Syracuse vs Louisville Prediction 3/3/2026 Today’s College Basketball Picks

In this article, we will formulate a Syracuse vs Louisville Prediction for this college basketball game on Tuesday, March 3rd. Let’s take a look at the prediction for this college basketball matchup.

Louisville Cardinals Preview

The Louisville Cardinals have a 20-9 overall record and a 9-7 record in the ACC. They are coming off an 80-75 road loss against Clemson and their previous three games were a 77-74 road loss against North Carolina, an 87-70 home win against Georgia Tech and a 95-85 road loss against SMU.

Offensively, Louisville averages 86 points per game, while allowing 72.2 points per game defensively. The Cardinals shoot with 47% from the field and grab 39.4 rebounds per game, while dishing out 17.3 assists per game. They average 3.3 blocks per game and 7.1 steals per game defensively.

Ryan Conwell leads Louisville in scoring, with an average of 18.4 points per game, while shooting with 40.5% from the field and 84.2% from the free throw line. Sananda Fru is the team’s leading rebounder with 6.4 per game. Aly Khalifa leads the team in assists with 2.7 per game.

Syracuse Orange Preview

The Syracuse Orange have a 15-14 overall record and a 6-10 record in the ACC. They are coming off an 88-83 road loss against Wake Forest and their previous three games were a 77-64 home loss against North Carolina, a 101-64 road loss against Duke and a 79-78 home win against SMU.

Offensively, Syracuse averages 75.9 points per game, while allowing 73.9 points per game defensively. The Orange shoot with 47% from the field and grab 34.2 rebounds per game, while dishing out 13 assists per game. They average 6 blocks per game and 6.4 steals per game defensively.

J.J. Starling leads Syracuse in scoring, with an average of 12 points per game, while shooting with 43.8% from the field and 54.8% from the free throw line. William Kyle III is the team’s leading rebounder with 7.3 per game. Naithan George leads the team in assists with 5.4 per game.

Syracuse Orange @ Louisville Cardinals Betting Trends: March 3, 2026

Why the Louisville Cardinals will win

• Louisville has won each of its last 27 games at KFC Yum! Center against non-AP-ranked opponents.
• Syracuse has lost each of its last six road games.
• Louisville has won the first half in each of its last 11 night games at KFC Yum! Center against non-AP-ranked opponents.

Why the Syracuse Orange will win

• Syracuse has won four of its last five games against Louisville.
• Louisville has lost three of its last four games.
• Syracuse has won the first half in 15 of its last 18 night games against non-AP-ranked opponents.

Total Points Facts

• Fourteen of Louisville’s last 15 night games against Conference opponents at KFC Yum! Center have produced a total of 158 or fewer points.
• Each of Syracuse’s last four night games have produced a total of 164+ points.

Syracuse vs Louisville Prediction

In this Syracuse vs Louisville Prediction, Louisville is coming as -15.5 home favorites. Louisville has been the better team this season but has been struggling lately with a 1-3 record in its last 4 games and has failed to cover the spread in its last 4 games. Syracuse has lost and failed to cover its last three games and have been terrible on the road, while having an inferior offense, scoring 10.1 points per game less than the hosts. I like Louisville to take care of business and cover the spread at home in this one.

Nikos Lagouretos's Pick: Louisville -15.5