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Los Angeles Chargers vs Los Angeles Rams Prediction 8/16/2025 Today’s NFL Picks
Pick details
Los Angeles (2-0) vs Los Angeles (1-0)
August 16, 2025 at 07:00 PM EDT
The Line: Betting Odds: Los Angeles Rams +4.5 — Over/Under: +37.5
In this article, we will formulate a Chargers vs RamsPrediction for this NFL Week 2 Preseason game on Saturday, August 16th at the SoFi Stadium. Let’s take a look at the prediction for this NFL matchup.
Los Angeles Rams Preview
The Rams won the Cowboys 31-21 at home in their preseason opener last week. They outgained their opponents by 364-297 yards and had 63 total plays. They had 183 passing yards, 181 rushing yards, and 16/24 completed passes, while they had 1-1 turnovers. The Rams went 5-11 in third down efficiency and were 4-5 in the red zone. They opened the game strong, with a 14-0 score in the first period, and never looked back.
Stetson Bennett IV led the team with 16/24 passes and 188 passing yards, with 2 touchdowns and 1 interception. Cody Schrader had a team-high 59 rushing yards, while Xavier Smith caught 3 passes for 55 yards. Defensively, Nate Valcarcel had a team-high 10 total tackles, while Cam Lampkin had one interception.
The Rams went for 2-1 in the 2024 preseason, winning the opener at home by 13-12 against Dallas, followed by a 13-9 road victory against the Chargers. They lost their final game of the preseason by 15-17 in Houston.
Los Angeles Chargers Preview
The Chargers won the Saints at home with a 27-13 score in their preseason opener last week. They got outgained by their opponents by 300-248 yards and had 57 total plays. They had 9/20 completed passes, 100 passing yards, 148 rushing yards, while losing the turnover battle by 1-3. The Rams went 6-14 in third down efficiency and were 2-3 in the red zone. They opened the game strong, with a 14-0 score in the first period, and never looked back.
Trey Lance had 7/14 passes and a team-high 55 passing yards, DJ Uiagalelei went 1/1 for 49 yards and Taylor Heinicke was 1/5 for 8 yards. Trey Lance led the team in rushing yards with 48, while Dalevon Campbell caught 3 passes for 62 yards. Defensively, Emany Johnson had 11 total tackles, Caleb Murphy had 2 sacks, while Eric Rogers had 2 interceptions.
The Chargers went for 1-2 in the 2024 preseason, losing in the opener 3-16 by Seattle at home and 9-13 by the Rams at home. They won their third and final game of the preseason by 26-19 in Dallas.
Chargers vs Rams Prediction
The Chargers are 3-2 in their five meetings against the Rams, but the Rams are 3-1 against the spread in their last 4 meetings. The Rams have won both home meetings against the Chargers, and over is 3-2 in their five meetings.
In this Chargers vs RamsPrediction, the Chargers are coming as -4.5-point road favorites. Both teams are coming off victories, but the Chargers have already played two preseason games, and they looked sharp so far. They have scored an average of 30.5 points per game, and have been outscoring their opponents by 20.5 points per game. In a preseason game, I will definitely side with the team with the most games under their belt, especially when they have looked very good in both. Take the Los Angeles Chargers and lay the points on the road.
