Los Angeles Rams vs Jacksonville Jaguars Prediction 10/19/2025 Today’s NFL Picks

The Los Angeles Rams and Jacksonville Jaguars meet Sunday in NFL action at Wembley Stadium. Here’s a Los Angeles Rams vs Jacksonville Jaguars Prediction. This article will include a Los Angeles Rams vs Jacksonville Jaguars Pick.

Los Angeles Rams Betting Preview

The Los Angeles Rams beat the Ravens, lost to the 49ers, and they play the Ravens next. The Rams have won 10 of their last 14 regular season games. Matthew Stafford is completing 66.5 percent of his passes for 1,684 yards, 12 touchdowns, and 2 interceptions. Puka Nacua and Davante Adams have combined for 1,015 receiving yards and 5 touchdowns, while Tutu Atwell has 4 receptions.

The Los Angeles Rams ground game is averaging 105.8 yards per contest, and Kyren Williams leads the way with 418 yards and 2 touchdowns. Defensively, Los Angeles is allowing 18.3 points and 306.8 yards per game. Nate Landman leads the Los Angeles Rams with 58 tackles, Byron Young has 7.5 sacks and Kam Curl has 2 interceptions.

Jacksonville Jaguars Betting Preview

The Jacksonville Jaguars beat the Chiefs, lost to the Seahawks, and they play the Raiders next. The Jacksonville Jaguars have won 5 of their last 8 games. Trevor Lawrence is completing 61.1 percent of his passes for 1,324 yards, 8 touchdowns, and 5 interceptions. Brenton Strange and Brian Thomas Jr. have combined for 538 receiving yards and 1 touchdown, while Travis Hunter has 20 receptions.

The Jacksonville Jaguars ground game is averaging 124 yards per contest, and Travis Etienne Jr. leads the way with 470 yards and 2 touchdowns. Defensively, Jacksonville is allowing 20 points and 347.8 yards per game. Foyesade Oluokun leads the Jacksonville Jaguars with 53 tackles, Arik Armstead has 3.5 sacks and Devin Lloyd has 4 interceptions.

Why the Jacksonville Jaguars will win

• The Jaguars have won three of their last four Week 7 games as underdogs.
• The Jaguars have covered the spread in four of their last five games as underdogs at neutral venues.
• The Rams have failed to cover the spread in each of their last three Week 7 games as favorites.
• The Rams have lost the first quarter in six of their last seven games as slight favorites (<-3.5 points).
• The Jaguars have won the first half in five of their last six October games at Wembley Stadium.

Why the Los Angeles Rams will win

• The Rams have won each of their last seven games against AFC opponents.
• The Jaguars have lost 14 of their last 16 games against NFC West opponents.
• The Rams have covered the spread in each of their last seven games against AFC opponents.
• The Jaguars have failed to cover the spread in seven of their last eight October games as underdogs against NFC opponents.
• The Rams have won the first quarter in 11 of their last 13 games against AFC South opponents.
• The Jaguars have lost the first half in 12 of their last 13 October games as underdogs against NFC opponents.

Total Points Facts

• Seven of the Jaguars’ last eight games following a loss have gone UNDER the total points line.
• Each of the Rams’ last five games at neutral venues have gone UNDER the total points line.

Jacksonville Jaguars Player Prop Facts

• Travis Etienne has scored a touchdown in three of the Jaguars’ last four Sunday games.
• Brian Thomas has recorded 76+ receiving yards in each of the Jaguars’ last five games as underdogs following a loss.
• Heading into Week 7, Devin Lloyd has recorded the equal-most interceptions in a single game this season (2 vs 49ers, Week 4).

Los Angeles Rams Player Prop Facts

• Kyren Williams has scored the first touchdown in each of his three previous October appearances with the Rams as favorites against AFC opponents.
• Matthew Stafford has recorded 23+ completions in five of the Rams’ last six games as favorites against AFC South opponents.
• Matthew Stafford has recorded 278+ passing yards in seven of the Rams’ last eight games as favorites against AFC South opponents.
• Kyren Williams has recorded 69+ rushing yards in 12 of his last 15 Sunday regular season appearances.
• Kyren Williams has scored at least one touchdown in seven of his eight previous October appearances.
• Kyren Williams has recorded 14+ receiving yards in each of the Rams’ last four games as favorites.
• Puka Nacua has recorded 131+ rushing and receiving yards in each of the Rams’ last four games against AFC South opponents.
• Heading into Week 7, Puka Nacua ranks 1st in the NFL in receptions (54) this season.

Matchup/League Facts

• Heading into Week 7, the Jaguars rank T1st in the NFL in turnover differential (+8) this season.
• Jaguars – six different players have recorded one interception or more in a game this season – most in the NFL, heading into Week 7.
• Heading into Week 7, the Rams rank T1st in the NFL in H2 win percentage (83.3) this season.
• Heading into Week 7, the Rams have played in the NFL’s lowest scoring game this season (17 – 3 vs Baltimore on October 12, 2025).

Los Angeles Rams vs Jacksonville Jaguars Prediction

The Jaguars have surprised up to this point, but right when you’re ready to believe in them, they have a subpar showing that reminds you of what they’ve been for the last decade. Also, even without Puka Nacua, the Rams are a talented offensive team with above-average weapons, and the Jaguars are 30th in pass defense. As I’ve said before, I’m a big fan of Sean McVay and whenever I can get the Rams at a reasonable line, I’m usually going to take it. The Rams are 11-4 ATS in their last 15 games when favorites of 3 or fewer points. The Jaguars still have some showing and proving to do. I’ll lay the small number with the Rams.