Canisius vs Duquesne Prediction 12/22/2025 Today’s College Basketball Picks

The Canisius Golden Griffins and the Duquesne Dukes meet Monday in college basketball action from Palumbo Center in Pittsburgh. Here’s a Canisius vs Duquesne prediction. We will look at this from a betting perspective and determine the best Canisius vs Duquesne pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Canisius Golden Griffins Betting Preview

The Griffins opened the year with a 4-3 run over their first seven games. Those wins came versus Allegheny, Mercyhurst, Maryland Eastern Shore and Binghamton. Since then it’s been a rough 1-4 run with a lone win over Maine. The losses otherwise have come versus Buffalo, Saint Peter’s, Siena and Rhode Island. Over 12 games so far that gives the Griffins a 5-7 record this year.

In the Rhode Island game back on Tuesday, the Griffins entered the second half with a 27-22 edge. Canisius was outscored 40-18 the rest of the way however, and ended up falling 62-45 in the end. Bryan Ndjonga was tops on 11 points with eight rebounds and Anthony Benard added 10 points with four assists and three rebounds as the only other team-player to make double-digits.

Duquesne Dukes Betting Preview

Over on the Duquesne side, they beat Niagara, Sacred Heart and Queens U in their first trio of outings. It’s been a 3-5 run since then though, with wins over Loyola MD, Central State OH and Stony Brook. Duquesne has otherwise lost to Villanova, Northeastern, William & Mary, Boise State and Nevada in that time. That makes for a 6-5 record over 11 games this year.

In the Nevada matchup back on December 13, the Dukes entered the break with a seven-point deficit. Duquesne fought back on a 40-36 run from there but still lost 78-75 in the end. Leading the team in scoring was Tarence Guinyard with 21 points, five assists and three rebounds. Jimmie Williams added 14 points with four rebounds and Maximus Edwards had 13 points.

Canisius Golden Griffins @ Duquesne Dukes Betting Trends: December 22, 2025

Why the Duquesne Dukes will win

• Canisius has lost 20 of its last 21 road night games against non-Conference opponents.
• Duquesne has won six of its last seven home games.
• Duquesne has won the first half in each of its last five home games against the Metro Atlantic Athletic Conference.

Why the Canisius Golden Griffins will win

• Duquesne has lost four of its last five night games against non-Conference opponents.
• Canisius has won each of its last three night games following a road loss.

Canisius vs Duquesne Prediction

I’ll lean toward Duquesne, but there’s not a lot to get excited about here with both teams struggling right now. The Dukes didn’t shoot great (39 percent) in their loss to Nevada and had a 32-22 deficit on points in the paint. Duquesne did make 18 of 20 free throws however, and had the edge on the boards 33-29. The Dukes have scored 75 or more points in 10 of their 11 games so far this year, but they’re also giving up a lot of scoring on the other side to decent offenses.

As for Canisius, they hit just 31.9 percent from the field in their loss to Rhode Island along with 18 turnovers and a 37-27 deficit on the boards. The Golden Griffins have been below 58 points in each of their last five losses, so they’re really going to have to push the offense in this one.

Andrew Jett's Pick: Duquesne Dukes TBA