Falcons vs Panthers Prediction 9/21/2025 Today’s NFL Picks

In this article we will formulate a Falcons vs Panthers prediction for this NFL game on Sunday, September 21st at Bank of America Stadium in Charlotte, North Carolina. Let’s take a look at the prediction for this week 3 matchup.

Atlanta Falcons Betting Preview

The Atlanta Falcons are 1-1 this year after they defeated Minnesota by a score of 22-6 last week. Atlanta led 6-0 after the first quarter and 9-6 at halftime, before pitching a shutout in the second half for the nice victory. The Falcons out gained Minnesota by a total of 326-198, went 6-15 on third downs, and lost the turnover battle by a margin of 4-1 in the game. Michael Penix Jr. went 13-21 for 135 yards, while Bijan Robinson carried the ball 22 times for 143 yards. Drake London led the receivers with three catches for 49 yards in the game. The Atlanta defense recorded six sacks and five tackles for loss in the win. 

Atlanta started the season with a 23-20 loss to Tampa Bay in week one, as they missed a game tying field goal to end the game. The Falcons are averaging 21.0 points per game with 198.5 passing yards and 143.5 rushing yards per game, while they are allowing 14.5 points against per game this season. Michael Penix Jr has completed 63.5% of his passes for 433 yards and one touchdown, while Bijan Robinson has caught nine passes for 125 yards and one score. Robinson is also the leading rusher, as he has 34 carries for 167 yards this season. 

Carolina Panthers Betting Preview

The Carolina Panthers are 0-2 this season after they lost to Arizona by a score of 27-22 in their last game. Carolina trailed 10-3 after the first quarter and 27-3 in the third, but they scored the last 19 points and nearly tied the game. The Panthers out gained Arizona by a total of 352-293, went 5-15 on third downs, and lost the turnover battle by a total of 2-1 in the game. Bryce Young went 35-55 for 328 yards, three touchdowns, and one interception, while Chuba Hubbard rushed 10 times for 38 yards. Tetairoa McMillan led the receivers with six catches for 100 yards in the loss. The Carolina defense recorded one sack and four tackles for loss in the game. 

Carolina opened the 2025 season with a 26-10 loss against Jacksonville, so defense is definitely a concern for them. The Panthers are averaging 16.0 points per game with 222.5 passing yards and 81.0 rushing yards per game, while they are allowing 16.0 points against per game this season. Bryce Young has completed 58.9% of his passes for 482 yards, four touchdowns, and three interceptions, while Tetairoa McMillan has caught 11 passes for 168 yards. Chuba Hubbard is the leading rusher for Carolina with 26 carries for 95 yards this year. 

Why the Panthers will beat the Falcons 

The underdogs have won five of the last six games between the Falcons and Panthers at Bank of America Stadium.
The Falcons have lost three of their last four Sunday games as favorites.
The Falcons have failed to cover the spread in 10 of their last 11 road games following a road win.
The Panthers have covered the spread in seven of their last eight games as underdogs against NFC opponents.
The Falcons have lost the first quarter in four of their last six games as road favorites following a win.
The Falcons have lost the first half in four of their last five road games in September.

Total Points Facts

Each of the Panthers’ last seven Sunday games at Bank of America Stadium have gone OVER the total points line.
Six of the Falcons’ last seven games in September have gone UNDER the total points line.
Eight of the last 10 Sunday games at Bank of America Stadium have gone OVER the total points line.

Carolina Panthers Player Prop Facts

Chuba Hubbard has scored at least one touchdown in seven of his last eight Sunday appearances with the Panthers as underdogs.
Chuba Hubbard has recorded 72+ rushing yards in four of the Panthers’ last five games as home underdogs against NFC South opponents.
Bryce Young has recorded 219+ passing yards in four of the Panthers’ last five games following a road loss.
David Moore has recorded 17+ receiving yards in each of the Panthers’ last six Sunday games at Bank of America Stadium.
Rico Dowdle has recorded 51+ rushing and receiving yards in each of his last seven regular season home appearances against NFC opponents.
Andy Dalton has recorded 25+ completions in three of his four previous appearances at Bank of America Stadium.
Heading into Week 3, Tommy Tremble ranks T1st amongst qualified players for catch rate (100.0%) this season.

Atlanta Falcons Player Prop Facts

Bijan Robinson has scored two touchdowns in each of the Falcons’ last three games as favorites against NFC opponents.
Bijan Robinson has recorded 86+ rushing yards in each of the Falcons’ last six games following a win.
Bijan Robinson has scored at least one touchdown in eight of the Falcons’ last nine Sunday games played on the East Coast.
Kirk Cousins has recorded 296+ passing yards in each of his three previous Week 3 road appearances.
Ray-Ray McCloud has recorded 30+ receiving yards in six of the Falcons’ last seven games against NFC South opponents.
Ray-Ray McCloud has recorded 33+ rushing and receiving yards in six of the Falcons’ last seven games against NFC South opponents.
Kirk Cousins has recorded 23+ completions in four of his last five Sunday appearances with the Falcons as favorites.
Heading into Week 3, Mike Ford ranks T1st in the league for fumbles recovered (1) this season.

Matchup/League Facts

Heading into Week 3, the Panthers rank 32nd in the NFL in Q2 opponent points per game (13.5) this season.
Heading into Week 3, the Panthers rank 32nd in the NFL in H1 points per game (3.0) this season.
Falcons – two different players have recorded 70+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
Falcons – one different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.

David Racey is 6-3 (67%) in his last nine NFL plays this season. Click here for his premium plays for this week!

Falcons vs Panthers Prediction 

Carolina comes into this contest looking for their first win of the season, but they will be back at home for this one. The Panthers have not played well defensively in either game, but they did show some heart last week and nearly came away with a huge comeback win. Atlanta played very sloppy against Minnesota in their last game and they were fortunate that the Vikings couldn’t move the ball. I do think Atlanta is the better team, but Penix did have some issues last week and I think Carolina has some much needed momentum after that fourth quarter. Give me the points with the Panthers at home.