Nov 6, 2025; Ames, Iowa, USA; Grambling State Tigers forward Richard Amaefule (10) defends the shot from Iowa State Cyclones guard Jamarion Batemon (1) during the second half at James H. Hilton Coliseum. Mandatory Credit: Reese Strickland-Imagn Images
Reese Strickland-Imagn Images

Mississippi State vs Iowa State Prediction 11/10/2025 Today’s College Basketball Picks

Pick details

MATCHUP Bulldogs Mississippi State Cyclones Iowa State
Team Records 1-0 2-0
Spread +5.5 -115 -5.5 -105
Moneyline +180 -218
Total Over 150.5 (-112) Under 150.5 (-108)
Where Sanford Pentagon, Sioux Falls, SD
When Monday, November 10, 2025
Time 08:00 PM EST
TV ESPNU

In this article, we will formulate a Mississippi State vs Iowa State Prediction for this College Basketball game on Monday, November 10th. Let’s take a look at the prediction for this College Basketball matchup.

Iowa State Cyclones Preview

Iowa State has a 2-0 record this season. They are 2-0 ATS, 2-0 in Over/Under and have a 2-0 home record and a 0-0 away record. Iowa State is coming off a 102-62 home win against Grambling and will face Stonehill, St. John’s (NY) and Creighton next.

Offensively, Iowa State averages 95 points per game, which ranks 68th in the nation, while defensively, they allow 56 points per game (42nd). The Cyclones shoot with 53.4% from the field (51st), and with 41.4% from beyond the arc (55th). They shoot with 63.2% from the free throw line (282nd), and grab 42 rebounds per game (124th), while dishing out 19 assists per game (81st) and committing 10.5 turnovers per game (93rd).

Milan Momcilovic leads Iowa State in scoring, with an average of 20 points, 4 rebounds and 2.5 assists. Joshua Jefferson follows with 17 points, 9 rebounds and 3 assists per game, while Tamin Lipsey adds 14 points, 5 rebounds and 5.5 assists per game.

Mississippi State Bulldogs Preview

The Mississippi State Bulldogs have a 1-0 record this season and are coming off an 86-62 win at home against North Alabama. The Bulldogs shot 43.7% from the field and 29.6% from beyond the arc, while the Lions shot with 36.9% from the field and 36.8% from downtown. They made 66.7% of their free throws and grabbed 53 rebounds, while dishing out 15 assists and committing 7 turnovers. They had 17 fast break points and 42 points in the paint.

Achor Achor, Quincy Ballard, Jayden Epps, Shawn Jones Jr. and Josh Hubbard were the starting five for Mississippi State, with Hubbard being the top scorer with 27 points while shooting 43.8% from the field. Quincy Ballard followed with 8 points and 7 rebounds, while shooting 80% from the field. Shawn Jones Jr. added 7 points and 9 rebounds.

Mississippi State Bulldogs @ Iowa State Cyclones Betting Trends: November 10, 2025


Why the Iowa State Cyclones will win

  • Iowa State has won each of its last 10 Monday night games against non-Conference opponents.
  • Mississippi State has lost 10 of its last 11 games against AP-ranked opponents at a neutral venue.
  • Iowa State has won the first half in each of its last 11 Monday games against non-Conference opponents.

Why the Mississippi State Bulldogs will win

  • Mississippi State has won each of its last eight games when playing with a rest advantage.
  • Iowa State has lost each of its last four games against the Southeastern Conference.
  • Mississippi State has won the first half in each of its last four night games against non-Conference opponents.

Total Points Facts

  • Sixteen of Iowa State’s last 17 night games at a neutral venue have produced a total of 147 or fewer points.
  • Eighteen of Mississippi State’s last 21 games against non-Conference opponents at neutral venues have produced a total of 147 or fewer points.

Mississippi State vs Iowa State Prediction

In this Mississippi State vs Iowa State Prediction, Iowa State is coming as -5.5 home favorites. Both teams have been perfect this season, with Iowa State coming off a huge 40-point home victory and are playing their third straight game at home. Mississippi State is coming off a big 24-point home victory in their season opener and this will be their first road game of the season. Iowa State is looking terrific so far this season, as they are top-70 in the country both offensively and defensively, winning by an average of 39 points and they will take care of business in this one as well. Take Iowa State and lay the points at home.

Nikos Lagouretos's Pick: Iowa State -5.5

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