Sep 26, 2026; Raleigh, North Carolina, USA;  NC State Wolfpack running back Jayden Scott (1) celebrates a touchdown during the first half of the game against App State Mountaineers at Carter-Finley Stadium.  Mandatory Credit: Jaylynn Nash-Imagn Images
IMAGN IMAGES via Reuters Connect

Louisville vs NC State Prediction 10/3/2026 Today’s College Football Picks

Pick details

MATCHUP Louisville Cardinals NC State Wolfpack
Team Records 2-2 2-2
Spread -3.5 -112 +3.5 -108
Moneyline -185 +154
Total Over 58.5 (-110) Under 58.5 (-110)
Where Carter-Finley Stadium, Raleigh, NC
When Saturday, October 3, 2026
Time 03:30 PM EDT
TV ACC Network

The Louisville Cardinals and NC State Wolfpack meet Saturday in week 5 college football action at Carter-Finley Stadium. Here’s a Louisville vs. NC State Prediction. This article will include a Louisville vs. NC State Pick.

Louisville Cardinals Betting Preview


The Louisville Cardinals beat SMU, lost to Wake Forest, and they play Florida State next. Louisville has won 4 of its last 6 games. Lincoln Kienholz is completing 68.8 percent of his passes for 1,140 yards, 7 touchdowns, and 1 interception. Tre Richardson and Lawayne McCoy have combined for 629 receiving yards and 4 touchdowns, while Jaleel Skinner has 12 receptions.

The Louisville Cardinals’ ground game is averaging 190.5 yards per contest, and Keyjuan Brown leads the way with 279 yards and 2 touchdowns. Defensively, Louisville is allowing 28.8 points and 405.5 yards per game. Stanquan Clark leads the Louisville Cardinals with 28 tackles, Clev Lubin has 2.5 sacks, and Kaleb Beasley has 2 interceptions.

NC State Wolfpack Betting Preview


The NC State Wolfpack lost to Vanderbilt, beat App State, and plays Wake Forest next. NC State has won 6 of its last 10 games. CJ Bailey is completing 67.3 percent of his passes for 893 yards, 6 touchdowns, and 3 interceptions. Keenan Jackson and Preston Douglas have combined for 462 receiving yards and 5 touchdowns, while Joshisa Trader has 11 receptions.

The NC State Wolfpack ground game is averaging 219 yards per contest, and Jayden Scott leads the way with 346 yards and 4 touchdowns. Defensively, NC State is allowing 25 points and 327.8 yards per game. Popo Aguirre leads the NC State Wolfpack with 36 tackles, Elijah Satchell has 2 sacks, and Jackson Vick has 1 interception.

Why the NC State Wolfpack will win

  • NC State has won eight of its last nine games at Carter-Finley Stadium.
  • Louisville has lost four of its last six October games as a road favorite against non-AP-ranked teams.
  • Louisville has failed to cover the spread in each of its last eight October games as a road favorite against non-AP-ranked teams.
  • NC State has covered the spread in four of its last five home games against conference opponents.
  • Louisville has lost the first half in five of its last six games as a favorite in North Carolina.

Why the Louisville Cardinals will win

  • Louisville has won five of its last six games against teams from North Carolina.
  • The favorite has covered the spread in four of the last five games between Louisville and NC State.
  • NC State has failed to cover the spread in seven of its last nine October games as an underdog.
  • Louisville has won the first half in three of its last four games against non-AP-ranked teams.

Total Points Facts

  • Each of Louisville’s last four games as a favorite against teams from North Carolina have gone UNDER the total points line.
  • Six of NC State’s last seven games against teams from Kentucky have gone UNDER the total points line.

NC State Wolfpack Player Prop Facts

  • Heading into Week 5, Keenan Jackson ranks T12th amongst FBS players for receiving touchdowns (4) this season.

Louisville Cardinals Player Prop Facts

  • Heading into Week 5, Keyjuan Brown ranks 4th amongst qualified players for Yards Per Carry (9.3) this season.

Matchup/League Facts

  • NC State ranks 10th among FBS teams for 3rd down conversion percentage this season (53.6).
  • NC State ranks T128th among FBS teams for average point differential in fourth quarters this season (-4.5).
  • Louisville ranks T4th among FBS teams for Q3 points per game this season (13.0).
  • Louisville ranks T5th among FBS teams for H2 points per game this season (23.3).

Louisville vs NC State Prediction


Louisville is the more complete team, and this is probably a good spot to back the Cardinals after a horrendous performance against Wake Forest. However, Louisville lost to Wake Forest as a double-digit favorite. We don’t just ignore that. I also love my hooks on top of key numbers, and we’re getting points with an NC State team that’s led by a difference maker at quarterback. There’s not a lot of star QBs in the country, and NC State has one that can completely take over a game. Basically, NC State is live every week. I’ll grab the points with the Wolfpack.

Randy Chambers's Pick: NC State +3.5

Hot Cappers