Green Bay Packers vs Arizona Cardinals Prediction 10/19/2025 Today’s NFL Picks

In this article, we will formulate a Packers vs Cardinals Prediction for this NFL Week 7 game on Sunday, October 19th at the State Farm Stadium. Let’s take a look at the prediction for this NFL matchup.

Arizona Cardinals Preview

The Arizona Cardinals have a 2-4-0 record this season and are sitting fourth in the NFC West. They are 3-3 ATS, 3-3 in Over/Under and have a 1-2 home record and a 1-2 away record. The Cardinals are coming off a 27-31 road loss against the Indianapolis Colts and will face the Packers, Cowboys and the Seahawks next.

Offensively, the Cardinals average 21.7 points per game, ranking 20th in the NFL, while defensively, they allow 21.2 points per game, which is 14th. Arizona averages 307.0 total yards per game (193.8 passing and 113.2 rushing), while allowing 348 total yards per game (102 rushing and 246 passing).

Kyler Murray leads the Cardinals with 962 passing yards with 68.3% completed passes and 6 touchdowns. Kyler Murray leads the team in rushing yards with 173, while Trey McBride has a team-high 37 receptions for 347 receiving yards, and two touchdowns. Defensively, Mack Wilson has a team-high 50 total tackles (28 of them solo), while Josh Sweat leads the team in sacks, with 5.0, while Dadrion Taylor-Demerson has two interceptions.

Green Bay Packers Preview

The Green Bay Packers have a 3-1-1 record this season and are sitting first in the NFC North. They are 2-3 ATS, 1-3-1 in Over/Under and have a 3-0 home record and a 0-1-1 away record. The Packers are coming off a 27-18 home win against the Cincinnati Bengals and will face the Cardinals, Steelers and the Panthers next.

Offensively, the Packers average 26.2 points per game, ranking 8th in the NFL, while defensively, they allow 20.4 points per game, which is 10th. Green Bay averages 359.6 total yards per game (237.4 passing and 122.2 rushing), while allowing 280.2 total yards per game (73.0 rushing and 207.2 passing).

Jordan Love leads the Packers with 1259 passing yards with 70.1% completed passes and 9 touchdowns. Josh Jacobs leads the team in rushing yards with 359, while Tucker Kraft has a team-high 18 receptions for 268 receiving yards, and three touchdowns. Defensively, Quay Walker has a team-high 50 total tackles (27 of them solo), while Rashan Gary leads the team in sacks, with 4.5, while Xavier McKinney and Evan Williams each have one interception.

Green Bay Packers @ Arizona Cardinals Betting Trends: Week 7

Why the Arizona Cardinals will win

• The home team has won each of the Cardinals’ last five Week 7 games.
• The Packers have lost three of their last four games as road favorites following a home win.
• The Packers have failed to cover the spread in each of their last six Sunday games against teams that held a losing record.
• The Cardinals have covered the spread in each of their last six October games as home underdogs against NFC opponents.
• The Cardinals have scored the first touchdown in each of their last eight Sunday home games.
• The Packers have won the first quarter in each of their last eight games as moderate favorites (-3.5 to -7.0 points).
• The Cardinals have won the first half in each of their last four Sunday home games.

Why the Green Bay Packers will win

• The Packers have won 10 of their last 11 October games against NFC West opponents.
• The Cardinals have lost each of their last four games.
• The Packers have covered the spread in each of their last seven games against NFC West opponents.
• The Cardinals have failed to cover the spread in each of their last four October games against NFC North opponents.
• The Packers have won the first quarter in 10 of their last 11 October games against NFC West opponents.
• The favorites have won the first half in each of the Cardinals’ last eight games.
• The Packers have scored the first touchdown in each of their last 12 games as favorites against NFC West opponents.

Total Points Facts

• Each of the Cardinals’ last eight games played as underdogs on the West Coast have gone UNDER the total points line.
• Eight of the Packers’ last nine road games following a home win have gone OVER the total points line.
• Each of the last five Sunday games at State Farm Stadium have gone OVER the total points line.

Arizona Cardinals Player Prop Facts

• Elijah Higgins has recorded 11+ receiving yards in each of the Cardinals’ last five Sunday games as home underdogs.
• Jacoby Brissett has recorded 234+ passing yards in each of his last three October appearances against NFC opponents.
• Michael Carter has recorded 34+ rushing yards in five of his last six appearances following a loss.
• Trey McBride has scored a touchdown in each of the Cardinals’ last three day games against teams that held a winning record.
• Michael Carter has recorded 48+ rushing and receiving yards in each of his last four Sunday appearances.
• Jacoby Brissett has recorded 22+ completions in three of his four previous Week 7 appearances.
• Trey McBride has recorded the equal-most targets (53) of any player yet to record a drop this season.

Green Bay Packers Player Prop Facts

• Jordan Love has recorded 258+ passing yards in four of the Packers’ last five games as moderate favorites (-3.5 to -7.0 points).
• Tucker Kraft has scored at least one touchdown in four of the Packers’ last five October games.
• Romeo Doubs has recorded 49+ receiving yards in each of the Packers’ last four October games.
• Jordan Love has recorded 12+ rushing yards in each of the Packers’ last four games.
• Jordan Love has recorded 20+ completions in three of the Packers’ last four road games against NFC opponents.
• Heading into Week 7, Romeo Doubs has recorded the equal-most receiving touchdowns in a single game this season (3 vs Cowboys, Week 4).

Matchup/League Facts

• Cardinals – 10 different players have recorded at least one touchdown this season – equal-most in the NFL, heading into Week 7.
• Heading into Week 7, the Cardinals rank 1st in the NFL in Q3 opponent points per game (2.0) this season.
• Heading into Week 7, the Packers rank 1st in the NFL in rushing yards allowed per game (73.0) this season.
• Heading into Week 7, the Packers rank 1st in the NFL in 3rd down percentage (52.3%) this season.

Packers vs Cardinals Prediction

In their previous meeting last season, the Packers won 34-13 at home, but the Cardinals are 3-2 in their last 5 meetings, and are 3-1 in their last 4 meetings in Arizona. Under is 4-0-1 in their last 5 meetings.  

In this Packers vs Cardinals Prediction, the Packers are coming as -6.5-point road favorites, with the total set at 44.5 points. The Cardinals are on a free fall lately, as they have four consecutive losses after winning their first two games of the season. On the flip side, the Packers have lost only once in their last five games, and are better both offensively and defensively than the Cardinals, winning by an average of 5.8 points per game. I like Green Bay as a road favorite in this spot, so take the Packers and lay the -6.5 points in this one.