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South Carolina vs Missouri Prediction 2/25/25 College Basketball Picks

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Missouri (20-7) vs South Carolina (11-16)

February 25, 2025 at 09:00 PM EST

The Line: Betting Odds: Missouri -13.5 — Over/Under: 146.5

(Get latest betting odds)

The South Carolina Gamecocks and the Missouri Tigers meet Tuesday in college basketball action from the Mizzou Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a South Carolina vs. Missouri prediction.

Matchup History

These two teams have not met yet this season, but the Gamecocks did win the last meeting by a final score of 72-64 back on January 27th, 2024, making it back-to-back wins for South Carolina in this head-to-head matchup.

South Carolina Recap

The South Carolina Gamecocks come into this game looking to add on to their 84-69 win over Texas last time out to improve to 11-16 on the year with their first conference win of the season. After this game, South Carolina will head home for a matchup with Arkansas.

Gamecocks Looking To Build On First Conference Win

Collin Murray-Boyles leads the Gamecocks in scoring and rebounding with 15.7 PPG and 8.5 RPG while Jamarii Thomas has 13.3 PPG with a team-high 3.2 APG to lead South Carolina in the assist department as the only pair of double-digit scorers for South Carolina up to this point in the year. Nick Pringle has 9.3 PPG with 6.2 RPG while Zachary Davis has 8.8 PPG with 4.3 RPG and Jacobi Wright has 8.3 PPG with 2.2 APG as well this season. As a team, South Carolina is averaging 70.1 PPG on 43.2% shooting from the field, 32.4% from three and 70.2% from the foul line this season.

Why the South Carolina Gamecocks will win

  • Missouri has lost 17 of its last 21 night games against the Southeastern Conference.
  • South Carolina has won three of its last four games against Missouri.

Missouri Recap

The Missouri Tigers come into this game looking to bounce back from a 92-85 loss at the hands of Arkansas last time out to sit at 20-7 on the year. After this game, Missouri will head on the road for a game against Vanderbilt.

Tigers Looking To Rebound After Three-Game Win Streak Snapped

Mark Mitchell leads the Tigers in scoring with 13.7 PPG along with 4.7 RPG while Caleb Grill has 13.4 PPG with 3.6 RPG and Tamar Bates has 13.3 PPG with 2.8 RPG to cap off the trio of double-digit scorers for Missouri so far this season. Anthony Robinson II has 9.3 PPG with 3.4 RPG and a team-high 3.3 APG to lead the Tigers in the assist department while Tony Perkins has 8.4 PPG with 2.5 APG and Trent Pierce has 7.3 PPG with 3.5 RPG as well so far this season. Josh Gray also has a team-high 5.1 RPG to lead Missouri on the glass up to this point in the year. As a team, Missouri is averaging 83.7 PPG on 48.3% shooting from the field, 36.9% from three and 72% from the foul line this season.

Why the Missouri Tigers will win

  • Missouri has won each of its last 14 games at Mizzou Arena against non-AP-ranked opponents.
  • South Carolina has lost each of its last nine games against AP-ranked opponents.

Total Points Facts

  • Five of Missouri’s last six night games at Mizzou Arena have produced a total of 147+ points.
  • Four of South Carolina’s last five night games against the Southeastern Conference have produced a total of 148+ points.

South Carolina vs. Missouri Prediction

I’m on Missouri here. It’s all well and good that South Carolina got their first conference win last time out, but it was overdue and it was also at home where they’ve played their better basketball so far this season. On the road, South Carolina has been dreadful for much of the season and I don’t expect it to get better here against a Missouri team that keeps defying logic and expectation so far this season. The Tigers just continue to be a wrecking ball and South Carolina can’t get out of their own way on the road. Give me Missouri in this one.

Chris Ruffolo's Pick: Missouri -13.5

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