UTSA vs Charlotte Prediction 11/15/2025 Today’s College Football Picks

In this article we will formulate a UTSA vs Charlotte prediction for this College Football game on Saturday, November 15th at Jerry Richardson Stadium in Charlotte, North Carolina. Let’s take a look at the prediction for this week 12 matchup. 

UTSA Roadrunners Betting Preview

The UTSA Roadrunners are 4-5 (2-3) this year after they lost to South Florida by a score of 55-23 in their last game. UTSA trailed 45-10 at halftime, but did win the second half by a total of 13-10 in the blowout loss. The Roadrunners were out gained by a total of 471-381, went 7-18 on third downs, and lost the turnover battle by a total of 2-1 in the game. Owen McCown went 16-23 for 200 yards, one touchdown, and one interception, while Will Henderson III rushed five times for 27 yards. Houston Thomas led the receivers with seven catches for 77 yards in the loss. The UTSA defense recorded one sack and seven tackles for loss in the game. 

Prior to that game, UTSA defeated Tulane by a score of 48-26, but did lose to North Texas by a score of 55-17 before that. The Roadrunners have alternated wins and losses over their last six games and they are currently 10th in the American standings. UTSA has scored 32.8 points per game with 233.3 passing yards and 166.4 rushing yards per game, while they have allowed 33.0 points against per game this season. Owen McCown has thrown for 1,880 yards, 18 touchdowns, and five interceptions, while Robert Henry Jr has rushed 130 times for 982 yards and nine scores this year. 

Charlotte 49ers Betting Preview

The Charlotte 49ers are 1-8 (0-6) this season after they lost to East Carolina by a score of 48-22 in their last game. Charlotte trailed 35-14 at halftime and only managed eight points in the second half in the loss. The 49ers were out gained by a total of 407-324, went 4-14 on third downs, and lost the turnover battle by a total of 2-1 in the game. Grayson Loftis went 20-31 for 279 yards, three touchdowns, and one interception, while Cameren Smith rushed five times for 35 yards. Sean Brown led the receivers with seven catches for 119 yards and one touchdown in the loss. The Charlotte defense recorded three sacks and six tackles for loss in the game. 

Prior to that game, Charlotte lost to North Texas by a score of 54-20 and Temple by a score of 49-14. The 49ers have lost six games in a row and they are currently last in the American standings. Charlotte has scored 18.0 points per game with 225.4 passing yards and 99.3 rushing yards per game, while they have allowed 38.4 points against per game this season. Grayson Loftis has thrown for 1,045 yards, eight touchdowns, and five interceptions, while Javen Nicholas has 44 receptions for 631 yards and five scores this season. 

Why the UTSA Roadrunners will win

• UTSA has won each of its last nine November games as a favorite.
• Charlotte has lost each of its last six games against conference opponents.
• The road team has covered the spread in each of Charlotte’s last four games.
• Charlotte has failed to cover the spread in each of its last four games as a home underdog against teams from Texas.

Total Points Facts

• Thirteen of UTSA’s last 15 games against non-AP-ranked teams have gone OVER the total points line.
• Each of Charlotte’s last four home games have gone OVER the total points line.

Matchup/League Facts

• Charlotte ranks 135th among FBS teams for 1st downs against this season (227).
• Charlotte ranks 134th among FBS teams for points allowed per game this season (38.4).
• UTSA ranks 128th among FBS teams for red zone percentage against this season (93.9).
• UTSA ranks T123rd among FBS teams for points allowed per game this season (33.0).

UTSA vs Charlotte Prediction 

UTSA comes into this matchup after getting dominated by South Florida last week and they will look to bounce back, but they will be back on the road. The Roadrunners have been a very good home team this year, but it has been a different story on the road. Charlotte is still looking for their first win against a FBS team and they have allowed 48+ points in four of their last five games. I don’t truly trust UTSA on the road, but they should be fine against a team like Charlotte. Take UTSA to cover.

David Racey is 117-95 (55%) in College Football this season and is one of the top College Football Handicappers on the site. Click here for his premium plays for the week!

David Racey's Pick: UTSA -18.5