Nov 30, 2025; Charlotte, North Carolina, USA; Los Angeles Rams tight end Colby Parkinson (84) celebrates with Los Angeles Rams quarterback Matthew Stafford (9) during the fourth quarter against the Carolina Panthers at Bank of America Stadium. Mandatory Credit: Scott Kinser-Imagn Images
Scott Kinser-Imagn Images

Rams vs Cardinals Prediction 12/7/2025 Today’s NFL Picks

Pick details

MATCHUP Los Angeles Rams Arizona Cardinals
Team Records 9-3 3-9
Spread -8.5 -105 +8.5 -115
Moneyline -455 +350
Total Over 47.5 (-110) Under 47.5 (-110)
Where State Farm Stadium, Glendale, AZ
When Sunday, December 7, 2025
Time 04:25 PM EST
TV FOX

In this article we will formulate a Rams vs Cardinals prediction for this NFL game on Sunday, December 7th at State Farm Stadium in Glendale, Arizona. Let’s take a look at the prediction for this week 14 matchup.

Los Angeles Rams Betting Preview

The Los Angeles Rams are 9-3 this season after they lost to Carolina by a score of 31-28 in their last game. Los Angeles led 21-17 at halftime and 28-24 in the fourth quarter, but they allowed a touchdown with about six minutes left for the loss. The Rams out gained Carolina by a total of 379-358, went 2-5 on third downs, and lost the turnover battle by a total of 3-0 in the game. Matthew Stafford went 18-28 for 243 yards, two touchdowns, and two interceptions, while Blake Corum rushed seven times for 81 yards and one score. Xavier Smith led the receivers with three catches for 82 yards in the loss. 

Prior to that game, Los Angeles defeated the Buccaneers by a score of 34-7 and the Seahawks by a score of 21-19. The Rams have won six of their last seven games and they are currently tied for first in the NFC West standings. Los Angeles has scored 27.8 points per game with 246.6 passing yards and 113.5 rushing yards per game, while they have allowed 17.5 points against per game this season. Matthew Stafford has thrown for 3,073 yards, 32 touchdowns, and four interceptions, while Puka Nacua has caught 86 passes for 1,019 yards and four scores this season. 

Arizona Cardinals Betting Preview

The Arizona Cardinals are 3-9 this year after they lost to Tampa Bay by a score of 20-17 in their last game. Arizona only managed three points in the first two quarters and trailed 10-3 at halftime, but they did score 14 points in the second half in the close loss. The Cardinals out gained TB by a total of 386-279, went 3-8 on third downs, and lost the turnover battle by a total of 2-0 in the game. Jacoby Brissett went 29-40 for 301 yards, two touchdowns, and one interception, while Bam Knight rushed 11 times for 62 yards. Trey McBride led the receivers with eight receptions for 82 yards and one score in the loss. 

Prior to that game, Arizona lost to the Jaguars by a score of 27-24 and the 49ers by a score of 41-22. The Cardinals have lost four games in a row and they are currently last in the NFC West standings. Arizona has scored 22.1 points per game with 236.7 passing yards and 100.6 rushing yards per game, while they have allowed 25.3 points against per game this season. Jacoby Brissett has thrown for 2,188 yards, 13 touchdowns, and four interceptions, while Trey McBride has 88 receptions for 879 yards and eight scores this year. 

Why the Los Angeles Rams will win

  • The Cardinals have lost each of their last eight Sunday games.
  • The Rams have won each of their last 10 games as favorites following a loss.
  • The Rams have covered the spread in each of their last six Sunday games against teams that held a losing record.
  • The Cardinals have failed to cover the spread in each of their last six December games as home underdogs against NFC West opponents.
  • The Rams have won the first half in each of their last six games as favorites.
  • The Cardinals have lost the first quarter in six of their last eight December home games against NFC West opponents.

Total Points Facts

  • Each of the Cardinals’ last eight Sunday games at State Farm Stadium have gone OVER the total points line.
  • Seven of the Rams’ last eight games following a loss have gone UNDER the total points line.
  • Four of the last five games between NFC West teams have gone OVER the total points line.

Arizona Cardinals Player Prop Facts

  • Trey McBride has scored at least one touchdown in seven of the Cardinals’ last eight day games against teams that held a winning record.
  • Jacoby Brissett has recorded 25+ completions in five of the Cardinals’ last six Sunday games as underdogs.
  • Jacoby Brissett has recorded 16+ rushing yards in five of the Cardinals’ last six Sunday games as underdogs.
  • Jacoby Brissett has recorded 258+ passing yards in each of the Cardinals’ last seven games as underdogs.
  • Michael Carter has recorded 22+ receiving yards in each of his last six appearances following a loss.
  • Michael Carter has recorded 28+ rushing and receiving yards in nine of his last 10 appearances following a loss.
  • Heading into Week 14, Jacoby Brissett has recorded the most completions in a single game this season (47 vs 49ers, Week 11).

Los Angeles Rams Player Prop Facts

  • Colby Parkinson has scored a touchdown in each of the Rams’ last three games played as favorites on the West Coast.
  • Blake Corum has recorded 42+ rushing yards in four of the Rams’ last five regular season road games against NFC opponents.
  • Colby Parkinson has recorded 27+ receiving yards in three of the Rams’ last four games as favorites.
  • Matthew Stafford has recorded 272+ passing yards in seven of the Rams’ last nine games as heavy favorites (>-7.0 points).
  • Matthew Stafford has recorded 24+ completions in five of the Rams’ last six games as road favorites against NFC West opponents.
  • Puka Nacua has recorded 129+ rushing and receiving yards in three of the Rams’ last four December games as favorites against NFC opponents.
  • Heading into Week 14, Matthew Stafford is the only player in the NFL to record 20+ passing TDs and throw less than five INTs this season.

Matchup/League Facts

  • Heading into Week 14, the Cardinals have suffered the most losses by a margin of 10 points or less this season (7).
  • Heading into Week 14, the Cardinals have suffered the most losses by a margin of five points or less this season (7).
  • Heading into Week 14, the Rams have recorded the equal-most wins by a margin of 10+ points this season (6).
  • Heading into Week 14, the Rams have recorded the equal-most wins by a margin of 15+ points this season (4).

Rams vs Cardinals Prediction 

Arizona comes into this contest on a four game losing streak and they have allowed at least 27 points in three of those four losses. The Cardinals have a decent offensive attack, but their defense has been pretty rough all season. Los Angeles has been one of the best teams in the NFL this year, but they dropped an ugly game last week at Carolina. The Rams have scored at least 28 points in four of their last five and I think they are going to have a huge day offensively here. Take LA to cover on the road.

David Racey is 79-58 (58%) in the NFL this season and he is currently #2 on the NFL Leaderboard. Click here for his premium plays for this week!

David Racey's Pick: Rams -7.5

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