Sep 13, 2025; Blacksburg, Virginia, USA;  Old Dominion Monarchs quarterback Colton Joseph (1) runs the ball as Virginia Tech Hokies cornerback Isaiah Brown-Murray (9) pursues during the third quarter at Lane Stadium. Mandatory Credit: Brian Bishop-Imagn Images

Coastal Carolina vs Old Dominion Prediction 10/4/2025 Today’s College Football Picks

Pick details

Coastal Carolina (2-2) vs Old Dominion (3-1)

October 4, 2025 at 06:00 PM EDT

The Line: Betting Odds: Old Dominion -18.5 — Over/Under: +54.5

(Get latest betting odds)

The Coastal Carolina Chanticleers and Old Dominion Monarchs meet Saturday in college football action at S.B. Ballard Stadium. Here’s a Coastal Carolina vs Old Dominion Prediction. This article will include a Coastal Carolina vs Old Dominion Pick.

Coastal Carolina Chanticleers Betting Preview


The Coastal Carolina Chanticleers lost to East Carolina, beat South Alabama, and they play UL Monroe next. Coastal Carolina has lost 8 of its last 12 games. Tad Hudson is completing 50 percent of his passes for 321 yards, 2 touchdowns, and 2 interceptions. Bryson Graves and Robby Washington have combined for 244 receiving yards and 1 touchdown, while Cameron Wright has 7 receptions.

The Coastal Carolina Chanticleers ground game is averaging 146.3 yards per contest, and Ja’Vin Simpkins leads the way with 193 yards and 2 touchdowns. Defensively, Coastal Carolina is allowing 28.5 points and 381 yards per game. Shane Bruce leads the Coastal Carolina Chanticleers with 27 tackles, Zeke Campbell has 2 sacks and Myles Woods has 1 interception.

Old Dominion Monarchs Betting Preview


The Old Dominion Monarchs beat Liberty and Virginia Tech, and they play Marshall next. Old Dominion has won 4 of its last 5 games. Colton Joseph is completing 68.1 percent of his passes for 900 yards, 5 touchdowns, and 4 interceptions. Ja’Cory Thomas and Tre’ Brown III have combined for 524 receiving yards and 4 touchdowns, while Na’eem Abdul-Rahim Gladding has 15 receptions.

The Old Dominion Monarchs ground game is averaging 238.3 yards per contest, and Colton Joseph leads the way with 367 yards and 4 touchdowns. Defensively, Old Dominion is allowing 16.5 points and 345.5 yards per game. Mario Easterly leads the Old Dominion Monarchs with 32 tackles, Jeremy Mack Jr. has 2 sacks and Jerome Carter has 2 interceptions.

Coastal Carolina Chanticleers @ Old Dominion Monarchs Betting Trends: Week 6


Why the Old Dominion Monarchs will win

  • Old Dominion has won five of its last six October games against non-AP-ranked teams.
  • Old Dominion has covered the spread in five of its last six October games against non-AP-ranked teams.
  • Coastal Carolina has failed to cover the spread in four of its last five games.
  • Old Dominion has won the first half in three of its last four home games against conference opponents.

Why the Coastal Carolina Chanticleers will win

  • Coastal Carolina has won five of its last seven October games as an underdog.
  • Old Dominion has lost three of its last four games against conference opponents.
  • Coastal Carolina has covered the spread in six of its last seven October games as a road underdog.
  • Old Dominion has failed to cover the spread in 10 of its last 12 games as a favorite against non-AP-ranked teams.

Total Points Facts


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  • Each of Coastal Carolina’s last eight October road games against non-AP-ranked teams have gone UNDER the total points line.
  • Five of Old Dominion’s last six games in Virginia have gone OVER the total points line.

Old Dominion Monarchs Player Prop Facts

  • Ja’Cory Thomas has recorded 75+ receiving yards in three consecutive games – equal-longest streak in the FBS, heading into Week 6.

Coastal Carolina Chanticleers Player Prop Facts

  • Heading into Week 6, Ja’Vin Simpkins leads Coastal Carolina for touchdowns (2) this season.

Matchup/League Facts

  • Old Dominion ranks 8th among FBS teams for red zone percentage against this season (64.3).
  • Old Dominion ranks T12th among FBS teams for H1 opponent points per game this season (5.0).
  • Coastal Carolina ranks T134th among FBS teams for Q2 points per game this season (2.5).
  • Coastal Carolina ranks 133rd among FBS teams for points per game this season (14.5).

Coastal Carolina vs Old Dominion Prediction


Coastal Carolina has looked awful against decent competition this season and is one of the worst offenses in the country, ranked 129th in total offense and 133rd in scoring offense. Coastal Carolina also can’t stop the run, which spells trouble when going on the road. Coastal Carolina is 4-9 ATS in its last 13 games as a double-digit underdog. Old Dominion is a balanced team that’s found its groove over its last 3 games, and a top-15 rushing attack should have a field day against this Coastal Carolina defense. Thick line, but Coastal Carolina just isn’t good in key spots. I’ll lay the points with ODU at home.

Randy Chambers's Pick: Old Dominion -18.5

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