Nicholls State vs Oklahoma State Prediction 11/22/2025 Today’s College Basketball Picks

The Nicholls State Colonels and the Oklahoma State Cowboys meet Saturday in college basketball action from Gallagher-Iba Arena. Here’s a Nicholls vs Oklahoma State prediction. We will look at this from a betting perspective and determine the best Nicholls vs Oklahoma State pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Nicholls Colonels Betting Preview

The Colonels were unenviably matched up against a great Kentucky team in their opener this season. Nicholls trailed 28-15 by the break and ended up falling in a 77-51 blowout loss. Jalin Rice led the team with 13 points and two boards in 14 minutes, and Jalik Dunkley added 10 points and four rebounds. In their second outing of the year the Colonels played Eastern Illinois. Nicholls State scored 41 points in the second half but still lost 65-57. Jaylen Searles was the team leader in the losing effort with 20 points, six rebounds and three assists. Trae English was the only other Colonel in double-figures with 17 points and two boards. Sincere Malone added 10 rebounds with six points in 32 minutes. Game three versus Valparaiso was antlers loss for Nicholls, this time 68-63. Trae English led the way with 14 points and four rebounds in the losing effort, and two other players had 11 points apiece.

As for game four, the Colonels continued their season-opening losing streak versus Murray State last weekend. Nicholls was down 48-39 by the break and didn’t get any closer after coughing up another 51 points in the second on the way to a 99-79 result. Jalik Dunkley was the team leader with 18 points and four rebounds. Sincere Malone added 15 points with four assists and three rebounds in 36 minutes of work in the defeat.

Oklahoma State Cowboys Betting Preview

Over on the Oklahoma State side, they’ve got five games in the bag so far—and five victories. The first came 95-71 versus Oral Roberts on November 4. The Cowboys’ Vyctorius Miller topped the team with his 21 points and three rebounds. In game two versus Texas A&M, Oklahoma State bagged another win 87-63. Christian Coleman led the way this time on 16 points and three boards. As for game three, Oklahoma State took a win 94-67 versus Prairie View A&M. The Cowboys’ Miller was the leading scorer on 30 points with three boards and two assists. Game four was another victory, this time over Texas A&M-CC 85-69. Oklahoma State got 15 points and two rebounds in just 16 minutes from Anthony Roy.

Back on Wednesday versus South Florida, Oklahoma State got another win but this one was pretty close. The Cowboys trailed 45-44 at the break but got it going after halftime on a 59-50 run and took the comeback victory 103-95 in the end. Vyctorius Miller was tops on 24 points and five boards, while Kanye Clary doubled up on 12 points, 11 assists and seven boards.

Nicholls State Colonels @ Oklahoma State Cowboys Betting Trends: November 22, 2025

Why the Oklahoma State Cowboys will win

• Oklahoma State has won 20 of its last 21 day games at Gallagher-Iba Arena against non-AP-ranked opponents.
• Nicholls State has lost each of its last four games against non-Conference opponents.
• Nicholls State has lost the first half in each of its last five day games against non-Conference opponents.

Nicholls vs Oklahoma State Prediction

I’ll just stick with the Cowboys. I’m probably not going near this one, though. Oklahoma State wasn’t exactly dominant versus South Florida in their most recent outing, but did enough to get the eventual win. The Cowboys ended up shooting a stellar 59.4 percent from the field and had a 44-30 advantage in the paint alongside 19 team assists. That said, OK State also coughed up 18 turnovers and missed 10 of their 26 free throw attempts (61.5 percent). The good news is that this one (in all likelihood) will be another win; the only question is the margin of victory.

Andrew Jett's Pick: Oklahoma State Cowboys TBA