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SMU vs Clemson Prediction 3/13/25 College Basketball Picks

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Clemson (26-5) vs SMU (22-9)

March 13, 2025 at 09:30 PM EDT

The Line: Betting Odds: Clemson -6.5 — Over/Under: 144.5

(Get latest betting odds)

The SMU Mustangs and Clemson Tigers meet Thursday in the college basketball ACC Quarterfinal at the Spectrum Center. Here’s an SMU vs Clemson Prediction. This article will include an SMU vs Clemson Pick.

SMU Mustangs Betting Preview 

The SMU Mustangs recently played Syracuse, Stanford, and Florida State. SMU looks for two straight wins for the first time since February 5-11. 

The SMU Mustangs are averaging 81.1 points on 48.2 percent shooting and allowing 72.2 points on 41.3 percent shooting. Boopie Miller is averaging 13.4 points and 3 rebounds, while Chuck Harris is averaging 12.9 points and 2.5 assists. Matt Cross is the third double-digit scorer and Kario Oquendo is grabbing 3.2 rebounds. The SMU Mustangs are shooting 38 percent from beyond the arc and 72.1 percent from the free throw line. The SMU Mustangs are allowing 33.4 percent shooting from deep and are grabbing 34.7 rebounds per game.

Clemson Tigers Betting Preview 

The Clemson Tigers recently beat Virginia, Boston College, and Virginia Tech. Clemson has won eight straight games and has one loss since January 11. 

The Clemson Tigers are averaging 77.1 points on 47 percent shooting and allowing 65.7 points on 42.8 percent shooting. Chase Hunter is averaging 16 points and 2.6 assists, while Ian Schieffelin is averaging 12.9 points and 9.3 rebounds. Viktor Lakhin is the third double-digit scorer and Jaeden Zackery is grabbing 3.2 rebounds. The Clemson Tigers are shooting 37.8 percent from beyond the arc and 76.5 percent from the free throw line. The Clemson Tigers are allowing 32.8 percent shooting from deep and are grabbing 32.5 rebounds per game.

SMU vs Clemson Injury Report

SMU will continue to be without Mitchell Holmes. Clemson will be without Ace Buckner, while Asa Thomas is questionable with an illness.

SMU vs Clemson Prediction

SMU didn’t have to kill itself yesterday to beat Syracuse so the legs should be fresh and ready to compete here. The problem is Clemson has been too good to bet against over these last two months. Clemson has lost just one game over that span and is a profitable 20-11 ATS on the season. We know the defense is there with Clemson every year, but this year’s squad has an offense that’s top-100 in scoring, top-70 in field goal percentage, and top-30 in three-point percentage. I’m just not eager to step in front of Clemson with the way it’s playing, especially with the rest advantage. The line is reasonable and Clemson did beat SMU by 10 points on the road about three weeks ago. I’ll lay the points with the Tigers.

Randy Chambers's Pick: Clemson -6.5

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