Iowa State vs Oklahoma State Prediction 11/29/2025 Today’s College Football Picks

In this article we will formulate an Iowa State vs Oklahoma State prediction for this College Football game on Saturday, November 29th at Boone Pickens Stadium in Stillwater, Oklahoma. Let’s take a look at the prediction for this week 14 matchup. 

Iowa State Cyclones Betting Preview

The Iowa State Cyclones are 7-4 (4-4) this season after they defeated Kansas by a score of 38-14 in their last game. Iowa State led 17-0 at halftime, but their lead was cut to 24-14 in the third, before they pulled away for the 24-point win. The Cyclones out gained Kansas by a total of 462-323, went 9-16 on third downs, and won the turnover battle by a total of 1-0 in the game. Rocco Becht went 18-23 for 241 yards and three touchdowns, while Carson Hansen rushed 22 times for 120 yards and one score. Brett Eskildsen led the receivers with six catches for 73 yards and two touchdowns in the win. 

Prior to that game, Iowa State defeated TCU by a score of 20-17, but lost to Arizona State by a score of 24-19 before that. The Cyclones have won two games in a row and they are currently tied for eighth in the Big 12 standings. Iowa State has scored 28.1 points per game with 231.3 passing yards and 169.4 rushing yards per game, while they have allowed 20.8 points against per game this season. Rocco Becht has thrown for 2,471 yards, 15 touchdowns, and nine interceptions, while Carson Hansen has rushed for 841 yards and six scores on 163 carries this season. 

Oklahoma State Cowboys Betting Preview

The Oklahoma State Cowboys are 1-10 (0-8) this year after they lost to UCF by a score of 17-14 last week. Oklahoma State led 14-0 at halftime, but they were outscored 17-0 in the second half for the heartbreaking loss. The Cowboys were out gained by a total of 396-228, went 4-13 on third downs, and won the turnover battle by a total of 2-1 in the game. Zane Flores went 13-28 for 124 yards, one touchdown, and one interception, while Rodney Fields Jr rushed for 87 yards on 19 carries. Gavin Freeman led the receivers with five catches for 40 yards and one score in the loss. 

Prior to that game, Oklahoma State lost to Kansas State by a score of 14-6 and Kansas by a score of 38-21. The Cowboys have lost 10 games in a row and they are currently last in the Big 12 standings. Oklahoma State has scored 14.3 points per game with 171.5 passing yards and 126.6 rushing yards per game, while they have allowed 34.5 points against per game this season. Zane Flores has thrown for 1,288 yards, three touchdowns, and six interceptions, while Rodney Fields Jr has rushed 124 times for 614 yards and one score this year.

Why the Iowa State Cyclones will win

• Oklahoma State has lost each of its last 10 games.
• The favorite has won 16 of Oklahoma State’s last 17 games.
• Oklahoma State has failed to cover the spread in nine of its last 11 games at Boone Pickens Stadium.
• Iowa State has covered the spread in three of its last four games in November.

Total Points Facts

• Each of Iowa State’s last four games in November have gone UNDER the total points line.
• Five of Oklahoma State’s last six home games against conference opponents have gone OVER the total points line.

Matchup/League Facts

• Oklahoma State ranks 135th among FBS teams for 4th down conversion percentage against this season (80.0).
• Oklahoma State ranks 134th among FBS teams for points per game this season (14.3).
• Iowa State ranks T23rd among FBS teams for Q4 opponent points per game this season (4.4).
• Iowa State ranks 29th among FBS teams for time of possession per game this season (31:27).

Iowa State vs Oklahoma State Prediction 

Oklahoma State has played better in their last two games and they have been much more competitive, but they are still looking for their first FBS wins of the season. The Cowboys have scored 17 points or fewer in four of their last five games, and they have really struggled to move the football. Iowa State has won two games in a row and they dominated Kansas last time out. The Cyclones have shown some inconsistencies this year, but they should be fine against this Oklahoma State squad. Take Iowa State here.

David Racey is 140-118 (54%) in College Football this season and is one of the top College Football Handicappers on the site. Click here for his premium plays for the week!

David Racey's Pick: Iowa State -14