Stanford vs Louisville Prediction 3/13/25 College Basketball Picks
Louisville (25-6) vs Stanford (20-12)
Game Info: Thursday, March 13, 2025 at 7:00 pm (Spectrum Center)
Betting Odds: Louisville -10.5 -- Over/Under: 144.5 Click Here for the Latest Odds
Where to Watch: ESPN2
The Stanford Cardinal and the Louisville Cardinals meet Thursday in college basketball action from the Spectrum Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Stanford vs. Louisville prediction.
Matchup History
The Louisville Cardinals won the lone meeting this season at home back on March 8th, 2025, by a final score of 68-48.
Stanford Recap
The Stanford Cardinal come into this game fresh off of a 78-73 win over the Cal Golden Bears last time out to punch their ticket to the quarterfinals of the ACC tournament.
Cardinal Looking To Get Revenge In Conference Tournament
Maxime Reynaud leads the Cardinal in scoring and rebounding, averaging a double-double per game with 20.2 PPG and 10.8 RPG while Jaylen Blakes has 13.2 PPG with 3 RPG and a team-high 4.7 APG to lead the Cardinal in the assist department. Oziyah Sellers has 13.3 PPG to cap off the trio of double-digit scorers for Stanford up to this point in the year. Ryan Agarwal’s also added 7.4 PPG with 4.9 RPG and 2.1 APG as well on the year. As a team, Stanford is averaging 73 PPG on 43.3% shooting from the field, 33.8% from three and 78.7% from the foul line this season.
Why the Stanford Cardinal will win
- Louisville has lost six of its last seven games against non-AP-ranked opponents at a neutral venue.
- Stanford has won three of its last four night games.
Louisville Recap
The Louisville Cardinals come into the conference tournament as the 2-seed, finishing the year with an overall record of 25-6, including an 18-2 mark in ACC conference play.
Cardinals Looking To Sweep Series With Stanford
Chucky Hepburn leads the Cardinals in scoring and assists with 16.3 PPG and 5.9 APG along with 3.5 RPG and 2.4 SPG while Reyne Smith has 13.4 PPG with 2.8 RPG this season. Terrence Edwards Jr. has 15.8 PPG with 4 RPG and 2.6 APG and J’Vonne Hadley also has 12.4 PPG with a team-high 7.4 RPG to lead the Cardinals on the glass, also rounding out the group of double-digit scorers for Louisville so far this season. James Scott has also chipped in 7.1 PPG with 6.4 RPG as well on the year. As a team, Louisville is averaging 79.3 PPG on 45.6% shooting from the field, 33.3% from three and 74.9% from the foul line this season.
Why the Louisville Cardinals will win
- Louisville has won each of its last 12 night games against non-AP-ranked opponents.
- Stanford has lost each of its last 10 night games against AP-ranked opponents.
Total Points Facts
- Six of Louisville's last seven night games against non-AP-ranked opponents at a neutral venue have produced a total of 133 or fewer points.
- Five of Stanford's last six games against Conference opponents have produced a total of 141 or fewer points.
Stanford vs. Louisville Prediction
I’m on Louisville here. I get the allure of taking points with a team like Stanford in a quick revenge spot and the Cardinal have already had a chance to shake off the rust with a game and a win under their belt. However, Stanford’s also struggled against the top-tier ACC teams this season like Clemson, Duke and Louisville and in the conference tournament, I don’t see that changing here. I think Pat Kelsey is motivated to take this Louisville program to the top right away after a couple of frustrating down years for the program before he arrived, and I think Louisville sends a statement early with a win and cover here.
Chris’s Pick Louisville -10.5
AUTHOR: Chris Ruffolo

Follow Chris Ruffolo on Twitter @ruffthepickdawg