Jan 21, 2024; Melbourne, Victoria, Australia; Amanda Anisimova of the United States shakes hands with Arnya Sabalenka of Belarus after losing to her in in the forth round of the women s singles at the Australian Open 2024. Mandatory Credit: Mike Frey-Imagn Images

Aryna Sabalenka vs Amanda Anisimova Prediction 9/6/2025 Today’s Tennis Picks

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US Open Final Prediction: Aryna Sabalenka vs Amanda Anisimova

September 6, 2025 at 03:00 PM EDT

The Line: Betting Odds: Aryna Sabalenka -200 / Amanda Anisimova +170

(Get latest betting odds)

Top seed and World No. 1 Aryna Sabalenka will face home favorite Amanda Anisimova in the 2025 US Open women’s final. The match is scheduled for Saturday, September 6. Here’s our Aryna Sabalenka vs Amanda Anisimova prediction. This preview will also include an Aryna Sabalenka vs Amanda Anisimova pick.

Aryna Sabalenka vs Amanda Anisimova Preview

Aryna Sabalenka reached her third straight final at the US Open, becoming the first woman since Serena Williams over a decade ago to accomplish this. The defending champion is coming off a three-set win over fourth seed Jessica Pegula in the semis. 

In a rematch of last year’s final, Sabalenka lost the first set 6-4 to the American, but did not drop her serve in the next two sets to turn the match around. Sabalenka hit 43 winners to 27 unforced errors. She accounted for eight aces and four double faults.

Sabalenka landed 67% of first serves in play and won 72% of first serve points (46/64). Sabalenka won 53% of second serve points (17/32) and saved five of seven break points in the match. Sabalenka needed to play five matches to reach the final after receiving a walkover in the quarterfinals. Sabalenka has not won a Grand Slam this year and will appear in her third final of the season in a major tournament.

Amanda Anisimova will contest her second Grand Slam final, which comes just two months after her first at Wimbledon, where she was trounced 6-0, 6-0 by Iga Swiatek. Anisimova has certainly not let that moment define or shake her confidence, and the American has enjoyed a fantastic fortnight in New York.

Anisimova got her revenge in the quarterfinals when she knocked out Swiatek in straight sets and then won a marathon semifinal against a resurgent Naomi Osaka 6-7, 7-6, 6-3 in almost three hours. Anisimova hit 50 winners and 45 unforced errors, including seven aces and six double faults. Anisimova landed 61% of first serves in play and won 67% of first serve points (49/73). She saved six of 11 break points in the match.

Aryna Sabalenka vs Amanda Anisimova Head-To-Head

Sabalenka and Anisimova have met nine times, and it is Anisimova who leads the head-to-head 6-3. They have played twice in 2025 and are locked at 1-1, with both meetings taking place in a Grand Slam.

Aryna Sabalenka vs Amanda Anisimova Prediction

This should be a cracking final, and for Anisimova, it is a shot at redemption for sure after her dismal showing at Wimbledon two months ago. She’s still a value underdog here, and the stage would probably be even bigger as she will play in front of her home fans. She can calm herself knowing she has a winning record against Sabalenka and defeated her in their last Grand Slam match.

Anisimova has also shaken off that Wimbledon loss pretty quickly and by beating the same opponent she lost to, so she will most likely handle the nerves better than in her first major final. Putting Sabalenka under duress should be the tactic here as the Belarusian is not fond of playing too many balls, and if Anisimova can come out on top in most of these diagonal exchanges, especially on the backhand wing, she’ll boss the big points. I’ll go with Anisimova to win her first Slam.

Nur Said's Pick: Amanda Anisimova in three sets

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