Wake Forest vs Duke Prediction 11/29/2025 Today’s College Football Picks

The Wake Forest Demon Deacons and the Duke Blue Devils meet in week 14 college football action from Wallace Wade Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Wake Forest Demon Deacons vs. Duke Blue Devils prediction.

Wake Forest Demon Deacons Recap

The Wake Forest Demon Deacons come into this game looking to add on to their 52-14 win over Delaware last time out to sit at 8-3 this season.

Demon Deacons Win 3 Straight

Robby Ashford has thrown for 1,827 yards, 7 touchdowns and 6 interceptions on 58.5% passing while also rushing for 460 yards and 6 TDs. Deshawn Purdie’s also thrown for 618 yards, 6 TDs and 3 INTs on 50% passing. Demond Claiborne has a team-high 849 rushing yards with 10 touchdowns while Chris Barnes leads Wake’s receiving group with 37 grabs for 523 yards his season while Carlos Hernandez has 28 catches for 445 yards and 3 TDs. Sterling Berkhalter has 366 receiving yards and 2 TDs and Micah Mays Jr. has 302 receiving yards with 2 scores while four more Demon Deacons have 100+ receiving yards as well this season. On defense, Nick Andersen has a team-high 89 total tackles while Langston Hardy has a team-high 6.5 sacks and Nuer Gatkuoth has 6 sacks. As a unit, Wake Forest’s defense has combined for 23 sacks and 4 interceptions so far this season.

Duke Blue Devils Recap

The Duke Blue Devils come into this game looking to add on to their 32-25 win over North Carolina last time out to improve to 6-5 this season.

Blue Devils Trying To Finish On High Note

Darian Mensah has thrown for 3,182 yards, 26 touchdowns and 4 interceptions on 67.4% passing while Nate Sheppard has a team-high 790 rushing yards with 7 TDs and Anderson Castle has 414 rushing yards with 9 touchdowns. Cooper Barkate leads Duke’s receiving group with 55 catches for 895 yards and 6 touchdowns while Que’Sean Brown has 614 receiving yards with 3 TDs. Sahmir Hagans has 403 receiving yards with 5 scores and Jeremiah Hasley has 358 receiving yards as well this season. On defense, Caleb Weaver has a team-high 73 total tackles while Vincent Anthony Jr. has 6.5 sacks and Josiah Green has 3.5 sacks. As a unit, Duke’s defense has combined for 23 sacks and 10 interceptions so far this season.

Wake Forest Demon Deacons @ Duke Blue Devils Betting Trends: Week 14

Why the Duke Blue Devils will win

• Duke has won each of its last 14 games against non-AP-ranked teams at Brooks Field at Wallace Wade Stadium.
• Wake Forest has lost each of its last 10 November games as an underdog against non-AP-ranked teams.
• Wake Forest has failed to cover the spread in five of its last six November games as an underdog against non-AP-ranked teams.
• Duke has covered the spread in 12 of its last 15 home games against conference opponents.

Why the Wake Forest Demon Deacons will win

• The underdog has won four of Duke’s last five games.
• Duke has lost three of its last four games as a favorite.
• Wake Forest has covered the spread in seven of its last eight games.
• Duke has failed to cover the spread in each of its last four games as a favorite.
• Wake Forest has won the first half in seven of its last eight games against conference opponents.

Total Points Facts

• Seven of Duke’s last eight games against non-AP-ranked teams have gone OVER the total points line.
• Each of Wake Forest’s last five November games as an underdog have gone UNDER the total points line.

Duke Blue Devils Player Prop Facts

• Heading into Week 14, Darian Mensah is one of only two players in the league to record two or more passing touchdowns in nine consecutive appearances this season.

Wake Forest Demon Deacons Player Prop Facts

• Nuer Gatkuoth has recorded at least one sack in four consecutive games – equal-longest streak in the FBS, heading into Week 14.

Matchup/League Facts

• Duke ranks 5th among FBS teams for 4th down conversion percentage this season (75.9).
• Duke ranks T130th among FBS teams for red zone percentage against this season (93.3).
• Wake Forest ranks 131st among FBS teams for Q4 points per game this season (3.3).
• Wake Forest ranks T10th among FBS teams for Q2 opponent points per game this season (4.5).

Wake Forest Demon Deacons vs. Duke Blue Devils Prediction

I’m on Wake Forest here. I know it’s senior day for Duke, but the thing is that the Blue Devils clinched their bowl game last week so there could be a bit of a hangover here after that. Wake Forest’s defense has been criminally underrated this season and I think Wake’s the better team catching a point here. Give me the Demon Deacons in this one.

Chris Ruffolo's Pick: Wake Forest +1.5