Akron Zips quarterback Ben Finley (10) stretches during warmups before the season opening game against Wyoming, Aug. 28, 2025, at InfoCision Stadium in Akron, Ohio.

Duquesne vs Akron Prediction 9/20/2025 Today’s College Football Picks

Pick details

Duquesne (1-2) vs Akron (0-3)

September 20, 2025 at 06:00 PM EDT

The Line: Betting Odds: Akron -7.5 — Over/Under: 51.5

(Get latest betting odds)

The Duquesne Dukes and the Akron Zips meet in week 4 college football action from InfoCision Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Duquesne Dukes vs. Akron Zips prediction.

Duquesne Dukes Recap

The Duquesne Dukes come into this game looking to bounce back from a 35-21 loss to Lehigh last time out to sit at 1-2 on the year. After this game, Duquesne will head home for a game against New Haven.

Dukes Looking For FBS Upset

Tyler Riddell has thrown for 604 yards, 8 touchdowns and an interception on 64.8% passing while Taj Butts leads the Dukes in rushing with 103 yards on the ground. Joey Isabella leads Duquesne with 22 catches for 319 yards and 3 touchdowns while B.J. Alexander and Daniel Tarabrella each have a pair of touchdown grabs so far this season. On defense, Jabari Odoemenem has a team-high 20 total tackles while Duquesne as a team have combined for 5 sacks and an interception so far this year.

Akron Zips Recap

The Akron Zips come into this one looking to bounce back after their loss to UAB last time out to sit at 0-3 on the year. After this game, the Zips will head on the road for a game against Toledo.

Zips Still Searching For First Win

Ben Finley has thrown for 475 yards, 2 touchdowns and an interception on 44.7% passing while Sean Patrick has rushed for 171 yards and a touchdown. Jordan Gant has rushed for 117 yards as well while Israel Polk leads Akron in receiving with 116 receiving yards and 2 touchdowns for Akron’s receiving group this season. On defense, Shammond Cooper has a team-high 25 total tackles while Markus Boswell has a pair of interceptions and Bruno Dall has 1.5 sacks so far this season. 

Duquesne Dukes @ Akron Zips Betting Trends: Week 4

Why the Akron Zips will win

  • Akron has won four of its last five home games against non-conference opponents.

Why the Duquesne Dukes will win

  • Akron has lost eight of its last nine games against non-conference opponents.
  • Akron has failed to cover the spread in nine of its last 10 home games against non-conference opponents.
  • Akron has lost the first half in eight of its last nine games against non-conference opponents.

Total Points Facts

  • Four of Akron’s last five home games have gone UNDER the total points line.

Akron Zips Player Prop Facts

  • Heading into Week 4, Israel Polk leads Akron for touchdowns (2) this season.

Matchup/League Facts

  • Akron ranks 136th among FBS teams for passing yards allowed per game this season (365.0).
  • Akron ranks T135th among FBS teams for Q2 points per game this season (1.0).

Duquesne Dukes vs. Akron Zips Prediction

I’m on Akron here. I think Duquesne is just a mess of an FCS team, and if there was a spot for Akron to get a rare win, it would be here. Akron showed some fight in that game against UAB and while it’s not something I’m going to roll with often, I’m still siding with Akron in this one.

Chris Ruffolo's Pick: Akron -7.5

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