Jacksonville Jaguars quarterback Trevor Lawrence (16) throws a pass during the Jaguars 14th NFL training camp session at Miller Electric Center Tuesday August 12, 2025 in Jacksonville, Fla. The Jaguars travel to New Orleans to play the Saints this Sunday in their second preseason game. [Doug Engle/Florida Times-Union]

Jacksonville Jaguars vs New Orleans Saints Prediction 8/17/2025 Today’s NFL Picks

Pick details

Jacksonville (0-1) vs New Orleans (0-1)

August 17, 2025 at 01:00 PM EDT

The Line: Betting Odds: New Orleans +2.5 — Over/Under: +40.5

(Get latest betting odds)

The Jacksonville Jaguars and the New Orleans Saints meet in week 2 NFL Preseason action from the Caesars Superdome on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Jacksonville Jaguars vs. New Orleans Saints prediction.

Jacksonville Jaguars Recap

The Jacksonville Jaguars come into this game looking to shake off a 31-25 loss at the hands of the Pittsburgh Steelers last time out to start the preseason 0-1. After this game, the Jaguars will finish the preseason with a game against the Miami Dolphins.

Jaguars Have Strong Showing In Opening Loss

Nick Mullens led the Jags with 89 passing yards and a touchdown on 11 of 18 passing while Seth Henigan threw for 78 yards on 11 of 14 passing. John Wolford threw for 63 yards on 3 of 5 and Trevor Lawrence went 6 of 7 for 43 yards. Bhayshul Tuten and Tank Bigsby each had 24 rushing yards with Tuten logging a touchdown while Trenton Irwin had 4 grabs for 48 yards and Jacksonville’s lone receiving TD. Dorian Singer had 40 receiving yards while Quintin Morris had 4 receptions for 39 yards. On defense, De’Antre Prince and Jabbar Muhammad each had 5 total tackles while Dawuane Smoot and Danny Striggow each had a sack.

New Orleans Saints Recap

The New Orleans Saints come into this game looking to bounce back from their 27-13 loss at the hands of the Los Angeles Chargers last time out to fall to 0-1 in the preseason. After this game, the Saints will cap off the preseason with a game against the Denver Broncos.

Saints Looking For Bounce Back

Tyler Shough threw for 165 yards, a touchdown and an interception on 15 of 22 passing while Spencer Rattler threw for 53 yards on 7 of 11 passing and rushed for a team-high 22 yards. Jake Haener also added 41 passing yards on 5 of 8 passing. Mason Tipton’s lone reception went 54 yards for a touchdown while Kevin Austin Jr. had 4 grabs for 42 yards and a TD and Cedrick Wilson JR. also chipped in 37 receiving yards and 3 catches. On defense, Isaiah Stalbird added a team-high 8 total tackles with 6 solo tackles and Jaylan Ford also had 8 total tackles. Fadil Diggs, Chris Rumph II and Khristian Boyd all had sacks as well in the losing effort for New Orleans.

Jacksonville Jaguars vs. New Orleans Saints Prediction

I’m leaning towards the Jaguars here. I’m just not all that impressed with the talent in the Saints’ quarterback room, as Spencer Rattler, Jake Haener and Tyler Shough aren’t needle movers for me. The Jaguars have plenty of experience, especially at QB, with guys that have seen starting time at the NFL level in their careers like Wolford and Nick Mullens, and I think they have the better depth pieces across the board, not just at QB. Give me the Jags here.

Chris Ruffolo's Pick: Jacksonville -2.5

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