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New York Mets vs Houston Astros Prediction 3/27/25 MLB Picks

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Houston Astros (0-0) vs New York Mets (0-0)

March 27, 2025 at 04:10 PM EDT

The Line: Mets +114 / Astros -135 // Total: 8

(Get latest betting odds)

In this article, we will formulate a New York Mets vs Houston Astros  Prediction for this MLB game on Thursday, March 27th  at the Minute Maid Park. To formulate this prediction, we will look at: 

-The Mets’ recent form and recent player performance 

-The Astros’ recent form and recent player performance

-Recent Betting trends and streaks involving New York

-Recent Betting trends and streaks involving Houston

-Recent betting trends in games played between New York and Houston

-A summary that ties it all together produces a favorable betting outcome for Today’s Game between the Mets and Astros. 

Soto Era Begins for the Mets

The Juan Soto era is beginning for the Mets, and with all the money on the payroll, this team should compete for the World Series, or this season will be a major disappointment. Francisco Lindor, Soto, Pete Alonso, and Mark Vientos are a great top four of the lineup, but the big question concerns the pitching staff. For all the money spent on the Mets lineup, they seemed to forget about the rotation, and this might be a team that needs to win games 9-8. 

Catcher Frankie Alvarez fractured his left hamate bone in early March, and he’s going to be out for at least a couple more weeks. Clay Holmes is going to get the start here for the Mets, and I’m not sure that should give the team that much confidence in the long term that he’s the ace. Last year with the New York Yankees, he finished with a 3-5 record while sitting with an ERA of 3.14. During spring training, he finished with a 1-1 record, and he had an ERA of 0.93. 

Big Changes for the Astros

There were some big changes for the Astros this offseason. The big question is whether the dynasty is finally over. Jose Altuve is back, but many of the teams that had World Series success are gone. Kyle Tucker was traded to the Chicago Cubs during the offseason. The good news for the Astros is that this team still has a ton of talent. This squad still has Yordan Alvarez, and last season, he was dominant, hitting 35 home runs while racking up 86 RBIs. 

Getting the start for the Astros will be Framber Valdez, and he needs to be dominant here. Valdez finished last season with a 15-7 record and an ERA of 2.91.  Valdez finished the preseason with a 2-0 record, and he had an ERA of 3.45.  Josh Hader is the closer for this team, and the hope is they will use him in this game. 

Why the Astros Will Beat the Mets

  • The Mets have lost seven of their last eight games against AL West opponents.
  • The Astros have won each of their last six Thursday games at Daikin Park.
  • The Astros have covered the run line in 10 of their last 11 home games against the Mets.
  • The Mets have failed to cover the run line in nine of their last 10 day games against AL West opponents.
  • The Mets have trailed after 5 innings in each of their last five road games against AL West opponents.
  • The Astros have led after 3 innings in four of their last five games as home favorites against NL East opponents.

New York Mets vs Houston Astros Prediction

The Astros are going to have no issue getting the job done here. The Mets’ offense is going to be fine this season, but not against Framber Valdez. Last season, Valdez had an ERA of 2.91, and he’s going to start the season strong. Having Hader on the back end of the bullpen is also going to be key. Clay Homles shouldn’t be the day one starter for this team, and the pitching for the Mets is going to end up holding them back. The Astros’ offense will run up the scor,e and they will pick up the opening day win.

Shane Mickle's Pick: Houston Astros ML -135

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