Clemson Tigers defensive back Ronan Hanafin (5) and Clemson Tigers linebacker Wade Woodaz (17) go to tackle LSU Tigers wide receiver Aaron Anderson (1) Saturday, Aug. 30, 2025 during the NCAA football game at Memorial Stadium in Clemson, South Carolina. LSU Tigers won 17-10.

Louisiana Tech vs LSU Prediction 9/6/2025 Today’s College Football Picks

Pick details

Louisiana Tech (1-0) vs LSU (1-0)

September 6, 2025 at 07:30 PM EDT

The Line: Betting Odds: LSU -37.5 — Over/Under: +51.5

(Get latest betting odds)

The Louisiana Tech Bulldogs and LSU Tigers meet Saturday in college football action at Tiger Stadium. Here’s a Louisiana Tech vs LSU Prediction. This article will include a Louisiana Tech vs LSU Pick.

Louisiana Tech Bulldogs Betting Preview


The Louisiana Tech Bulldogs beat SE Louisiana, and they play New Mexico State and Southern Miss next. Louisiana Tech has split its last 10 games. Trey Kukuk is completing 73.7 percent of his passes for 130 yards, 1 touchdown, and 0 interceptions. Eli Finley and Dedrick Latulas have combined for 84 receiving yards on 5 catches, while Marques Singleton Jr. has 4 receptions.

The Louisiana Tech Bulldogs ground game is averaging 112.2 yards per contest, and Clay Thevenin leads the way with 61 yards and 1 touchdown. Defensively, Louisiana Tech is allowing 0 points and 271 yards per game. Kolbe Fields leads the Louisiana Tech Bulldogs with 13 tackles, Mekhi Mason has 2 sacks and Jakari Foster has 1 interception.

LSU Tigers Betting Preview


The LSU Tigers beat Clemson, and they play Florida and SE Louisiana next. LSU has won 4 straight games. Garrett Nussmeier is completing 73.7 percent of his passes for 232 yards, 1 touchdown, and 0 interceptions. Aaron Anderson and Ju’Juan Johnson have combined for 130 receiving yards on 11 catches, while Barion Brown has 5 receptions.

The LSU Tigers ground game is averaging 114 yards per contest, and Caden Durham leads the way with 74 yards and 1 touchdown. Defensively, LSU is allowing 10 points and 261 yards per game. West Weeks leads the LSU Tigers with 5 tackles, PJ Woodland has 1 sack and Mansoor Delane has 1 interception.

Louisiana Tech vs LSU Prediction

You can make a case for LSU in a beat down as there’s an obvious talent gap and the Tigers have covered 6 of their last 8 games when favorites of 20 or more points. However, this is the ultimate trap game, with LSU playing Clemson opening week and seeing Florida on deck.

Louisiana Tech will obviously be the more excited team. Also, this is the same Louisiana Tech team that hung around with Arkansas and NC State last year. Throw in a Nebraska game in 2023, and Louisiana Tech has covered 3 straight games when underdogs of 20 or more points. We’re getting a truckload of points, folks. Give me Louisiana Tech and the points.

Randy Chambers's Pick: LA Tech +37.5

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