Murray State vs Jacksonville State Prediction 9/20/2025 Today’s College Football Picks

The Murray State Racers and the Jacksonville State Gamecocks meet in week 4 college football action from AmFirst Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Murray State Racers vs. Jacksonville State Gamecocks prediction.

Murray State Racers Recap

The Murray State Racers come into this game looking to rebound from a 37-21 loss to Georgia State last time out. After this game, Murray State will head on the road for a series against South Dakota.

Racers Looking For Huge Upset For First Win

Jim Ogle has thrown for 618 yards, 3 touchdowns and 4 interceptions on 62.7% passing while Jawaun Northington has rushed for 156 yards and 3 touchdowns this season. Darius Cannon leads the Racers in receiving with 26 grabs for 198 yards while Lucas Desjardins and Cam Bulluck each have 100+ receiving yards as well this season. On defense, Dylan Rowsey has a team-high 45 total tackles including a team-high 35 solo tackles. As a unit, Murray State’s defense has combined for 3 sacks and 4 interceptions as well this season.

Jacksonville State Gamecocks Recap

The Jacksonville State Gamecocks come into this game looking to rebound from a 41-34 loss to Georgia Southern last time out to drop to 1-2 on the year. After this game, Jacksonville State will head on the road for a game against Southern Miss.

Gamecocks Looking To Get Back To .500

Gavin Wimsatt has thrown for 369 yards, a touchdown and 2 interceptions on 56.9% passing while also rushing for 166 yards and 3 touchdowns. Cam Cook has rushed for a team-high 390 yards and 2 touchdowns while Andrew Paul has 92 rushing yards and a pair of scores. Brock Rechsteiner leads the Gamecocks with 102 receiving yards while Caleb Coombs has a team-high 10 catches for 85 yards this season. On defense, Trevor Woods leads the Gamecocks with 21 total tackles including 13 solo tackles this season. As a unit, Jacksonville State has combined for 6 sacks and an interception so far this season.

Murray State Racers @ Jacksonville State Gamecocks Betting Trends: Week 4

Why the Jacksonville State Gamecocks will win

• Jacksonville State has won each of its last seven games at AmFirst Stadium.
• Jacksonville State has covered the spread in each of its last four home games in September.

Why the Murray State Racers will win

• Jacksonville State has lost six of its last seven games against non-conference opponents.

Total Points Facts

• Five of Jacksonville State’s last six games in September have gone OVER the total points line.

Jacksonville State Gamecocks Player Prop Facts

• Heading into Week 4, Cam Cook ranks 2nd amongst FBS players for rushing attempts (67) this season.

Matchup/League Facts

• Jacksonville State ranks T132nd among FBS teams for Q4 opponent points per game this season (12.7).
• Jacksonville State ranks T129th among FBS teams for average point differential in fourth quarters this season (-7.0).

Murray State Racers vs. Jacksonville State Gamecocks Prediction

I’m leaning towards JSU here. I don’t love the number but Murray State for me is still one of the more below-average teams in FCS, and I think scoring 21 points last week says more about the lack of defense for Georgia State than it does anything positive about Murray State coming into this game. I think the Gamecocks run up and down on Murray State here and get the win and cover at home so I’ll lay it with Jacksonville State if forced to pick.