Oct 17, 2026; Clemson, South Carolina, USA;  Clemson Tigers quarterback Brock Bradley (5) hands the ball off to  running back Max Wilson (34) during the fourth quarter against Charleston Southern Buccaneers at Memorial Stadium.  Mandatory Credit: Ashley Tumlin-Imagn Images
IMAGN IMAGES via Reuters Connect

Clemson vs Florida State Prediction 10/31/2026 Today’s College Football Picks

Pick details

Clemson vs Florida State Odds and Matchup Info
MATCHUP Clemson Tigers Florida State Seminoles
Team Records 4-3 3-4
Spread +6 -115 -6 -105
Moneyline +180 -218
Total Over 49.5 (-115) Under 49.5 (-105)
Where Doak Campbell Stadium, Tallahassee, FL
When Saturday, October 31, 2026
Time 07:00 PM EDT
TV ACC Network

The Clemson Tigers and the Florida State Seminoles meet in week 9 college football action from Doak Campbell Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. 

Clemson Tigers vs. Florida State Seminoles Prediction

I’m on Florida State in this one. I just truly don’t think this Clemson team is anywhere near as talented as recent Clemson teams and this could be the worst team that Dabo Swinney has had since taking over the Clemson job all those years ago. Florida State isn’t much better if we’re being 100% honest here, but I think they’re still good enough to win this game at home by at least a touchdown and add to Clemson’s misery while turning up the heat on Dabo’s seat. Give me FSU here.

Clemson Tigers Recap

The Clemson Tigers come into this game looking to bounce back after a 20-16 loss at the hands of the Virginia Tech Hokies last time out to sit at 4-3 this season. After this game, Clemson will head on the road for a matchup against the Syracuse Orange.

Tigers Alternate Wins & Losses In Last 4 Games

Tait Reynolds has thrown for 1,096 yards, 1 touchdown and 3 interceptions on 66.7% passing while Gideon Davidson leads Clemson in rushing with 492 yards and 5 touchdowns. Tait Reynolds sits behind Davidson on the ground with 164 yards and a touchdown. Bryant Wesco Jr. leads the Tigers in receiving with 378 yards and 34 catches, while T.J. Moore trails with 269 yards and 30 catches along with a touchdown. On defense, Corey Myrick has a team-high 53 tackles while Clemson’s defense as a whole has combined for 20 sacks and 4 interceptions.

Why the Clemson Tigers will win

  • Clemson has won each of its last six October games against Florida State.
  • Florida State has lost eight of its last nine games in October.
  • The road team has covered the spread in each of Clemson’s last four games.
  • Florida State has failed to cover the spread in each of its last four games as a favorite.
  • Clemson has won the first quarter in each of its last three games against Florida State.
  • Clemson has won the first half in each of its last nine games against Florida State.

Florida State Seminoles Recap

The Florida State Seminoles come into this game looking to bounce back from their 43-35 loss at the hands of the Miami Hurricanes last time out to sit at 3-4 this season. After this game, Florida State will head on the road for a matchup against the Boston College Eagles.

Seminoles Lose Two In A Row

Ashton Daniels has thrown for 1,618 yards, 12 touchdowns and 8 interceptions on 58.6% passing while Ousmane Kromah leads Florida State in rushing with 609 yards and 5 touchdowns. Ashton Daniels sits behind Kromah on the ground with 354 yards and 11 touchdowns. Duce Robinson leads the Seminoles in receiving with 407 yards and 22 catches along with 4 touchdowns, while Jayvan Boggs trails with 351 yards and 19 catches along with a touchdown. On defense, Chris Jones has a team-high 46 tackles while Florida State’s defense as a whole has combined for 18 sacks and 8 interceptions.

Why the Florida State Seminoles will win

  • The home team has won 12 of Florida State’s last 13 games.
  • Clemson has lost three of its last four games in October.
  • Clemson has failed to cover the spread in each of its last four games in Florida.
  • The favorite has covered the spread in six of the last eight games between Clemson and Florida State.
  • Florida State has won the first half in each of its last nine games as a home favorite.
  • Florida State has won the first quarter in three of its last four games against non-AP-ranked teams.

Chris Ruffolo's Pick: Florida State -6

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