weren't impressive in their early starts, but I am looking for an improvement here, especially from Newcomb. A combination of poor hitting against lefties and the worst offense in the MLB is enough for me to back Under in this one.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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