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BYU vs Iowa State Prediction 10/25/2025 Today’s College Football Picks
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BYU (7-0) vs Iowa State (5-2)
October 25, 2025 at 03:30 PM EDT
The Line: Betting Odds: Iowa State -2.5 — Over/Under: +48.5
The BYU Cougars and Iowa State Cyclones meet Saturday in college football action at Boone Pickens Stadium. Here’s a BYU vs Iowa State Prediction. This article will include a BYU vs Iowa State Pick.
BYU Cougars Betting Preview
The BYU Cougars beat Arizona and Utah, and they play Texas Tech next. BYU has won 9 straight games. Bear Bachmeier is completing 62.7 percent of his passes for 1,386 yards, 9 touchdowns, and 3 interceptions. Chase Roberts and Parker Kingston have combined for 846 receiving yards and 6 touchdowns, while Carsen Ryan has 18 receptions.
The BYU Cougars ground game is averaging 232.9 yards per contest, and LJ Martin leads the way with 774 yards and 4 touchdowns. Defensively, BYU is allowing 15.6 points and 293 yards per game. Faletau Satuala leads the BYU Cougars with 43 tackles, Jack Kelly has 5 sacks and Evan Johnson has 2 interceptions.
Iowa State Cyclones Betting Preview
The Iowa State Cyclones lost to Cincinnati and Colorado, and they play Arizona State next. Iowa State has won 6 of its last 8 games. Rocco Becht is completing 63.2 percent of his passes for 1,622 yards, 9 touchdowns, and 3 interceptions. Brett Eskildsen and Chase Sowell have combined for 595 receiving yards and 3 touchdowns, while Benjamin Brahmer has 24 receptions.
The Iowa State Cyclones ground game is averaging 190.3 yards per contest, and Abu Sama III leads the way with 481 yards and 4 touchdowns. Defensively, Iowa State is allowing 22.2 points and 402.8 yards per game. Marcus Neal Jr. leads the Iowa State Cyclones with 45 tackles, Tamatoa McDonough has 2 sacks and Jamison Patton has 2 interceptions.
Why the Iowa State Cyclones will win
- Iowa State has won each of its last three October home games against top-15 AP-ranked teams.
- The home team has covered the spread in five of Iowa State’s last six games.
Why the BYU Cougars will win
- BYU has won each of its last eight road games against non-AP-ranked teams.
- Iowa State has lost each of its last three games as a favorite against AP-ranked teams.
- Iowa State has failed to cover the spread in each of its last five games as a favorite against AP-ranked teams.
- BYU has covered the spread in each of its last three games as an underdog against non-AP-ranked teams.
Total Points Facts
- Each of Iowa State’s last four October games against AP-ranked teams have gone UNDER the total points line.
- Six of BYU’s last seven October games against non-AP-ranked teams have gone OVER the total points line.
Iowa State Cyclones Player Prop Facts
- Heading into Week 9, Benjamin Brahmer leads Iowa State for receptions (24) this season.
BYU Cougars Player Prop Facts
- Heading into Week 9, LJ Martin leads the Big 12 Conference for rushing yards (774) this season.
Matchup/League Facts
- Iowa State ranks 16th among FBS teams for H2 opponent points per game this season (7.7).
- Iowa State ranks T119th among FBS teams for red zone percentage this season (75.0).
- BYU ranks T4th among FBS teams for red zone percentage against this season (66.7).
- BYU ranks 10th among FBS teams for rushing yards per game this season (232.9).
BYU vs Iowa State Prediction
Iowa State is getting the benefit of the doubt because it’s at home, but it’s also a team that’s taking a step backwards defensively and has lost two straight winnable games. BYU keeps getting disrespected by oddsmakers but keeps finding ways to win with a balanced attack and tough play in the trenches. This BYU team is solid, and one I had beating Utah last week outright. As long as BYU stays in this form, I’ll gladly grab the points and the plus money when I can get it. BYU is tough in the trenches and can run the ball. Stop sleeping on the Cougars. Give me BYU.