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Clemson vs Louisville Prediction 1/7/25 College Basketball Picks

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Louisville (10-5) vs Clemson (12-3)

January 7, 2025 at 07:00 PM EST

The Line: Betting Odds: Louisville -3.5 — Over/Under: 145.5

(Get latest betting odds)

The Clemson Tigers and Louisville Cardinals meet Tuesday in college basketball action at the KFC Yum! Center. Here’s a Clemson vs Louisville Prediction. This article will include a Clemson vs Louisville Pick.

Clemson Tigers Betting Preview

The Clemson Tigers beat Stanford and Cal, and they play Florida State, Georgia Tech, and Pitt next. The Clemson Tigers are averaging 78.5 points on 46.4 percent shooting and allowing 66.9 points on 43.2 percent shooting. Chase Hunter is averaging 17.3 points and 2.5 assists, while Ian Schieffelin is averaging 13.6 points and 10.8 rebounds. Viktor Lakhin is the third double-digit scorer and Jaeden Zackery is grabbing 2.6 rebounds. The Clemson Tigers are shooting 38 percent from beyond the arc and 78.2 percent from the free throw line. The Clemson Tigers are allowing 31.9 percent shooting from deep and are grabbing 33.1 rebounds per game.

Louisville Cardinals Betting Preview

The Louisville Cardinals beat North Carolina and Virginia, and they play Pitt, Syracuse, and Virginia next. The Louisville Cardinals are averaging 77.8 points on 43 percent shooting and allowing 71 points on 44.2 percent shooting. Chucky Hepburn is averaging 15.5 points and 3.3 rebounds, while Terrence Edwards Jr. is averaging 13.7 points and 3.9 rebounds. Reyne Smith is the third double-digit scorer and Kasean Pryor is grabbing 6.1 rebounds. The Louisville Cardinals are shooting 29.8 percent from beyond the arc and 72.3 percent from the free throw line. The Louisville Cardinals are allowing 34.3 percent shooting from deep and are grabbing 36.4 rebounds per game.

Why the Louisville Cardinals will win

  • Louisville has won each of its last six games at KFC Yum! Center against non-AP-ranked opponents.
  • Clemson has lost 13 of its last 14 Tuesday night road games against the Atlantic Coast Conference.
  • Clemson has lost the first half in each of its last three games at KFC Yum! Center.

Why the Clemson Tigers will win

  • Louisville has lost each of its last nine Tuesday games against Conference opponents.
  • Clemson has won seven of its last eight night games against non-AP-ranked opponents.
  • Louisville has lost the first half in 15 of its last 19 night games against Conference opponents.

Total Points Facts

  • Four of Clemson’s last five games have produced a total of 148+ points.
  • Four of Louisville’s last five home games have produced a total of 149+ points.

Matchup/League Facts

  • Clemson ranks 29th among Division 1 teams for opponent assists per game this season (10.2).
  • Clemson ranks 35th among Division 1 teams for a three-point percentage this season (38.0%).

Clemson vs Louisville Injury Report

The Clemson Tigers will be without Ace Buckner for likely the entire season. The Louisville Cardinals won’t have Kasean Pryor and Koren Johnson for the remainder of the season. 

Clemson vs Louisville Prediction

The Louisville Cardinals have kind of righted the ship with four straight wins, which includes road wins over Florida State and Virginia. Coming back home, Louisville is going to get the benefit of the doubt. However, that doesn’t mean Louisville is a good basketball team. Louisville still has shooting issues and has some bad losses. The Clemson Tigers have won eight of their last 10 games and are still tough defensively. Clemson took Memphis down to the wire, beat Kentucky, and beat up Penn State. Clemson doesn’t get blown out often and gives itself a chance every night with its gritty play. I like the points with Clemson when I can find them. Clemson puts up a fight and finds ways to hang around, even if it’s ugly. This should be a physical game.

Randy Chambers's Pick: Clemson +3.5

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