DePaul vs St. John’s Prediction 12/16/2025 Today’s College Basketball Picks

The DePaul Blue Demons and St. John’s Red Storm meet Tuesday in the college basketball action at the Carnesecca Arena. Here’s a DePaul vs St. John’s Prediction. This article will include a DePaul vs St. John’s Pick.

DePaul Blue Demons Betting Preview

The DePaul Blue Demons beat Morgan State and Wichita State, and they play UConn next. DePaul has won 3 straight games.

The DePaul Blue Demons are averaging 85.1 points on 46 percent shooting and allowing 74.7 points on 42.1 percent shooting. CJ Gunn is averaging 14.2 points and 3.5 rebounds, while Layden Blocker is averaging 11.5 points and 2.4 rebounds. NJ Benson is the third double-digit scorer and Kruz McClure is grabbing 1.9 rebounds. The DePaul Blue Demons are shooting 34.5 percent from beyond the arc and 70.9 percent from the free throw line. The DePaul Blue Demons are allowing 32.3 percent shooting from deep and are grabbing 34.1 rebounds per game.

St. John’s Red Storm Betting Preview

The St. John’s Red Storm beat Ole Miss and Iona, and they play Kentucky next. St. John’s has won 5 of its last 7 games.

The St. John’s Red Storm are averaging 89 points on 48.1 percent shooting and allowing 73 points on 40.8 percent shooting. Bryce Hopkins is averaging 14.9 points and 5 rebounds, while Zuby Ejiofor is averaging 14.4 points and 2.8 assists. Oziyah Sellers is the third double-digit scorer and Ian Jackson is dishing 1.2 assists. The St. John’s Red Storm are shooting 33.7 percent from beyond the arc and 72.3 percent from the free throw line. The St. John’s Red Storm are allowing 30.7 percent shooting from deep and are grabbing 36.7 rebounds per game.

Why the St. John’s Red Storm will win

• St. John’s has won each of its last 17 games at Carnesecca Arena against non-AP-ranked opponents.
• DePaul has lost each of its last 15 night games against AP-ranked opponents.
• DePaul has lost the first half in seven of its last eight night games against the Big East Conference.

Why the DePaul Blue Demons will win

• DePaul has won four of its last five night games.

Total Points Facts

• Each of St. John’s’ last 12 night games against the Big East Conference have produced a total of 150 or fewer points.
• Four of DePaul’s last five games against AP-ranked opponents have produced a total of 149 or fewer points.

DePaul vs St. John’s Prediction

St. John’s is the more talented team and being at home doesn’t hurt, but the Jonnies are just 5-4 ATS and have failed to cover 3 straight games overall. St. John’s can go through offensive droughts at times, and it’s led to some closer than expected results. DePaul can score the ball and has quietly won 6 of its last 7 games, which includes a recent upset over Wichita State. DePaul has scoring depth and if those shots fall, the Red Storm could be in for a battle. It’s also a look ahead spot for St. John’s with Kentucky on deck. This line feels disrespectful toward DePaul. Give me the free buckets.

Randy Chambers's Pick: DePaul +19.5