San Diego State vs Northern Illinois Prediction 9/27/2025 Today’s College Football Picks

The San Diego State Aztecs and the Northern Illinois Huskies meet in week 5 college football action from Huskie Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Diego State Aztecs vs. Northern Illinois Huskies prediction.

San Diego State Aztecs Recap

The San Diego State Aztecs come into this game looking to add on to their 34-0 win over Cal last time out to sit at 2-1 this season. After this game, San Diego State will head home for a game against Colorado State.

Aztecs Coming Off Of Huge Shutout Of Golden Bears

Jayden Denegal has thrown for 529 yards and 3 touchdowns on 58.9% passing while Lucky Sutton leads the Aztecs on the ground with 249 rushing yards and 3 touchdowns so far this season. Jordan Napier leads San Diego State in receiving with 19 grabs for 241 yards and a touchdown while Jacob Bostick also has 126 receiving yards on 10 catches with 2 touchdowns. On defense, Owen Chambliss has a team-high 23 total tackles including 16 solo tackles while August Salvati has a team-high 3.5 sacks so far this season.

Northern Illinois Huskies Recap

The Northern Illinois Huskies come into this one looking to rebound from their 38-10 loss at the hands of the Mississippi State Bulldogs last time out to sit at 1-2 this season. After this game, Northern Illinois will head home for a game against Miami-Ohio.

Huskies Drop Back-To-Back Outings

Josh Holst has thrown for 327 yards a touchdown and 2 interceptions on 63.5% passing while Chavon Wright leads the Huskies in rushing with 214 yards and a touchdown and Telly Johnson Jr. has 199 rushing yards with a touchdown as well this season. DeAree Rogers has a team-high 16 catches for 173 yards as well this season. On defense, Quinn Urwiler has a team-high 34 total tackles including 17 solo tackles while NIU’s defense as a whole has combined for 4 sacks and an interception so far this season.

San Diego State Aztecs @ Northern Illinois Huskies Betting Trends: Week 5

Why the Northern Illinois Huskies will win

• San Diego State has lost each of its last seven road games in September.
• The home team has won five of San Diego State’s last six games.
• The underdog has covered the spread in each of Northern Illinois’ last four games at Brigham Field at Huskie Stadium.
• San Diego State has failed to cover the spread in 16 of its last 20 September games as a favorite.
• San Diego State has lost the first half in four of its last five road games against non-conference opponents.

Why the San Diego State Aztecs will win

• Northern Illinois has lost each of its last eight September games against non-AP-ranked teams.
• The favorite has won each of Northern Illinois’ last eight games.
• Northern Illinois has failed to cover the spread in each of its last six home games.
• San Diego State has covered the spread in each of its last four games against opponents from the Mid-American Conference.
• Northern Illinois has lost the first half in each of its last four games against opponents from the Mountain West Conference.

Total Points Facts

• Each of Northern Illinois’ last eight games against opponents from the Mountain West Conference have gone OVER the total points line.
• Each of San Diego State’s last five road games have gone OVER the total points line.

Northern Illinois Huskies Player Prop Facts

• Heading into Week 5, Chavon Wright leads Northern Illinois for touchdowns (1) this season.

San Diego State Aztecs Player Prop Facts

• Heading into Week 5, Chris Johnson leads the Mountain West Conference for forced fumbles (1) this season.

Matchup/League Facts

• Northern Illinois ranks 135th among FBS teams for points per game this season (12.7).
• Northern Illinois ranks 135th among FBS teams for 1st downs this season (44).
• San Diego State ranks T1st among FBS teams for red zone percentage this season (100.0).
• San Diego State ranks 133rd among FBS teams for 1st downs this season (49).

San Diego State Aztecs vs. Northern Illinois Huskies Prediction

I’m on San Diego State here. I just don’t trust Northern Illinois offensively. Granted, boith of these teams have struggled mostly in their step up spots this season, but it’s also worth remembering that this is a Northern Illinois team that almost lost outright to Holy Cross to start the year. San Diego State has to really show something on the road, but I’ve been a lot more impressed with what I’ve seen from the Aztecs to this point and I think San Diego State gets the win and cover on the road here. Give me San Diego State.