Wake Forest vs Virginia Tech Prediction 2/21/2026 Today’s College Basketball Picks

The Wake Forest Demon Deacons and the Virginia Tech Hokies meet Saturday in college basketball action from the Cassell Coliseum. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Wake Forest Demon Deacons vs. Virginia Tech Hokies prediction.

Wake Forest Demon Deacons Recap

The Wake Forest Demon Deacons come into this game looking to add on to their 85-77 win over Clemson last time out to sit at 14-12 this season. After this game, Wake Forest will head on the road for a game against Boston College.

Demon Deacons Win 3 In A Row

Juke Harris leads the Demon Deacons in scoring and rebounding with 21.3 PPG and 6.7 RPG while Tre’Von Spillers has 11 PPG with 5.5 RPG and Myles Colvin has 12 PPG with 4.4 RPG. Nate Calmese has 10.4 PPG with a team-high 4.9 APG to lead the Demon Deacons in assists and to cap off the group of double-digit scorers for Wake Forest so far this season. Mekhi Mason has 7.3 PPG with 2.8 RPG as well this season. As a team, Wake Forest is averaging 79.7 PPG on 45.1% shooting from the field, 34% from three and 76.6% from the foul line this season.

Virginia Tech Hokies Recap

The Virginia Tech Hokies come into this game looking to shake off a 67-66 loss at the hands of Miami last time out. After this game, Virginia Tech will head on the road for a game against North Carolina.

Hokies Drop 4 Of Last 5

Amani Hansberry leads Virginia Tech in scoring and rebounding with 16.3 PPG and 8.4 RPG along with 3.3 APG while Neoklis Avdalas has 14.6 PPG with 3.5 RPG and a team-high 5 APG to lead the Hokies in assists up to this point in the year. Tobi Lawal has 12.8 PPG and Jaden Schutt has 10.6 PPG while Ben Hammond’s added 10.1 PPG with 3.5 APG to cap off the group of double-digit scorers for Virginia Tech up to this point in the year. Tyler Johnson has 9.5 PPG with 5.3 RPG and Jailen Bedford has 8.3 PPG with 2.8 RPG as well this season. As a team, Virginia Tech is averaging 83.1 PPG on 47% shooting from the field, 35.9% from the foul line and 70.3% from the foul line this season.

Wake Forest Demon Deacons @ Virginia Tech Hokies Betting Trends: February 21, 2026

Why the Virginia Tech Hokies will win

• Virginia Tech has won 13 of its last 14 games at Cassell Coliseum when playing with a rest advantage.
• Wake Forest has lost each of its last three games when playing with a rest disadvantage.
• Wake Forest has lost the first half in each of its last four day games.

Why the Wake Forest Demon Deacons will win

• Wake Forest has won each of its last five day games against Virginia Tech.
• Virginia Tech has lost each of its last four day games.
• Wake Forest has won the first half in each of its last four games against Virginia Tech.

Total Points Facts

• Each of Virginia Tech’s last six day games against non-AP-ranked opponents have produced a total of 153+ points.
• Eight of Wake Forest’s last 10 day games have produced a total of 159+ points.

Matchup/League Facts

• Virginia Tech ranks T34th among Division 1 teams for opponent steals per game this season (5.4).
• Virginia Tech ranks 38th among Division 1 teams for opponent three-point percentage this season (30.7%).
• Wake Forest ranks 36th among Division 1 teams for free throw percentage this season (76.7%).
• Wake Forest ranks T37th among Division 1 teams for steals per game this season (8.6).

Wake Forest Demon Deacons vs. Virginia Tech Hokies Prediction

I’m on Wake Forest and the points in this one. I get the case to be made for the Hokies, but I much prefer backing Virginia Tech on the road. This feels like a one possession game for me here so I’ll take Wake and the points in this one.

Chris Ruffolo's Pick: Wake Forest +4.5